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  • 1
    ISSN: 1432-1076
    Keywords: Bare lymphocyte syndrome ; HLA expression ; Severe combined immunodeficiency syndrome ; Neutrophil dysfunction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 4-year-old girl presented with recurrent infections. Immunoglobulin deficiency (serum and secretory IgA, serum IgG3) neutropenia and neutrophil dysfunction (defective spontaneous migration and chemotaxis) were found. T-lymphocyte counts were normal and they responded to phytohaemagglutinin but were not stimulated by Concanavalin A, pokeweed mitogen and microbial antigens in vitro. Delayed cutaneous hypersensitivity testing to purified protein derivative and candidin was negative. Despite bacille Calmette-Guérm vaccination and candidiasis, near normal β-2-microglobulin and human leucocyte antigen (HLA) class I concentrations were detected on mononuclear cells and phytohaemagglutinin-induced lymphoblasts. HLA class II antigens (HLA-DP, −DQ, −DR) were not expressed. These observations indicated a bare lymphocyte syndrome (BLS) type II. This is the first time neutrophil dysfunction has been noted in association with BLS.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1365-3091
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Lower Pliocene temperate carbonates exhibit landward-downlapping beds at the southern margin of the Carboneras Basin in south-eastern Spain. This rarely documented stratal geometry resulted from the accumulation of bedded bioclastic carbonate sand and gravel by longshore currents along a spit platform located a few hundred metres from the palaeoshoreline. The top of the spit platform was covered by shoals that extended over a gently dipping ramp inclined to the north. On the landward slope of the spit, sediments washed over from the shoal area were deposited in parallel-laminated beds with a southward dip of 8–11°. These beds aggraded and retrograded after an increase in accommodation space, probably related to an Early Pliocene eustatic sea-level rise. As a result, the beds downlap onto the underlying unconformity surface in a shoreward direction. Eventually, the depression between the shoreline and the spit platform was filled, and a gentle ramp became established. These Pliocene exposures in the Carboneras Basin and a similar Upper Miocene example in southern Spain suggest that landward-downlapping stratal geometries can be expected in nearshore temperate carbonates along basin margins, and demonstrate a similarity in sedimentary dynamics to siliciclastic sands and gravels.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International journal of earth sciences 89 (2000), S. 140-153 
    ISSN: 1437-3262
    Keywords: Carbonate ramp ; Turbidites ; Sequence stratigraphy ; Cycles ; Sea level ; Bahamas ; Miocene
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0016-7835
    Keywords: Key words Miocene ; Palaeoceanography ; Climatic changes ; Sea-level fluctuations ; Chlorozoan reefs ; Bryomol ramps
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  In order to evaluate the geological record of climatic change in neritic carbonates, we studied Late Miocene rock outcrops in southern Spain. Six episodes of reef growth are documented (Burdigalian to Messinian) in Neogene basins of the Betic Cordillera, which were located close to the margin of the global reef belt. The reefs are characterized by various zooxanthellate corals which decrease in diversity with time, and Halimeda; the youngest reefs of the latest Messinian are characterized by the dominance of the genus Porites. Late Miocene coral reefs and reef-rimmed platforms alternate over time with non-reefal carbonate ramps characterized by skeletal calcirudites or with gypsum such as that formed during the Messinian salinity crisis. The calcirudites lack reef corals, calcified green algae and extensive marine cement, but exhibit skeletal components described from both modern and fossil non-tropical carbonates. These include bryozoans, mollusks, foraminifers, echinoderms and minor balanids, as well as coralline algae of a bryomol association. The presence of some larger foraminifers indicates high temperatures, close to the lower temperature threshold of the reef assemblage. Sea level lowstands and highstands are documented by wedges of bryomol carbonate and chlorozoan patch reefs or prograding platforms. Thus, temperate climate depositional modes correspond to relatively low sea levels, and warm-water modes to high sea levels. The Neogene infill of the Agua Amarga and Sorbas basins documents two of these cycles. Other climate/sea-level cycles (including Messinian gypsum in the cool water depositional mode) are well established in adjacent Neogene basins in southern Spain. This type of composite sequence seems to occur only along the margin of the global reef belt and indicates an oscillatory latitudinal movement of the margin, which is associated with global climatic change. The analysis of turnover in neritic depositional carbonate systems may therefore be considered a sensitive tool for reconstructing climatic change from the fossil record. However, warm-water modes and temperate-water modes of carbonate sedimentation and diagenesis differ significantly. For this reason the interpretation of composite system sequences by sequence stratigraphy requires an extended concept. The particular type of mixed bryomol–chlorozoan depositional sequence also bears some potential for drowning, because sea level rise may be faster than the net production rate of temperate carbonate systems.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1437-3262
    Keywords: Miocene ; Palaeoceanography ; Climatic changes ; Sea-level fluctuations ; Chlorozoan reefs ; Bryomol ramps
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract In order to evaluate the geological record of climatic change in neritic carbonates, we studied Late Miocene rock outcrops in southern Spain. Six episodes of reef growth are documented (Burdigalian to Messinian) in Neogene basins of the Betic Cordillera, which were located close to the margin of the global reef belt. The reefs are characterized by various zooxanthellate corals which decrease in diversity with time, andHalimeda; the youngest reefs of the latest Messinian are characterized by the dominance of the genusPorites. Late Miocene coral reefs and reef-rimmed platforms alternate over time with non-reefal carbonate ramps characterized by skeletal calcirudites or with gypsum such as that formed during the Messinian salinity crisis. The calcirudites lack reef corals, calcified green algae and extensive marine cement, but exhibit skeletal components described from both modern and fossil nontropical carbonates. These include bryozoans, mollusks, foraminifers, echinoderms and minor balanids, as well as coralline algae of a bryomol association. The presence of some larger foraminifers indicates high temperatures, close to the lower temperature threshold of the reef assemblage. Sea level lowstands and highstands are documented by wedges of bryomol carbonate and chlorozoan patch reefs or prograding platforms. Thus, temperate climate depositional modes correspond to relatively low sea levels, and warm-water modes to high sea levels. The Neogene infill of the Agua Amarga and Sorbas basins documents two of these cycles. Other climate/sea-level cycles (including Messinian gypsum in the cool water depositional mode) are well established in adjacent Neogene basins in southern Spain. This type of composite sequence seems to occur only along the margin of the global reef belt and indicates an oscillatory latitudinal movement of the margin, which is associated with global climatic change. The analysis of turnover in neritic depositional carbonate systems may therefore be considered a sensitive tool for reconstructing climatic change from the fossil record. However, warm-water modes and temperate-water modes of carbonate sedimentation and diagenesis differ significantly. For this reason the interpretation of composite system sequences by sequence stratigraphy requires an extended concept. The particular type of mixed bryomolchlorozoan depositional sequence also bears some potential for drowning, because sea level rise may be faster than the net production rate of temperate carbonate systems.
    Type of Medium: Electronic Resource
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