ISSN:
1432-1106
Keywords:
Adult and newborn rats
;
Brain slices
;
Taurine transport
;
Electrical stimulation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Brain slices from adult and newborn rats were incubated with [35S]taurine in Krebs-Ringer bicarbonate medium at pH 7.4. In both age groups electrical stimulation increased the oxygen consumption of the slices. The influx of taurine only increased in slices from adult rats. The influx conformed to Michaelis-Menten kinetics. In slices from adult rat Vmax increased and apparent Km remained unchanged during electrical stimulation. Both Km and Vmax were greater in adult than in newborn rats. The efflux of taurine from slices depended on the intracellular concentration of taurine and was not measurably influenced by electrical stimulation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00234128
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