Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 11
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical microbiology & infectious diseases 9 (1990), S. 697-699 
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The in vitro activity of cilofungin (LY121019), a new semi-synthetic antifungal agent was evaluated. Potent activity was seen againstCandida albicans andCandida tropicalis, with almost identical MIC and MFC results, whereas no activity was seen against any isolates ofCandida parapsilosis or threeAspergillus spp. However, MICs were dependent on medium and test conditions chosen. It is concluded that cilofungin has good activity against some medically important yeasts in vitro, and that its in vitro activity depends on the method used.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 12
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical microbiology & infectious diseases 9 (1990), S. 832-835 
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a model of bronchopulmonary aspergillosis terbinafine did not improve survival of experimental animals in doses up to 80 mg/kg/day despite adequate lung concentrations. Pretreatment and aerosolization of the compound were also ineffective. Terbinafine was markedly less active in vitro when serum was used instead of Yeast-Nitrogen-Glucose-broth. It is concluded that a lack of bioavailability in the presence of serum may explain the lack of activity of terbinafine in experimental aspergillosis.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 13
    ISSN: 1432-1440
    Keywords: Calcium carbonate ; Phosphate ; Chronic renal failure ; Aluminium ; Hyperparathyroidism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Calcium carbonate has been successfully used as a phosphate binder in patients with chronic renal failure; however, a high frequency of hypercalcaemia has been reported. To study the effects of calcium carbonate preparations with different dissolution characteristics on the incidence of this side effect, we conducted a double-blind, crossover trial in 21 patients undergoing chronic haemodialysis. Aluminium hydroxide therapy was replaced with calcium carbonate. The subjects then randomly received either an enteric-coated or a gastric-coated preparation. Calcium carbonate (3.1–3.6 g/d) controlled serum phosphate concentrations as effectively as aluminium hydroxide (2.9 g/d). Concurrently, there was a significant rise in mean serum calcium and a fall in serum concentrations of both parathyroid hormone and osteocalcin, the latter suggesting a decrease in bone turnover. Overall, hypercalcaemic episodes developed in 9 patients (43%) and occurred at a considerable frequency (33 episodes per 100 patient-months) during treatment with the gastric-coated formulation. Following conversion to enteric-coated calcium carbonate (3.6 g/d) patients had fewer occurrences of hypercalcaemia (12 episodes per 100 patient-months,P〈0.05) and, as compared to the gastric-coated preparation, increases in serum calcium 〉3.00 mmol/l were not observed at all. Hyperaluminaemia was regressive during therapy with calcium carbonate, but addition of small doses of aluminium hydroxide caused a large rise in serum aluminium concentrations after infusion of desferrioxamine, indicating an enhanced rate of absorption or aberrant compartmentalization of aluminium. We conclude that calcium carbonate can control hyperphosphataemia in dialysis patients. However, undesirable hypercalcaemic episodes may occur, the frequency and severity of which can be lowered by the use of an enteric-coated preparation. Concomitant use of aluminium hydroxide and calcium carbonate should be restricted to patients in whom the degree of aluminium accumulation is monitored by serial desferrioxamine tests.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 14
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 86 (1992), S. 207-215 
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The nature of the optical absorption gap in NiO at 4.0 eV is investigated. It is found that this gap is due to a band to band transition, where an electron is taken out of the valence band and placed into the conduction band. The optical gap of 6.0 eV found in Ni∶MgO is of a nature, where an electron is taken out of the oxygen 2p band and placed into the first affinity level of the Ni2+ ion (3d 8L»3d 9L−1). The impurity band created in Ni1−x Li x O by the Li ions is found 2.3 eV below the bottom of the conduction band in agreement with model predictions.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 15
