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  • 1
    Electronic Resource
    Electronic Resource
    Femtosecond four wave mixing spectroscopy of conjugated polymers (1993)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 99 (1993), S. 1597-1606 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Time-resolved four wave mixing (4WM) signals of conjugated polymers are calculated using a density matrix approach and the Hartree–Fock approximation. The influence of the Coulomb interaction as well as size effects on the nonlinear optical response are examined. For the Hückel model (no Coulomb interaction), quantum beats due to the coherent excitation of several band states are found for small sizes, and photon echo-like behavior is obtained for infinite size. The Coulomb interaction changes the nature of the response and gives rise to a broad delayed signal whose temporal profile is determined by the dephasing time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.465328
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  • 2
    Electronic Resource
    Electronic Resource
    Topical treatment of common warts in an HIV-positive patient with imiquimod 5% cream (2003)
    Oxford, UK : Blackwell Publishing
    Clinical and experimental dermatology 28 (2003), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary Human immunodeficiency virus (HIV) infects and destroys crucial components of the immune system, leaving patients susceptible to a number of viral, bacterial and fungal diseases. Viral warts are caused by human papillomavirus infection and are a common skin disease that afflicts HIV-infected patients. Treatment modalities currently rely on destruction of the infected tissue or interruption of cell division; however, frequent recurrence is a particular challenge in HIV-infected patients. We report the case of a 41-year-old HIV-positive man with multiple common warts located on his hands and feet. Following 5 months of treatment with imiquimod, an immune response modifier, as a 5% cream, complete clearance of all warts was achieved. Mild erythma, itching and burning at the application site was observed in the early stages of treatment. The patient showed no relapse of warts at the 30-month follow-up visit.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2230.28.s1.16.x
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  • 3
    Electronic Resource
    Electronic Resource
    PANTOPRAZOLE AND 24-HOUR INTRAGASTRIC ACIDITY (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 7 (1993), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2036.1993.tb00077.x
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  • 4
    Electronic Resource
    Electronic Resource
    Single intravenous administration of the H+, K+-ATPase inhibitor BY 1023/SK&F 96022—inhibition of pentagastrin-stimulated gastric acid secretion and pharmacokinetics in man (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 4 (1990), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The effects of the H+, K+-ATPase inhibitor BY 1023/SK&F 96022 on pentagastrin-stimulated acid secretion have been studied in healthy male volunteers (n= 12). The gastric acid response to submaximal pentagastrin-stimulation (0.6 μg/h/kg b.w.) was dose-dependently inhibited. A single dose of 5 mg decreased acid output by 22% while after 60 mg and 80 mg secretion was almost completely abolished.A good dose linearity was observed for AUC (0, 〉) and Cmax over the dose range from 5 to 80 mg. Elimination half-life, total clearance and volume of distribution of the parent compound were independent of the dose.The drug was well tolerated up to the highest dose of 80 mg. No clinically relevant influence was found on either laboratory screen or cardiovascular parameters.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2036.1990.tb00468.x
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  • 5
    Electronic Resource
    Electronic Resource
    Elevated expression of extracellular matrix metalloproteinase inducer (CD147) and membrane-type matrix metalloproteinases in venous leg ulcers (2002)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 147 (2002), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary Background  Matrix metalloproteinases (MMPs) contribute to matrix remodelling in venous leg ulcers. Extracellular MMP inducer (EMMPRIN; CD147) has been reported to increase MMP expression, and membrane type 1 MMP (MT1-MMP) has been implicated in the activation of MMPs. Objectives  To examine whether and to what degree EMMPRIN, MMP-2, MT1-MMP and membrane type 2 MMP (MT2-MMP) are expressed in venous leg ulcers as well as the association with MMP activity. Methods  EMMPRIN, MMP-2, MT1-MMP and MT2-MMP were analysed by zymography and immunohistochemistry in biopsies from healthy skin and lesional tissue from venous leg ulcers. Results  Zymography provided direct evidence of increased proteolytic activity of MMP-2 in lesional skin in comparison with healthy controls. Immunostaining showed intense expression of EMMPRIN, MMP-2, MT1-MMP and MT2-MMP in dermal structures of venous leg ulcers, whereas only EMMPRIN and MMP-2 showed elevated expression in perivascular regions. Our findings indicate that venous leg ulcers are characterized by elevated expression of EMMPRIN, MMP-2, MT1-MMP and MT2-MMP. The immunohistological findings of skin alterations reflect the dynamic process of activation of soluble and membrane-bound MMPs, which may be highly induced by EMMPRIN. Conclusions  These data suggest for the first time that membrane-bound MMPs may favour enhanced turnover of the extracellular matrix and support unrestrained MMP activity in venous leg ulcers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2002.05025.x
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  • 6
    Electronic Resource
    Electronic Resource
    A topological characterization for closed sets under polar duality in ℚ n (1990)
    Springer
    Mathematical programming 49 (1990), S. 281-283 
    Details
    ISSN: 1436-4646
    Keywords: Linear duality ; polar duality ; closed sets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract A topological characterization is given for closed sets in ℚ n under the restriction of (cone) polar duality to ℚ n .
