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  • 2005-2009  (81)
  • 1920-1924  (35)
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  • 1
    Book
    Book
    New York, NY :Springer,
    Title: Feasibility and infeasibility in optimization /; 118
    Author: Chinneck, John W.
    Publisher: New York, NY :Springer,
    Year of publication: 2008
    Pages: XXI, 270 S. : , graph. Darst.
    Series Statement: International series in operations research & management science 118
    ISBN: 0-387-74931-4 , 978-0-387-74931-0 , 978-0-387-74932-7
    Type of Medium: Book
    Language: English
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Inc
    Journal of the American Ceramic Society 88 (2005), S. 0 
    ISSN: 1551-2916
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A textured dielectric substrate for a broadband miniature antenna was fabricated using a thermoplastic green machining. This substrate comprised of three steps with optimized distribution of a dielectric ceramic (Bi–Ba–Nd–Titania; BBNT) and an epoxy. At first, a thermoplastic compound, consisting of BBNT particles and thermoplastic binders, was machined precisely using a mini-computer numeric controlled machine to make a three-dimensional void in the green BBNT body. After appropriate binder removal and sintering, the void in the dense BBNT block was filled with an epoxy to fabricate a textured dielectric substrate. The BBNT sample was characterized by several analyzing tools in terms of machinability, microstructural evolutions, chemical compositions, crystalline phase, and dielectric properties. Bandwidth and gain of the patch antenna with the textured dielectric substrate were measured and compared with the simulated results.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Inc
    Journal of the American Ceramic Society 88 (2005), S. 0 
    ISSN: 1551-2916
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A spatially variant dielectric Ca–Mg–silicate (CMS)/Bi–Ba–Nd–titania (BBNT) composite, in which periodic BBNT inclusions were embedded in the CMS matrix, was fabricated using the thermoplastic extrusion. The co-firing behavior of the composite was evaluated in terms of its shrinkage compatibility, thermoplastic compatibility, and chemical compatibility. The noticeable shrinkage mismatch between CMS and BBNT materials was observed. Such shrinkage mismatch strongly affected the interfacial bonding types of the composites. The good interfacial bonding was observed for the composite having BBNT inclusions in the CMS matrix; however, the interfacial cracking and matrix cracking for the opposite design (i.e., CMS inclusions in the BBNT matrix). In addition, the (Ca, Zn)-rich glassy phase in the CMS region migrated into the BBNT region, forming an interfacial reaction layer. The dielectric properties of the CMS, BBNT, and CMS–BBNT mixture were measured to evaluate the spatially variant dielectric CMS/BBNT composite as a novel dielectric substrate.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Fiscal studies 26 (2005), S. 0 
    ISSN: 1475-5890
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: This paper analyses the problem of water affordability in Great Britain. The use and meaning of the term ‘affordability’ are discussed in relation to the domestic or household customers of the British water industry. Using microeconomic data from the Family Resources Survey, affordability is calibrated by income group and household composition for Scotland, England and Wales. Whilst measurement or calibration is the primary focus of the paper, the related question of the way in which an affordability threshold or benchmark might be established is considered. A critique of the various financial support mechanisms currently available to households encountering difficulties in paying water and sewerage charges is followed by a discussion of the policy implications of the research and the way in which it relates to the wider social inclusion agenda of central government.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The molecular processes underlying alcohol dependence are not fully understood. Many characteristic behaviours result from neuroadaptations in the mesocorticolimbic system. In addition, alcoholism is associated with a distinct neuropathology. To elucidate the molecular basis of these features, we compared the RNA expression profile of the nucleus accumbens and prefrontal cortex of human brain from matched individual alcoholic and control cases using cDNA microarrays. Approximately 6% of genes with a marked alcohol response were common to the two brain regions. Alcohol-responsive genes were grouped into 11 functional categories. Predominant alcohol-responsive genes in the prefrontal cortex were those encoding DNA-binding proteins including transcription factors and repair proteins. There was also a down-regulation of genes encoding mitochondrial proteins, which could result in disrupted mitochondrial function and energy production leading to oxidative stress. Other alcohol-responsive genes in the prefrontal cortex were associated with neuroprotection/apoptosis. In contrast, in the nucleus accumbens, alcohol-responsive genes were associated with vesicle formation and regulation of cell architecture, which suggests a neuroadaptation to chronic alcohol exposure at the level of synaptic structure and function. Our data are in keeping with the previously reported alcoholism-related pathology characteristic of the prefrontal cortex, but suggest a persistent decrease in neurotransmission and changes in plasticity in the nucleus accumbens of the alcoholic.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Minocycline is neuroprotective in animal models of a number of acute CNS injuries and neurodegenerative diseases. While anti-inflammatory and anti-apoptotic effects of minocycline have been characterized, the molecular basis for the neuroprotective effects of minocycline remains unclear. We report here that minocycline and a number of antioxidant compounds protect mixed neuronal cultures in an oxidative stress assay. To evaluate the role of minocycline's direct antioxidant properties in neuroprotection, we determined potencies for minocycline, other tetracycline antibiotics, and reference antioxidant compounds using a panel of in vitro radical scavenging assays. Data from in vitro rat brain homogenate lipid peroxidation and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assays show that minocycline, in contrast to tetracycline, is an effective antioxidant with radical scavenging potency similar to vitamin E. Our findings suggest that the direct antioxidant activity of minocycline may contribute to its neuroprotective effects in some cell-based assays and animal models of neuronal injury.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Chemical reviews 23 (1923), S. 77-86 
    ISSN: 1520-6890
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Chemical reviews 23 (1923), S. 187-191 
    ISSN: 1520-6890
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 46 (1924), S. 903-917 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Berkeley, Calif. : Berkeley Electronic Press (now: De Gruyter)
    Journal of business valuation and economic loss analysis 2.2008, 2, art5 
    ISSN: 1932-9156
    Source: Berkeley Electronic Press Academic Journals
    Topics: Economics
    Notes: With the FASB's emphasis on fair value, valuation of privately held companies' capital structures has taken on additional emphasis. Each methodology proposed in the AICPA's Practice Aid "Valuation of Privately-Held-Company Equity Securities Issued as Compensation" can result in suboptimal valuations when valuing complex capital structures. We discuss valuation of such capital structures and offer a workable, integrated simulation methodology combining the strengths of the probability-weighted expected return method with those of the option-pricing method. We demonstrate the methodology using transformed real-world data resulting in a flexible methodology that can be expanded to accommodate various aspects of complex capital structures.
    Type of Medium: Electronic Resource
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