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  • 11
    Electronic Resource
    Electronic Resource
    A double-blind randomized vehicle-controlled clinical trial investigating the effect of ZnPTO dose on the scalp vs. antidandruff efficacy and antimycotic activity (2003)
    Oxford, UK : Blackwell Science, Ltd
    International journal of cosmetic science 25 (2003), S. 0 
    Details
    ISSN: 1468-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Dandruff is a common problem in approximately 30% of the world's population. Reports in the literature regarding treatment of this condition with various antidandruff shampoos usually report the level of active ingredient within the formulation. However, we propose that a more important parameter relating to antidandruff efficacy is the amount of active ingredient delivered to the scalp from the shampoo. This report describes the results from two studies designed to investigate the relationship between the level of zinc pyrithione (ZnPTO) deposited onto the scalp and the resultant scalp condition. A double-blind randomized vehicle-controlled clinical study comparing three shampoos – a vehicle, a low-depositing ZnPTO shampoo and a high-depositing ZnPTO shampoo – was carried out in the U.K. with 53 panelists with dandruff or mild-to-moderate seborrheic dermatitis of the scalp. Both shampoos containing ZnPTO were significantly superior in antidandruff efficacy to the vehicle. Furthermore, the high-depositing ZnPTO shampoo was significantly superior compared with the low-depositing ZnPTO shampoo in terms of both antidandruff efficacy and antimycotic activity. Antidandruff performance and antimycotic activity of ZnPTO-containing shampoos is highly dependent on the amount of active ingredient delivered to the scalp. Furthermore, careful manipulation of the formulation parameters of an antidandruff shampoo can result in enhanced levels of delivery of the active ingredient without having to increase the level of active ingredient within the formulation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1467-2494.2003.00183.x
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  • 12
    Electronic Resource
    Electronic Resource
    SCANNING ELECTRON MICROSCOPY IN THE STUDY OF CERVICAL NEOPLASIA (1971)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 78 (1971), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Scanning electron microscopy has been used to study normal and abnormal cervical epithelia. Normal columnar epithelium and normal squamous epithelium have been identified and described. Carcinoma in situ has also been examined and characteristic differences in tissue organization and cell morphology have been recognized. The surfaces of normal squamous cells are arranged with interconnecting microridges, whereas the surface epithelium from carcinoma in situ cells is arranged in closly packed microvilli. The significance of these results and the possible potential of the technique in studying the natural history of carcinoma in situ are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1971.tb00209.x
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  • 13
    Electronic Resource
    Electronic Resource
    T-Cell Receptor V-Region Usage and Antigen Specificity (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 756 (1995), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1995.tb44477.x
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  • 14
    Electronic Resource
    Electronic Resource
    INCREASING THE VALUE OF MANAGEMENT APPRAISAL SCHEMES: AN ORGANIZATIONAL LEARNING APPROACH (1970)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of management studies 7 (1970), S. 0 
    Details
    ISSN: 1467-6486
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1467-6486.1970.tb00479.x
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  • 15
    Electronic Resource
    Electronic Resource
    ESR of the BH4 molecule in solid hydrogen (1997)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 107 (1997), S. 4756-4759 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: BH4, with isotopic substitution, has been prepared and trapped in solid H2, D2, HD by laser vaporization of boron and subsequent reaction with the matrix gas. The results confirm the C2v structure of the molecule and generally support the results of Symons et al., on γ-irradiated NaBH4. Differences from those results are discussed, and comparison is made with the CH4+ parameters of Knight et al.© 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.474838
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  • 16
    Electronic Resource
    Electronic Resource
    Water-deficit-induced translational control in Nicotiana tabacum (2003)
    Oxford, UK : Blackwell Science, Ltd
    Plant, cell & environment 26 (2003), S. 0 
    Details
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The effect of prolonged water deficit on mRNA translation was quantitatively analysed in apical and basal leaves of whole tobacco (Nicotiana tabacum) plants. The level of large polysomes (six or more ribosomes per mRNA) was significantly higher in apical than basal leaves under well-watered conditions. In both young and old leaves, water deficit caused a progressive reduction in levels of polysomes with concomitant increases in 80S monosomes, indicative of reduced initiation of translation. Despite the global reduction in polysome formation over 144 h of water deficit, the water-deficit-induced putative lipid transfer protein (ltp) mRNA was associated with large polysomes and LTP content increased. Osmotin (osm) mRNA, another water-deficit-induced transcript, also remained associated with large polysomes during prolonged water deficit. In contrast, mRNAs encoding the non-stress proteins ribulose bisphosphate carboxylase/oxygenase small subunit (rbcS) and eukaryotic initiation factor 4A (eIF4A) decreased in abundance and shifted to small polysomes and non-polysomal complexes, indicating that initiation of translation of these mRNAs was impaired by water deficit. These results show that translational regulation is a component of the water-deficit response and the differential translation of individual mRNAs is distinct in leaves of different age.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3040.2003.00952.x
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  • 17
    Electronic Resource
    Electronic Resource
    The Effect of Mildew and Leaf Blotch on Yield and Quality of cv. Lior Italian Ryegrass (1970)
    Oxford, UK : Blackwell Publishing Ltd
    Plant pathology 19 (1970), S. 0 
    Details
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: A measurement of the effect of mildew and leaf blotch on both yield and quality of Lolium multiflorum (cv. Lior) was undertaken in two trials sown in 1966 and 1967.Plots were sprayed with a fungicide at 10-day intervals, and four cuts were taken during the season. Disease assessments were made at the time of cutting. Considerable differences in yield and quality were recorded which could be broadly related to the levels of disease infection in the treatments.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3059.1970.tb01001.x
