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  • 2005-2009  (23)
Material
Year
Person/Organisation
Language
  • 1
    Book
    Book
    Providence, RI :American Mathematical Soc.,
    Title: Large deviations for stochastic processes /; 131
    Author: Feng, Jin
    Contributer: Kurtz, Thomas G.
    Publisher: Providence, RI :American Mathematical Soc.,
    Year of publication: 2006
    Pages: XII, 410 S.
    Series Statement: Mathematical surveys and monographs 131
    ISBN: 0-8218-4145-9 , 978-0-8218-4145-7
    Type of Medium: Book
    Language: English
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  • 2
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Central neuropathic pain (CNP) is an important problem following spinal cord injury (SCI), because it severely affects the quality of life of SCI patients. As in the patient population, the majority of rats develop significant allodynia (CNP rats) after moderate SCI. However, about 10% of SCI rats do not develop allodynia, or develop significantly less allodynia than CNP rats (non-CNP rats). To identify transcriptional changes underlying CNP development after SCI, we used Affymetrix DNA microarrays and RNAs extracted from the spinal cords of CNP and non-CNP rats. DNA microarry analysis showed significantly increased expression of a number of genes associated with inflammation and astrocytic activation in the spinal cords of rats that developed CNP. For example, mRNA levels of glial fibrilary acidic protein (GFAP) and Aquaporin 4 (AQP4) significantly increased in CNP rats. We also found that GFAP, S100β and AQP4 protein elevation persisted for at least 9 months throughout contused spinal cords, consistent with the chronic nature of CNP. Thus, we hypothesize that CNP development results, in part, from dysfunctional, chronically “over-activated” astrocytes. Although, it has been shown that activated astrocytes are associated with peripheral neuropathic pain, this has not previously been demonstrated in CNP after SCI.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Lincoln, Neb. : Berkeley Electronic Press (now: De Gruyter)
    Journal of agricultural & food industrial organization 5.2007, 1, art10 
    ISSN: 1542-0485
    Source: Berkeley Electronic Press Academic Journals
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Economics
    Notes: With increasing interest in renewable energy from agriculture, including biopower and cellulose ethanol, there is a need for better understanding of the economic organization of this emerging industry. Study of the organization of the biopower industry represents an under-researched area and a new application of transaction cost theory to an emerging industry. Refinement of the theory can also result from challenging applications. This article provides an application of transaction cost economics to the existing United States biopower industry while challenging the empirical convention of excluding production cost variables from transaction cost analysis. Utilizing survey data from 53 biopower generators we study the relationship between physical asset specificity, site specificity, and scale in explaining firms' decisions to procure inputs internally, externally, or to use both methods. Consistent with transaction cost theory, both site specificity and scale are good predictors of organizational form. Given this evidence, this article reconsiders the impact of scale and transaction costs on the choice of organizational from.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the American Water Resources Association 41 (2005), S. 0 
    ISSN: 1752-1688
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Notes: : High springtime river flows came earlier by one to two weeks in large parts of northern New England during the 20th Century. In this study it was hypothesized that late spring/early summer recessional flows and late summer/early fall low flows could also be occurring earlier. This could result in a longer period of low flow recession and a decrease in the magnitude of low flows. To test this hypothesis, variations over time in the magnitude and timing of low flows were analyzed. To help understand the relation between low flows and climatic variables in New England, low flows were correlated with air temperatures and precipitation. Analysis of data from 23 rural, unregulated rivers across New England indicated little evidence of consistent changes in the timing or magnitude of late summer/early fall low flows during the 20th Century. The interannual variability in the timing and magnitude of the low flows in northern New England was explained much more by the interannual variability in precipitation than by the interannual variability of air temperatures. The highest correlation between the magnitude of the low flows and air temperatures was with May through November temperatures (r =−0.37, p= 0.0017), while the highest correlation with precipitation was with July through August precipitation (r = 0.67, p 〉 0.0001).
