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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 361 (1983), S. 581-583 
    ISSN: 1435-2451
    Keywords: Pheochromocytoma ; Cardiovascular disorders ; Adrenergic blockade ; Endocrine surgery ; Phäochromocytom ; Perioperative Komplikation ; Catecholaminblockade ; Endokrine Chirurgie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Wirkung von prä- und intraoperativ appliziertenα-bzw.β-Receptoren-blockern auf die perioperative Komplikationsrate beim Phäochromocytom wurde an Hand von 21 eigenen Fällen untersucht. Die Vorbehandlung mitα- bzw.β-Blockern führte nur zu einer subtotalen Blockade der Catecholaminwirkung. Die intraoperativen Kreislaufdysregulationen waren aber abgeschwächt und nach Gabe vonα- bzw.β-Blockern rasch reversibel. Durch gezielte intra- und postoperative Volumenzufuhr gelang es, postoperative hypotone Phasen weitgehend zu verhindern. Die perioperative Letalität konnte durch dieses Behandlungskonzept auf 0% gesenkt werden.
    Notes: Summary The effect of pre- and intraoperativeα- andβ-adrenergic blockade on cardiovascular disorders in patients with pheochromocytoma was studied. Catecholamine responses during surgery were not totally eliminated by pretreatment with a- and ß-blocking drugs. Intraoperative changes in blood pressure and cardiac rhythm, however, were attenuated and could be easily controlled byα- andβ-blocking drugs or sodium nitroprussid and xylocain. Severe postoperative hypotension was efficiently prevented by judicious intra- and postoperative volume replacement. Postoperative mortality could be reduced to 0% by this perioperative treatment.
    Type of Medium: Electronic Resource
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