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01588793
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  • 7
    Electronic Resource
    Electronic Resource
    Detection of damaged membranes in alkali chloride electrolysers (1994)
    Springer
    Journal of applied electrochemistry 24 (1994), S. 1201-1205 
    Details
    ISSN: 1572-8838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Notes: Abstract Holes in cation exchange membranes of alkali chloride cells can have a number of different causes. They do not represent a source of great danger during operation of a membrane electrolyser as long as their number is limited or their combined diameter does not exceed a certain size. Of the different methods for detection of holes in membranes, two procedures are described in detail: the cell voltage test and the leak test with measurement of the gas flow through the holes. The cell voltage test is performed with low time consumption during start-up of an electrolyser. It mainly shows the large membrane holes in a cell. In contrast to this, with the leak test all holes in a membrane are detected. However, the procedure is time consuming and is possible only with a totally drained electrolyser. It is recommended to perform these tests immediately after installing new membranes and then from time to time in order to avoid damage to the cells or to the plant chlorine system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00249882
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  • 8
    Electronic Resource
    Electronic Resource
    Chlorate and oxygen formation in alkali chloride membrane electrolysis (1993)
    Springer
    Journal of applied electrochemistry 23 (1993), S. 103-107 
    Details
    ISSN: 1572-8838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Notes: Abstract During the operation of an industrial-scale membrane electrolysis plant over a number of years, a record was kept of the formation of the byproduct oxygen in the anode gas and chlorate in the anolyte parallel to the decline of the current efficiencies of the main products. It was found that the current efficiencies of the byproducts increase linearly with the declining current efficiencies of the main products, chlorine and caustic soda. Of the two types of anode used, one exhibited considerably more oxygen formation than the other. The high-oxygen anode was associated with distinctly lower chlorate formation than the low-oxygen anode. The increasing oxygen contents and chlorate formation rates associated with falling caustic current efficiency are reported for both types of anode. If hydrochloric acid is used to destroy the chlorate, the amount of acid must be increased as the caustic current efficiency falls. The amounts of hydrochloric acid required for the two types of anode are calculated as examples for 96% and 93% caustic current efficiency.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00246945
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  • 9
    Electronic Resource
    Electronic Resource
    Defect generation in polycrystalline Cu(In,Ga)Se2 by high-energy electron irradiation (2000)
    Springer
    Applied physics 70 (2000), S. 677-680 
    Details
    ISSN: 1432-0630
    Keywords: PACS: 61.80.Fe; 61.82.Fk; 84.60.Jt
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract. We investigate the degradation of ZnO/CdS/ Cu(In,Ga)Se2 heterojunction solar cells for space applications and the defect generation in polycrystalline Cu(In,Ga)Se2 thin films by irradiation with 1-MeV electrons with fluences φe up to φe=5×1018 cm-2. Notable degradation of the solar cell performance starts at fluences of φe=1017 cm-2 where the open circuit voltage decreases by about 5% while short circuit current and fill factor remain essentially unaffected. Thus, Cu(In,Ga)Se2 solar cells withstand electron fluences which are higher by one order of magnitude or more when compared to other technologies. A model describes the absolute open circuit voltage loss considering the increase of space charge recombination by electron irradiation-induced defects. Defect analysis by admittance spectroscopy shows that acceptor defects with an energy distance of approximately 300 meV from the valence band are generated at a rate γ=0.017 (±0.01) cm-1.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003390050014
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  • 10
    Electronic Resource
    Electronic Resource
    Theoretical exploration of stationary and of ultrafast spectroscopy of small clusters (2000)
    Springer
    Applied physics 71 (2000), S. 343-349 
    Details
    ISSN: 1432-0649
    Keywords: PACS: 31.15Ar; 31.15Qg; 31.50+w
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. Stationary spectra offer information on the interplay between the structures and the nature of electronic excitations reflecting bonding properties, as shown by comparing Sin with Agn (n=4-6) clusters. In order to study the dynamical properties, simulations and analysis of femtosecond (fs) time-resolved pump–probe or pump–dump signals have been carried out, which allows us to determine the timescales and the nature of configurational changes versus internal vibrational relaxation (IVR) in electronic ground or excited states. For this purpose we have developed a multi-state ab initio molecular dynamics (involving ground as well as adiabatic or non-adiabatic excited electronic states) on the timescale of the nuclear motion, using the time evolution of a thermal ensemble in the Wigner representation. The combination of ab initio quantum-chemical methods used for the molecular dynamics ‘on the fly’ and the Wigner-distribution approach for the description of the motion of the nuclei also allowed the accurate determination of pump–probe and pump–dump signals under temperature-dependent initial conditions. We use this novel combination of methods to investigate the dynamics in excited states of non-stoichiometric NanFn-1 clusters with a single excess electron. The timescales of the structural relaxation in excited states versus intramolecular vibrational relaxation processes have been determined, as illustrated for the example of Na4F3. This is the first study of the system with 15 degrees of freedom for which the dynamics in the excited states has been carried out without the precalculation of the energy surfaces.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00006967
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