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing
    The @journal of child psychology and psychiatry 46 (2005), S. 0 
    ISSN: 1469-7610
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Background:  The area of child custody assessments continues to fail to meet the evidence-based threshold now established in clinical practice. This is despite the existence, for many years, of published guidelines governing the practice of custody assessments available from a number of professional bodies.Methods:  This article reviews the potential of attachment theory to contribute to the conceptualization of custody evaluations, clinical assessment, and the development of evidence-based practice. Particular attention is paid to specific instruments used to assess attachment in clinic and non-clinic settings.Results:  Guidelines concerning child custody assessments highlight the particular importance of assessing attachment and parent–child relationship quality. However, measures often used in the course of a custody assessment are not backed up with empirical research, and the measures that are supported by empirical research have been slow to influence practice. There may be conceptual and measurement advantages of considering an attachment research-informed custody assessment.Discussion:  Attachment theory has obvious conceptual relevance for the child custody context. Further clinical research is needed to demonstrate the usefulness of attachment research measures; research of this kind may shed important light on the development and resilience of affectional bonds.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1365-2826
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Signal transducers and activators of transcription (STATs) are a family of transcription factors linked to class I cytokine receptors. In the present study, we investigated whether their distribution in the hypothalamus reflects the feedback regulation by growth hormone and what role they might play in the functioning of target neurones. We demonstrate that each of the seven known STATs has a distinct distribution in the hypothalamus. Notably, the STAT5 proteins, that are important in growth hormone (GH) and prolactin signalling in peripheral tissues, were expressed in somatostatin neurones of the periventricular nucleus and dopamine neurones of the arcuate nucleus. Because somatostatin neurones are regulated by feedback from circulating GH, we investigated the importance of STAT5 in these neurones. We demonstrate that STAT5b protein expression, similar to somatostatin mRNA, is sexually dimorphic in the periventricular nucleus of rats and mice. Furthermore, chronic infusion of male dwarf rats with GH increased the expression of STAT5b, while a single injection of GH into similar rats induced the phosphorylation of STAT5 proteins. The cellular abundance of somatostatin mRNA in STAT5b-deficient mice was significantly reduced in the periventricular nucleus, effectively reducing the sexually dimorphic expression. These results are consistent with the hypothesis that STAT5 proteins are involved in the feedback regulation of somatostatin neurones by GH, and that these neurones may respond to patterned GH secretion to reinforce sexual dimorphism in the GH axis.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 60 (2005), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Melbourne, Australia : Blackwell Science Pty
    International journal of urology 12 (2005), S. 0 
    ISSN: 1442-2042
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract  Inflammatory pseudotumors are a rare entity, the etiology of which is not well understood. It has been postulated that these non-neoplastic lesions are the result of a reaction to trauma, surgery, infection or local irritation, though in many cases an underlying cause is never found. In this case, a 30-year-old man with previously undiagnosed human immunodeficiency virus presented with a 2-week history of painless right testicular mass measuring 1 × 1 cm. The patient underwent right radical orchiectomy with histopathological analysis revealing an inflammatory pseudotumor of the testis. Further work up pointed to acute retroviral syndrome as the likely cause.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd.
    Bioethics 19 (2005), S. 0 
    ISSN: 1467-8519
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Philosophy
    Notes: Clear guidelines addressing the ethically appropriate use of anti-infectives in the setting of hospice care do not exist. There is lack of understanding about key treatment decisions related to infection treatment for patients who are eligible for hospice care. Ethical concerns about anti-infective use at the end of life include: (1) delaying transition to hospice, (2) prolonging a dying process, (3) prescribing regimens incongruent with a short life expectancy and goals of care, (4) increasing the reservoir of potential resistant pathogens, (5) placing unreasonable costs on a capitated hospice system. Although anti-infectives are thought to be relatively safe, they can place a burden on patients and be inconsistent to particular care plans. The current complex, and at times fragmented, medical care often fails to address these issues in decision-making. In many ways, the ethics governing the end of life decisions related to dialysis, hydration/nutrition, and hypercalcemia parallel those of anti-infectives. In this article we articulate important elements in ethical decision-making in the application of anti-infectives for patients who are eligible for hospice care, and we point to the need for prospective studies to help refine particular guidelines in these cases.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK; Malden, USA : Blackwell Publishing Ltd/Inc.
    New blackfriars 86 (2005), S. 0 
    ISSN: 1741-2005
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Theology and Religious Studies
    Type of Medium: Electronic Resource
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