ISSN:
1439-7609
Keywords:
Key words Proto-oncogene c-fos
;
Interfacial membrane
;
Osteolysis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Expression of the proto-oncogene c-fos was investigated by in situ hybridization and a study of the immunohistochemistry of the interfacial membranes surrounding the femoral component of failed cementless total hip arthroplasty (THA). The values of the proto-oncogene c-fos gene and protein were high in these interfacial membranes. High expression of the c-fos gene and protein was observed in the macrophage-like cells and fibroblast-like cells. However, there was little expression in multinucleated giant cells. We demonstrated the significance of the proto-oncogene c-fos in interfacial membranes – the first report of c-fos in total joint replacement failure.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s101650070007
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