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  • 1
    Electronic Resource
    Electronic Resource
    EFFECT OF INTRAVENTRICULAR INJECTION OF 5,7-DIHYDROXYTRYPTAMINE ON SERUM GONADOTROPINS AND PROLACTIN (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 305 (1978), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1978.tb31539.x
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  • 2
    Electronic Resource
    Electronic Resource
    Morphological features of physiologically identified hypothalamic neurons as revealed by intracellular marking (1979)
    Springer
    Experimental brain research 34 (1979), S. 107-116 
    Details
    ISSN: 1432-1106
    Keywords: Parvocellular hypothalamic neurons ; Neurosecretion ; In vitro preparation ; Procion yellow ; Intracellular
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In the in vitro slice preparation intracellular recordings and injections of procion yellow (PY) were made in neurons of the hypothalamus. Of these neurons, one medial preoptic-anterior hypothalamus (MPO-AH) and four arcuate-ventromedial hypothalamus (ARC-VM) neurons were driven by electrical stimulation of the median eminence area (ME). Two other MPO-AH and five other ARC-VM neurons were driven by stimulation of the stria terminalis (ST). On the basis of the PY injections two morphologically distinct cell types were delineated: a larger multipolar cell type with a polygonal perikaryon was found with equal frequency in the MPO-AH and the ARC-VM. A smaller fusiform cell type was encountered mainly in the ARC-VM. On the secondary dendrites of both cell types spine-like appendages were seldom seen, but dendritic swellings were common. Some of the dendrites projected to capillaries in both areas and presumably contacted them. The axons were usually tortuous and could only be traced a short distance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00238344
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  • 3
    Electronic Resource
    Electronic Resource
    Effects of chemical lesion of the ventral noradrenergic bundle or of the medial preoptic area on preovulatory LH release in rats (1979)
    Springer
    Experimental brain research 35 (1979), S. 127-134 
    Details
    ISSN: 1432-1106
    Keywords: Chemical lesion ; Ventral noradrenergic bundle ; Medial preoptic area ; Preovulatory LH release
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The noradrenergic innervation of the medial preoptic area (MPO) and the hypothalamus is provided by mesencephalic neurons via the ventral noradrenergic tract. Fibers of these neurons emerge through the MPO. Bilateral microinjections of 6-OHDA into the ventral noradrenergic bundle (VNB) depletes large parts of the diencephalon of norepinephrine (NE) and dopamine (DA). Since the total hypothalamic DA content is of intrahypothalamic origin, 6-OHDA injection into the VNB does not reduce hypothalamic DA content. Similarly microinjections of 6-OHDA into the MPO reduces hypothalamic and preoptic NE content without altering NE concentrations in other diencephalic structures. Microinjections of 6-OHDA and of the carrier solution of 6-OHDA into the VNB or into the MPO of female rats with regular estrous cycles results in a slight disturbance of the cyclic activity for few days. Within 1–4 days normal cyclic activity is resumed. Preovulatory LH release is substantially reduced 8–12 days after injection of 6-OHDA into the VNB or into the MPO. On the basis of these and previous results it is concluded that the availability of NE in the MPO is an important factor in determining the hight of the preovulatory LH surge.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00236789
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  • 4
    Electronic Resource
    Electronic Resource
    Response of medial preoptic neurons to electrical stimulation of the mediobasal hypothalamus, amygdala and mesencephalon in normal, serotonin or catecholamine deprived female rats (1975)
    Springer
    Experimental brain research 22 (1975), S. 495-507 
    Details
    ISSN: 1432-1106
    Keywords: Preoptic unit activity ; Stimulation of mesencephalon ; Amygdala ; Mediobasal hypothalamus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Single cell activity from preoptic neurons was extracellularly recorded in normal female rats and the effects of electrical stimulation of the mediocortical amygdala (AMY), the N. med. raphes (MES) and the mediobasal hypothalamus (MBH) was tested. 1. One type of preoptic neurons (55%) reacted with primary excitation to a single electrical stimulus of AMY, MES or MBH, which was usually followed by a period of postexcitatory inhibition. Another type of neurons (29%) were first inhibited after stimulation of AMY, MES or MBH and then showed a period of postinhibitory excitation. The discharge rate of a third type was not affected by electrical stimulation of these structures (16%). If a neuron was affected by a stimulus in a given area it predictably reacted in the same fashion to stimulation of the other areas. 2. The postexcitatory inhibition of the majority of the primarily excited neurons was strong enough to prevent the stimulus response to a second stimulus. Occasional recordings from two neighboured cells simultaneously indicate that they can be inhibitory to each other. 3. By pulse train stimulation of the AMY or MES with varying frequencies it could be demonstrated that low frequencies (10 Hz) had a facilitatory action whereas higher frequencies (100 Hz) were inhibitory to preoptic discharge rates. 4. No obvious alteration of neuronal properties we found neither in rats treated intraventricularly with 5,6-dihydroxytryptamine, which strongly reduces central nervous system serotonin content, nor in 6-hydroxydopamine treated rats, which had low central nervous system catecholamine levels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00237350
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  • 5
    Electronic Resource
    Electronic Resource
    Phytotherapeutika bei Mastodynie, prämenstruellen Beschwerden und Zyklusstörungen (2000)
    Springer
    Der Gynäkologe 33 (2000), S. 36-39 
    Details
    ISSN: 1433-0393
    Keywords: Schlüsselwörter Keuschlamm ; Dopamin ; Prolaktin ; Mastodynie ; Key words Vitex Agnus castus ; Dopamine ; Proclactin ; Mastodynia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Aqueous ethanolic extracts of Vitex Agnus castus have well-characterised dopaminergic effects which block pituitary prolactin secretion. In women suffering from latent hyperprolactinaemia the exaggerated prolactin secretion in response to stress or deep sleep phases is significantly reduced under treatment with Agnus castus preparations. This appears to be why Agnus castus preparations are beneficial in the treatment of premenstrual mastodynia. The dopaminergic effects of Vitex Agnus castus may also be effective in the nigrostrial and in the mesolimbic dopaminergic systems and therefore also beneficial in the treatment of psychic and other vegetative premenstrual symptoms.
    Notes: Zusammenfassung Wässrig äthanolische Extrakte aus Vitex agnus-castus, der Frucht des Mönchspfeffers, enthalten wohlcharakterisierte dopaminerge Wirkprinzipien, die an der Hypophyse die Prolaktinsekretion blockieren. Dadurch wird bei Frauen mit latenter Hyperprolaktinämie die stress- und tiefschlafphaseninduzierte überschießende Prolaktinsekretion gebremst, so dass ein günstiger Einfluss auf die prämenstruelle Mastodynie registriert wird. Möglicherweise bewirken die dopaminergen Wirkprinzipien in Vitex agnus-castus auch durch eine Wirkung am nigrostriatalen oder mesolimbischen dopaminergen Gebieten eine Verbesserung psychischer und anderer vegetativer prämenstrueller Symptome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001290050007
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  • 6
    Electronic Resource
    Electronic Resource
    Hypothalamic control of prolactin secretion (1977)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 297 (1977), S. S75 
    Details
    ISSN: 1432-1912
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00587786
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