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 88 (1992), S. 247-248 
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The electronic structure of the Li doped large gap semiconductor (insulator) NiO is investigated by photoemission and inverse photoemission spectroscopy. Spectral weight is produced by the Li doping within the gap at 1.4 eV above the top of the valence band. It is interpreted as due to an acceptor level associated with a LiO complex.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 16
    Electronic Resource
    Electronic Resource
    Springer
    Infection 18 (1990), S. 100-100 
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 17
    Electronic Resource
    Electronic Resource
    Springer
    Infection 21 (1993), S. 89-92 
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Inzidenz von ZNS-Shuntinfektionen und damit verbundenen Risikofaktoren wurde durch Auswertung von Krankenakten untersucht. Zwischen 1986 und 1989 wurden 350 Shunt-Operationen durchgeführt, wobei 273 Shunts ventrikuloperitoneal und 75 ventrikuloatrial plaziert wurden. Bei 25 Patienten kam es während eines mittleren Beobachtungszeitraumes von 20 Monaten zu 28 Shuntinfektionen (8 %). Für 204 Patienten konnte die Nachbeobachtungszeit bis September 1992 ausgedehnt werden, weitere Infektionsfälle wurden in dieser Gruppe nicht beobachtet. In 24 Fällen (85,7 %) konnte ein ursächlicher Erreger isoliert werden. Bei den Erregern handelte es sich um grampositive Kokken in 22 Fällen (78,6 %) und um gramnegative Stäbchen in zwei Fällen. Hauptsymptome und -Befunde waren Fieber, Shuntdysfunktion und meningeale Reizerscheinungen sowie Bauchschmerzen (letztere ausschließlich bei VP-Shunts). Bei 24 Infektionsfällen wurde der Shunt sofort entfernt und eine antibiotische Therapie begonnen, in den übrigen Fällen erfolgte ausschließlich eine antibiotische Therapie. Ursache des Hydrozephalus, Shuntlage, perioperative Antibiotikagabe, Alter und Geschlecht eines Patienten waren nicht mit einem erhöhten Infektionsrisiko assiziiert, jedoch ergab sich ein Trend, der ein erhöhtes Infektionsrisiko mit der Operationsdauer zeigte. Die Infektionsrate lag bei 13,6% für eine Operationsdauer von 〉90 Minuten, während sie bei 5,2 % für Eingriffe mit einer Dauer von 〈30 Minuten lag.
    Notes: Summary The incidence of shunt infections and possible risk factors was investigated by chart analysis. From 1986 to 1989 350 shunt procedures were performed including 273 ventriculoperitoneal shunts and 75 ventriculoatrial shunts. Twenty-eight infectious episodes (8%) occurred in 25 patients during a median follow-up time of 20 months. For 204 patients the follow-up time could be prolonged until September 1992. In these patients no infectious episodes occurred in the extended observation period. In 24 cases (85.7%) a causative organism could be isolated. The infecting organisms were gram-positive cocci in 22 cases (78.6%) and gram-negative bacilli in two cases. The main signs and symptoms were fever, shunt malfunction and meningeal irritation, and with VP-shunts only, abdominal pain. Twenty-four infectious episodes were treated with antibiotics and immediate removal of the shunt. The remaining were managed with antibiotics only. The risk for shunt infection did not correlate with age or sex of patients, nor with the etiology of hydrocephalus, type of shunt implanted or perioperative antibiotic prophylaxis. However, a trend showing a higher risk for shunt infections with prolonged operation time was noticed. The infection rate was 13.6% for an operation lasting more than 90 minutes versus 5.2% for procedures of less than 30 minutes' duration.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 18
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We present results of the total cross section differenceΔσ Т obtained in transmission measurements at the energies 0.86, 0.88, 0.91 and 0.94 GeV. The SATURNE II polarized beam of free neutrons obtained from the break-up of polarized deuterons was transmitted through the polarized Saclay frozen-spin proton target. The beam and target polarizations were oriented in the vertical direction. The present results agree with previous SATURNE measurements and improve the amplitude analysis in the forward direction.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...