Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Although site of surgery and previous occurrence of postoperative nausea and vomiting are often used to decide whether prophylactic anti-emetic drugs are indicated, the value of these predictors is unclear. We compared these two risk factors against a simplified four-factor risk score. We analysed data from 1566 adult inpatients who received balanced anaesthesia without prophylactic anti-emetics. Sensitivity, specificity, predictive value and area under the receiver operating characteristic curve were used to quantify predictive properties. Nausea and vomiting occurred in 600 (38.3%) patients within 24 h. Sensitivity and specificity were, respectively, 47% and 59% for surgical site; 47% and 70% for history of postoperative nausea and vomiting; and 58% and 70% for risk score with three or more factors. The area under the curve for surgical site was 0.53 (95% CI 0.50–0.56); that for patient's history was 0.58 (95% CI 0.56–0.61) while for risk score it was 0.68 (95% CI 0.66–0.71; P 〈 0.001). Prediction using surgical site or patient's history alone was poor while the simplified risk score provided clinically useful sensitivity and specificity.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Postoperative nausea and vomiting (PONV) are frequent and unpleasant symptoms. This prospective study aimed to assess the efficacy of a multimodal approach to prevent PONV, and patient satisfaction using the willingness-to-pay method. Two validated risk scores were applied to forecast the individual risk for PONV in 900 consecutive patients of whom 108 were identified as high-risk patients (predicted risk: 79–87%). High-risk patients received multimodal anti-emetic prophylaxis: total intravenous anaesthesia with propofol, high fractional inspired oxygen (80%), omission of nitrous oxide, dexamethasone 8 mg, haloperidol 10 µg.kg−1, and tropisetron 2 mg. Of the remaining patients with low or moderate risk for PONV, a random sample of 71 females received balanced propofol-desflurane anaesthesia without prophylactic anti-emetics. All patients were interviewed 2 and 24 h after surgery for occurrence of nausea and vomiting. Patient satisfaction was measured using the willingness-to-pay method. The incidence of PONV (95%-confidence interval) in the control-group was 41% (29–51%), slightly lower than predicted by the risk scores (53–57%). The multimodal anti-emetic approach reduced the predicted risk (79–87%) in the high risk-group to 7% (3–14%). This was associated with a high willingness-to-pay median (25th/75th percentile) of £84 (£33–184) in the multimodal anti-emetic grouped compared to £14 (£4–30) in the control group. A multimodal anti-emetic approach can considerably reduce the incidence of PONV in high-risk patients and is associated with a high patient satisfaction as measured by the willingness-to-pay method.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 1433-0423
    Keywords: Schlüsselwörter Thrombendarteriektomie ; TEA ; Okulärer Blutfluss ; A. carotis ; Pulsamplitude ; Key words Thrombendarterectomy ; CEA ; Ocular blood flow ; Carotid artery ; Pulse amplitude
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Successful operations of clinically significant carotid artery stenosis by carotid endarterectomy (CEA) are leading to a better perfusion in the region of this artery. It still creates problems to make a statement about cerebral and ocular perfusion during the operation. Methods. In 10 patients who underwent a CEA the pulse amplitude (PA) of the intraocular pressure (IOP) was measured intraoperatively by a pneumotonograph (OBF-Systems, U.K.) and the so called pulsatile ocular blood flow (pOBF) was determined. The middle arterial blood pressure (MAP) was taken invasively during the operation. Results. During the clamping phases no PA could be recorded. PA (p=0.04) and pOBF (p=0.028) increased on the side which had been operated on. No correalations of PA and pOBF to MAP were found. Conclusion. This method can prove an increased pulsatile ocular blood flow after successful CEA.
    Notes: Zusammenfassung Erfolgreiche Thrombendarteriektomien (TEA) der A. carotis interna führen zu einer verbesserten Perfusion im Stromgebiet dieser Arterie. Es ist jedoch schwierig, während der Operation Aussagen über die zerebrale und okuläre Durchblutung zu treffen. Methode. Bei 10 Patienten mit klinisch signifikanter A.-carotis-Stenose, die sich einer A.-carotis-TEA unterzogen erfolgte eine nichtinvasive intraoperative Messung der Pulsamplitude (PA) des intraokularen Drucks mit einem Pneumotonographen (OBF-Systems, U.K.). Aus der PA wurde der sog. Pulsatile okuläre Blutfluss (pOBF) errechnet. Der mittlere arterielle Blutdruck wurde während der gesamten Operation invasiv gemessen. Ergebnisse. Während der Abklemmphasen konnte keine PA gemessen werden. Postoperativ kam es zu einem Anstieg der PA (p=0,04) und des pOBF (p=0,028) auf der operierten Seite im Vergleich zu den präoperativen Werten. Es wurde kein Zusammenhang zwischen dem pOBF bzw. der PA und dem mittleren arteriellen Blutdruck festgestellt. Schlussfolgerung. Diese Methode kann eine veränderte pulsatile okuläre Perfusion nach einer erfolgreichen TEA nachweisen.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...