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  • 2000-2004  (5)
  • 1960-1964  (62)
  • 1840-1849  (5)
  • Chemistry  (70)
  • Dendritic cells  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 323 (1963), S. 57-64 
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: The degree of electric charging of metal surfaces due to retarding of neutral metallic and semiconducting particles having various velocities has been determined. The effects are supposed to result from the exo-emission of electrons the amount of which depends on the velocities, masses, and impact angles of the particles.From the strong differences between the reactivities of solid substances during and after mechanical working it is concluded that the observed exo-emission is caused by exitation states at submicroscopic surface points.
    Notes: Die elektrische Aufladung von Metalloberflächen bei der Impuls-Bremsung nicht geladener, fliegender, metallischer und halbleitender Partikel verschiedener Geschwindigkeiten wird gemessen. Die beobachteten Erscheinungen lassen sich aus der Exo-Emission von Elektronen herleiten. Diese ergibt sich u. a. aus dem Zusammenhange zwischen der Elektronen-Austrittsarbeit der beteiligten Partner und der Größe der gebremsten Impulse. Die Ladungs-Übergänge hängen Übersichtlich vom Quadrat der Geschwindigkeiten, von der Masse und vom Auftreffwinkel der Körner ab. Einflüsse mechanischer Vorbehandlung der Festkörper, entsprechend früheren Beobachtungen, werden bestätigt.Im Zusammenhange mit den beobachteten großen Unterschieden des Reaktionsvermögens von Festkörpern während der Bearbeitung und nach ihrem Abschluß lassen die beobachteten Exo-Emissionen auf das Auftreten erhöhter Anregungszustände an submikroskopischen Orten während der Impuls-Bremsung schließen.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2277
    Keywords: Key words Rat liver transplantation ; Intrahepatic leukocytes ; Dendritic cells ; T lymphocytes ; Chimerism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Long-term graft acceptance and tolerance induction after allogeneic rat liver transplantation are well described. However, the underlying mechanisms remain unclear. In this study we investigated the cellular events within the liver graft during initial immunosuppression and long-term acceptance. Orthotopic liver transplantation was performed in the Dark Agouti (DA)-to-Lewis (LEW) and LEW-to-DA rat strain combination. In order to achieve long-term acceptance, LEW recipients of DA livers were treated with two different short-term therapies. Non-parenchymal cells (NPC) were isolated from liver allografts on days + 10 and + 100 after transplantation and donor-specific leukocytes were immunophenotyped by flow cytometry. Both the monotherapy and triple therapy prolonged graft survival (〉 100 days). Liver allografts from LEW donors into DA recipients were spontaneously accepted across a complete MHC mismatch without immunosuppression. Liver allograft rejection was induced by infiltrating alloreactive immunocompetent cells. But the intensities of cell infiltration in the early and late phases after transplantation did not correlate with eventual outcome. Donor-specific NPC decreased to 18–25 % on day + 10 in both therapeutic groups, but had rebounded to up to 40 % by day + 100. Recurrence of donor-specific cells was caused almost exclusively by rising T cell counts. The persistence of dendritic cells in the late phase after transplantation could be clearly demonstrated. Repopulation by donor-specific T lymphocytes was observed in long-term accepted liver grafts. This recurrence may be based on the differentiation of liver-derived progenitor cells. The persistent coexistence of donor and recipient cells within the liver allograft (intrahepatic chimerism) appears to be characteristic and may be important for long-term acceptance.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2277
    Keywords: Key words Liver/small bowel transplantation ; Tolerance ; Dendritic cells ; Kupffer cells ; Antigen-presenting cells ; Chimerism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The predictive value of chimerism was evaluated in three different transplantation models in the rat without immunosuppression: small bowel- (SBTx), liver- (LTx), and liver/small bowel transplantation (LSBTx) were performed in the Brown Norway (BN)-to-Lewis- (LEW) strain combination. Immunohistochemistry and flow cytometry were used to identify donor cells in the recipient's spleen. Their number did not change significantly during transient rejection or tolerance after LTx and LSBTx. However, the amount of donor-derived nonparenchymal cells within the liver allograft including antigen-presenting cells (APCs), such as dendritic and Kupffer cells, clearly mirrored the recipient's immune status: as expected, their number decreased during rejection, but recovered considerably during and after tolerance induction. We conclude that donor cells in the periphery of the recipient correlate with the presence of the allograft, but do not seem to influence graft acceptance actively. However, the kinetics of the detected donor APC population in the liver suggests their important role in modifying the recipient's immune response towards tolerance.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: D-Glucose, D-Galaktose, D-Mannose und 4.6-Benzal-α-D-glucose reagierten mit 2-Mercapto-äthylamin unter Bildung von Thiazolidin-Derivaten. Der Konstitutionsbeweis wurde durch Desulfurierung der Acetate mit Raney-Nickel erbracht, die zu den entsprechenden Hexitderivaten führte. Der Glucosederivat III entstehende I-[N-äthyl-acetamino]-2.3.4.5.6-penta-O-acetyl-1-desoxy-D-sorbit (IV) wurde auf einem unabhängigen Wege aus 1-äthylamino-1-desoxy-D-glucose erhalten.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 94 (1961), S. 3293-3297 
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die Synthese der genannten Anomeren erfolgte durch Benzylidierung und Glykosidierung des N-Formyl-D-glucosamins und alkalische Hydrolyse der N-Formyl-Gruppe.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 94 (1961), S. 1676-1682 
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die katalytische Hydrierung der aromatisch kondensierten 1.4-Oxazinone-(2) (Azacumarine) führt zu ihren 3.4-Dihydroderivaten, den Morpholonen-(2), die auch als Lactone der entsprechenden N-[o-Hydroxyl-aryl]-α-aminosäuren beschrieben werden können. Hydrierung der 1.4-Benzoxazinone-(2) mit Lithiumaluminiumhydrid liefert unter Öffnung des Lactonringes N-substituierte 1.2-Aminoalkohole.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 95 (1962), S. 985-995 
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Racem. Tetralin-p-chinol wird über die Strychninsalze der sauren 3-Nitro-phthal-säureester in die optischen Antipoden zerlegt. Die Konfiguration und Konformation der Antipoden wird diskutiert und zur Konfiguration und Konformation der östra-p-chinole auf Grund des optische Verschiebungssatzes und der Rotationsdispersion in Beziehung gesetzt. Daraus ergibt sich die absolute Konfiguration der Antipoden des Tetralin-p-chinols.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 95 (1962), S. 1000-1002 
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Umsetzung von D-Glucose, D-Galaktose, D-Mannose und L-Arabinose mit 3-Mercapto-propylamin ergab Substituierte Tetrahydro-1.3-thiazine. Die konstitution der Verbindung aus D-Glucose wurde durch Raney-Nickel-Desulfurierung zu einem auf unabhängigem Wege erhaltenen D-Sorbit-Derivat bewiesen.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 96 (1963), S. 2017-2018 
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 96 (1963), S. 2019-2023 
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Durch Inversion des C-Atoms 4 in einem entsprechend substituierten Derivat (VI) der 2.6-Didesoxy-2.6-diamino-β-D-glucose unter Bildung eines Dihydro-oxazinrings gelang die Umwandlung in ein Derivat (X) der 2.6-Didesoxy-2.6-diamino-β-D- galaktose, die daraus in kristallisiertem Zustand gewonnen wurde.
    Type of Medium: Electronic Resource
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