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  • 1
    Electronic Resource
    Electronic Resource
    On-Line Particle Size Analyzer (1967)
    s.l. : American Chemical Society
    Industrial and engineering chemistry 6 (1967), S. 587-592 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/i160024a015
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  • 2
    Electronic Resource
    Electronic Resource
    The high prognostic value of the histologic grade at the deep invasive front of tongue squamous cell carcinoma (2005)
    Oxford, UK : Munksgaard International Publishers
    Journal of oral pathology & medicine 34 (2005), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background:  Although many histopathologic factors in squamous cell carcinoma of the tongue predict the prognosis, the major predictive factors have not been identified clearly. This study analyzed the prognostic value of the histologic grade at the deep invasive front of tongue squamous cell carcinoma.Methods:  The clinicopathologic features of 124 consecutive patients seen between January 1985 and December 1999 with previously untreated squamous cell carcinoma of the tongue were reviewed. Their mean age was 58.5 years (range: 23–90) and the male–female ratio was 1.8: 1 (79 men and 45 women). There were 41, 40, 30, and 13 cases at stage I to stage IV, respectively. The clinicopathologic factors, especially the histologic grade at the deep invasive front (invasive front grade, IFG), were analyzed to determine factors predicting prognosis.Results:  The 5-year disease-free survival rate of the patients treated with curative aim only was 66.7%. Clinicopathologic factors significantly associated with the prognosis were T classification, tumor size, stage classification, tumor depth, macroscopic appearance, cervical lymph node metastasis (nodal metastasis), microvascular invasion, and IFG. In a multivariate analysis, patients with tumor depth ≥4 mm, IFG ≥8 points, and nodal metastasis had a reduced disease-free survival and IFG ≥11 points had a predictive value for nodal metastasis (odds ratio: 7.34; P = 0.0019).Conclusion:  This study found that a high IFG malignancy score had a high prognostic value for squamous cell carcinoma of the tongue.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.2005.00244.x
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  • 3
    Electronic Resource
    Electronic Resource
    Cleavage of nucleolin and AgNOR proteins during apoptosis induced by anticancer drugs in human salivary gland cells (2005)
    Oxford, UK : Munksgaard International Publishers
    Journal of oral pathology & medicine 34 (2005), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background:  To investigate the behavior of nuclear proteins in apoptosis induced by anticancer drugs in cultured human salivary gland (HSG) cells.Methods:  Dynamic alternations of nucleolin and argyrophilic nucleolar organizer region (AgNOR) proteins in anticancer drug-induced apoptosis of HSG cells and in a cell-free apoptotic system were examined using Western blot analysis and immunocytochemical method.Results:  The 110-kDa form of nucleolin and AgNOR protein decreased and the 80- and 95-kDa forms appeared during apoptosis in HSG cells and in a cell-free apoptotic system. In addition, the induction of DNA ladder formation coincided with the appearance of alternation of nucleolin and AgNOR proteins in a cell-free apoptosis. Nucleolin diffusely spread out into the nuclear material in the apoptotic body of HSG cells.Conclusions:  The present results indicate that alternations of nucleolin and AgNOR proteins are associated with the induction of DNA fragmentation and the final active phase of apoptosis induced by anticancer drugs in malignant salivary gland cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.2005.00346.x
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  • 4
    Electronic Resource
    Electronic Resource
    In vitro evaluation of the bonding of auto-polymerizing soft denture liner to cobalt–chromium alloy (2005)
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 32 (2005), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary  This study evaluated the effects of surface pre-treatments on the bonding of auto-polymerizing silicone soft denture liner to a Co–Cr alloy denture base after cyclic thermal stressing. The bonding surfaces of Co–Cr alloy cylinders (8 mm diameter and 4 mm high) were polished with a 600-grit silicon carbide paper. The bonding surfaces received one of three pre-treatments, which included either the application of a metal primer, a metal primer after air abrasion, or a resin primer after adhesive resin coating. Tensile specimens were fabricated by polymerizing a 2-mm thickness of soft denture liner between a pair of pre-treated denture base cylinders. Failure loads were measured by tensile testing after subjecting the specimen to 0, 5, 10, 20, and 30 thousand thermal cycles. Seven specimens were fabricated for 15 groups, including three pre-treatments and five thermal cycle groups. Failure loads of resin-bonded specimens, which were formerly reported, were used as references. All data were statistically analysed by two-way anova and Bonferroni test at the 95% confidence level. Adhesive resin coating of the metal surface was effective in enhancing the failure loads up to 5000 thermal cycles. However, failure loads of all metal-bonded groups were significantly lower than those of resin-bonded groups at all thermal cycling intervals. The results of this in vitro study implied that polymerizing adhesive resin on the Co–Cr alloy might be a promising method, when the clinicians need to acquire improved bonding of an auto-polymerizing soft denture liner to Co–Cr alloy denture bases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2842.2005.01428.x
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  • 5
    Electronic Resource
    Electronic Resource