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  • 18
    Electronic Resource
    Electronic Resource
    Solving inequities in provider distribution: loan repayment (2002)
    Oxford, UK : Blackwell Science Ltd
    Health & social care in the community 10 (2002), S. 0 
    Details
    ISSN: 1365-2524
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The distribution of primary health care professionals in England and Wales is inequitable, with relatively lower concentrations of professionals in deprived areas. The objective of the present study was to determine whether graduate health professionals would be willing to work in under-served areas in return for educational loan repayment. The study group consisted of a convenience sample of 50 newly qualified and trainee general practitioners, and 50 newly qualified community nurses and health visitors in mid- and west Wales. At interview, the subjects were presented with descriptions of general practices and asked to indicate their preferred practice. Practice descriptions varied systematically in terms of location (i.e. urban, suburban and rural), population deprivation (i.e. deprived or mixed affluent/deprived) and availability of loan repayment (i.e. none or loans paid off over a period of between one and 4 years). The main outcome was the probability that a practice with loan repayment was chosen. Compared with a suburban practice, a one-year loan repayment option made the rural and urban deprived practices 1.6 times and 1.2 times more likely to be chosen, respectively. Nurses were generally more willing than doctors to work in a deprived area in return for loan repayment. The findings suggest that loan repayment may offset health professionals’ aversion to working in deprived areas. Such a scheme needs to be piloted to see whether it does offer value for money in recruiting health professionals to under-served areas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2524.2002.00354.x
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  • 19
    Electronic Resource
    Electronic Resource
    The use of Fourier descriptors in the classification of particle shape (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Sedimentology 42 (1995), S. 0 
    Details
    ISSN: 1365-3091
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: A new quantitative method for characterizing quartz grain shape is presented. The method employs a harmonic analysis based upon Fourier descriptors which is a distinct variation of the traditional and widely used Fourier series. Quartz grain images from a scanning electron microscope were ‘frame grabbed’and converted to a digitized grey-level image. The image processing techniques of enhancement, segmentation and boundary tracking were applied to remove all features except the image boundary. This boundary was sampled at uniform intervals of are length and represented mathematically on the complex plane. In this way problems associated with the location of particle centroid and re-entrant values were avoided. The resulting data was standardized relative to scale, rotation and starting position. Hence the discrete Fourier transform was applied using modern fast Fourier transform techniques and the modulus of the resulting harmonic amplitude used to characterize the grain shape. The technique was applied to a sample of 0–5-m quartz grains from three distinct populations: desert quartz, beach grains (Fire Island, New York) and Brazilian crushed quartz. Whilst plots of average amplitude vs. harmonic number for each population appeared similar, discriminant analysis applied to each grain sample distinguished characteristic grain shape with an excellent degree of success. The problems of location of the centroid and re-entrant values were eliminated. This allowed the technique to be applied to a much wider group of irregularly shaped sedimentary particles such as loess.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3091.1995.tb00397.x
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  • 20
    Electronic Resource
    Electronic Resource
    The effect of additives on the ensilage of forage of differing perennial ryegrass and white clover content (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Grass and forage science 50 (1995), S. 0 
    Details
    ISSN: 1365-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Pure perennial ryegrass or perennial ryegrass/white clover mixtures (70:30 and 40:60 on a fresh-matter basis) were ensiled in laboratory silos either untreated or alter treatment with freshly cultured Lactobacillus (Lb.) plantarun or freshly cultured Lb. plantarum plus Lactococcus (Lc.) lactis. freeze-dried Lb. plantarum or freeze-dried Lb. Plantarum plus sodium formate, sodium formate or formic acid. The effect of these additives on silage fermentation characteristics and quality of the resultant silages was examined. There were significant interactions between treatments and herbages for all silage quality parameters measured, except for acetic acid concentration. The influence of additives on the final pH of all silages was small but statistically significant. Lactic acid concentration was not directly related to herbage mixture, overall mean values ranging from 118 to 120 ± 1.5 g kg−1 dry matter (DM), but wider variation was seen between treatments for individual herbage mixtures. Acetic acid concentrations were significantly (P〈0·001) affected by herbage mixture ensiled, increasing linearly as clover content increased from zero to 60%. Untreated control and formic acid-treated silages contained significantly (p〈0·001) higher acetic acid concentrations than those treated with other additives. Silage ammonia N concentrations were significantly (p〈0 001) influenced by herbage mixture. Lowest ammonia N concentrations (〈 50 g kg−1 DM) were observed in silages that had been treated with formic acid, freshly cultured Lb. plantarum or Lb. plantarum plus Lc. lactis. The fraction 1 leaf protein (FILP) contents of silages were significantly (P 〈0·001) affected by both treatment and herbage mixture, with consistently and significantly higher values found in freshly cultured inoculant-treated silages. A poor correlation (r2= 0·12) existed between ammonia N and FILP in all silages. The inclusion of up to 60% white clover in the ensiled herbage did not adversely affect final silage quality. However, additive treatment markedly influenced the residual FILP content of silages, those treated with freshly cultured inoculants having the highest values.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2494.1995.tb02320.x
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