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Ion cyclotron resonance in a magnetized sheet plasma : Proceedings of 5th international conference on ion sources (1994)

Nanri, K. ; Matsumura, M. ; Homma, M. ; [et al.]

[S.l.] : American Institute of Physics (AIP)

Review of Scientific Instruments 65 (1994), S. 1359-1361

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ISSN: 1089-7623

Source: AIP Digital Archive

Topics: Physics , Electrical Engineering, Measurement and Control Technology

Notes: Separation of ionic or isotopic species in a magnetized sheet plasma has been studied by using the ion cyclotron resonance method. The sheet plasma was used instead of a cylindrical plasma in which many unfavorable collisions take place. An rf electric field is applied to the plasma by two parallel plate electrodes. It is shown that a resonance is strongly dependent on the plasma space potential across the sheet plasma. The resonance spectra of argon, neon, and nitrogen ions in the low dense sheet plasma with a shallow potential well are clearly observed, while the resonances in high dense plasma with a deep potential well are not observed. It is also found that the resonance frequency for a corresponding ion is proportional to the magnetic field strength.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1063/1.1144960

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Identification of 187 single nucleotide polymorphisms (SNPs) among 41 candidate genes for ischemic heart disease in the Japanese population (2000)

Ohnishi, Y. ; Tanaka, T. ; Yamada, R. ; [et al.]

Springer

Human genetics 〈Berlin〉 106 (2000), S. 288-292

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ISSN: 1432-1203

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Abstract. To investigate whether common variants in the human genetic background are associated with pathogenesis of ischemic heart diseases, we systematically surveyed 41 possible candidate genes for single-nucleotide polymorphisms (SNPs) by directly sequencing 96 independent alleles at each locus, derived from 48 unrelated Japanese patients with myocardial infarction, including 25.8 kb 5' flanking regions, 56.8 kb exonic and 35.4 kb intronic sequences, and 1.8 kb 3' flanking regions. In this genomic DNA of nearly 120 kb, we identified 187 SNPs: 55 in 5' flanking regions, seven in 5' untranslated regions (UTRs), 52 in coding elements, 64 in introns, eight in 3' UTRs, and one in a 3' flanking region. Among the 52 coding SNPs, 26 were non-synonymous changes. Allelic frequencies of some of the polymorphisms were significantly different from those reported in European populations. For example, the Q506R substitution in the coagulation factor V gene, the so-called "Leiden mutation", has a reported frequency of 2.3% in Europeans, but we detected the Leiden mutation in none of the Japanese genomes that we investigated. The allelic frequencies of the –33A〉G SNP in the thrombomodulin gene were also very different; this allele occurred at a 12% frequency in the Japanese patients that we examined, although it had been detected in none of 82 Caucasians reported previously. These data support the hypothesis that some SNPs are specific to particular ethnic groups.