    Prevalence of atopic dermatitis in Japanese elementary schoolchildren (2005)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 152 (2005), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Although there have been several reports on the prevalence of atopic dermatitis (AD) in Japanese schoolchildren based on questionnaires, there has been no nation-wide study of the frequency of this condition diagnosed by dermatologists in regular health check-ups of schoolchildren.Objectives  The objective of this work was to evaluate precisely the prevalence of AD in elementary schoolchildren in Japan based on regular health check-ups by dermatologists.Methods  In 2001/2, elementary schoolchildren: first graders (age 6–7 years) and sixth graders (age 11–12 years) were examined by dermatologists in eight prefectures of Japan (Hokkaido, Iwate, Tokyo, Gifu, Osaka, Hiroshima, Kochi and Fukuoka). In each prefecture, public elementary schools were randomly selected from urban and rural districts. We planned to examine about 700 schoolchildren in each of urban first, urban sixth, rural first and rural sixth grades from the eight areas, a total of 22 400 children (700 × 4 × 8). AD was diagnosed by the dermatologists based on the Japanese Dermatological Association criteria for the disease.Results  The point prevalence of AD was 11·2% overall (2664 of 23 719) ranging from 7·4% (Iwate) to 15·0% (Fukuoka) in the eight areas. Seventy-four per cent, 24%, 1·6% and 0·3% of those afflicted were in the mild, moderate, severe and very severe groups, respectively. Overall, the prevalence of first graders was slightly higher than that of sixth graders (11·8% vs. 10·5%, P 〈 0·01). There was no apparent difference in prevalence between urban and rural districts, or between boys and girls.Conclusions  The prevalence of AD in Japanese elementary schoolchildren was about 10%, three-quarters of those being mildly affected. This is the first nation-wide study made of Japanese elementary schoolchildren examined by dermatologists to evaluate the frequency of AD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.2004.06271.x
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  • 6
    Electronic Resource
    Electronic Resource
    Subcellular distribution and binding of heavy metals in the untreated liver of the squid; comparison with data from the livers of cadmium and silver-exposed rats (1983)
    Springer
    Cellular and molecular life sciences 39 (1983), S. 746-748 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In natural squid liver, about 30% of the total Cd present was found in the cytosolic fraction. A large portion of this Cd was bound to high molecular weight species (mol. wt〉70,000). In contrast to Cd, about 60% of the total Ag occurred in the cytosolic fraction; Ag was bound mainly to low molecular weight species (mol. wt〈20,000).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01990305
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  • 7
    Electronic Resource
    Electronic Resource
    Pleomorphic intra-neuronal polyglucosan bodies mainly restricted to the pallidium (1983)
    Springer
    Acta neuropathologica 62 (1983), S. 159-163 
    Details
    ISSN: 1432-0533
    Keywords: Pleomorphic polyglucosan body ; Bielschowsky body ; Lafora body ; Corpora amylacea
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A rare case with pleomorphic intra-neuronal polyglucosan bodies is reported. A 45-year-old man died of gastric carcinoma with extensive visceral involvement. The autopsy showed numerous intra-neural pleomorphic PAs-positive deposits reminiscent of Bielschowsky bodies in the lateral segments of the pallidum, substantia nigra, and brain stem on both sides. Their histochemical properties were consistent with polyglucosan. The bodies were ultrastructurally composed of filamentous structures and seen in perikarya, axons, and dendrites. Occasionally, spotty electron-dense material was seen in the center of the bodies. The filaments were selectively stained with thiocarbohydrazide method after Thiéry, indicating their chief component as glucose polymers. The bodies are compared with Bielschowsky bodies, Lafora bodies, corpora amylacea, and related bodies, and their nature and significance are briefly discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00684936
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  • 8
    Electronic Resource
    Electronic Resource
    Cytochemical changes in lactate dehydrogenase isoenzymes in human brain tumours (1984)
    Springer
    Acta neurochirurgica 71 (1984), S. 243-253 
    Details
    ISSN: 0942-0940
    Keywords: Brain tumours ; LDH isoenzyme ; cytochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The lactate dehydrogenase (LDH) isoenzyme patterns in benign and malignant brain tumours were determined by means of electrophoresis of the cell extracts and selective cytochemical stain of the smears. The LDH isoenzyme distribution of the cell extracts showed a pronounced cathodal shift in the malignant gliomas and metastatic carcinomas. Normal brain tissues and histologically benign gliomas, however, showed an anodal pattern with a dominance of the H-type LDH. Schwannomas and meningiomas had a midzone isoenzyme pattern with a dominant LDH3 fraction. Pituitary adenomas usually showed the LDH pattern similar to that of the normal cerebrum. The LDH M fraction could be cytochemically verified using an inhibitory effect by 2.6 M urea in staining. Astrocytomas grades 3–4 and metastatic carcinomas were characterized by loss or marked reduction of stainability by urea treatment, while astrocytomas grades 1–2 and oligodendrogliomas were resistant to urea inhibition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401319
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  • 9
    Electronic Resource
    Electronic Resource
    Injection electroluminescence from CdTe p-n junctions prepared by LPE (1981)
    Springer
    Applied physics 26 (1981), S. 151-156 
    Details
    ISSN: 1432-0630
    Keywords: 78.60.Fi ; 73.40.Lq ; 81.10.Dn
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract CdTep-n junction diodes were prepared by LPE using CdCl2 as a solvent. Excess cadmium was added to the CdCl2-CdTe solution. Capacitance-voltage characteristics show that the diode structure is ofp-i-n type. Injection electroluminescence spectra reveal that radiative transitions occur mainly in thep-type region; relevant recombination centers are discussed in connection with those in a previous paper on the photoluminescence of CdTe:P crystals. Temperature dependences of the electroluminescence spectra were explained taking into account a change in sites where electrons radiatively recombine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00614749
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  • 10
    Electronic Resource
    Electronic Resource
    Meteoritic 138 Ce/ 142 Ce ratio and its evolution (1984)
    [s.l.] : Nature Publishing Group
    Nature 307 (1984), S. 251-252 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The experimental procedures used are almost identical to those of Tanaka and Masuda2. About 0.7 to 3 g of each sample was decomposed. Rare-earth elements (REE) were separated from the major elements by an AG50W-X8 resin column in HC1 media, while Ce and Nd were separated using an AG50W-X8 resin ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/307251a0
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