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  • 1
    Electronic Resource
    Electronic Resource
    Startle potentiation in aversive anticipation: Evidence for state but not trait effects (2002)
    Oxford, UK : Blackwell Publishing
    Psychophysiology 39 (2002), S. 0 
    Details
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: The present study was undertaken to determine whether aversiveness contributes to startle potentiation in anticipation of affective pictures above and beyond the effects of emotional arousal. Further, participants high in trait anxious apprehension, which is characterized by worry about the future, were expected to show especially pronounced anticipatory startle responses. Startle blink reflex was measured during warning stimuli that predicted the valence of ensuing aversive/unpleasant, pleasant, or neutral pictures. Startle magnitude was larger in anticipation of aversive than of pleasant pictures and smallest in anticipation of neutral pictures. Enhanced startle potentiation was not found in anxious apprehension subjects. These data suggest that the aversive nature of stimuli contribute to the potentiation of startle above and beyond the effects of emotional arousal, which may be a universal phenomenon not modulated by individual differences.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/1469-8986.3920254
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  • 2
    Electronic Resource
    Electronic Resource
    New Functions for the Sialic Acid-Binding Adhesion Molecule CD22, a Member of the Growing Family of Siglecs (2001)
    Oxford, UK : Blackwell Science Ltd
    Scandinavian journal of immunology 53 (2001), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3083.2001.00868.x
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  • 3
    Electronic Resource
    Electronic Resource
    Activation of frontoparietal cortices during memorized triple-step sequences of saccadic eye movements: an fMRI study (2001)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 13 (2001), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: To determine the cortical areas controlling memory-guided sequences of saccadic eye movements, we performed functional magnetic resonance imaging (fMRI) in six healthy adults. Subjects had to perform a memorized sequence of three saccades in darkness, after a triple-step stimulus of successively flashed laser targets. To assess the differential contribution of saccadic subfunctions, we applied several control conditions, such as central fixation with or without triple-step visual stimulation, self-paced saccades in darkness, visually guided saccades and single memory-guided saccades. Triple-step saccades strongly activated the regions of the frontal eye fields, the adjacent ventral premotor cortex, the supplementary eye fields, the anterior cingulate cortex and several posterior parietal foci in the superior parietal lobule, the precuneus, and the middle and posterior portion of the intraparietal sulcus, the probable location of the human parietal eye field. Comparison with the control conditions showed that the right intraparietal sulcus and parts of the frontal and supplementary eye fields are more involved in the execution of triple-step saccades than in the other saccade tasks. In accordance with evidence from clinical lesion studies, we propose that the supplementary eye field essentially controls the triggering of memorized saccadic sequences, whereas activation near the middle portion of the right intraparietal sulcus appears to reflect the necessary spatial computations, including the use of extraretinal information (efference copy) about a saccadic eye displacement for updating the spatial representation of the second or third target of the triple-step sequence.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.0953-816x.2001.01472.x
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  • 4
    Electronic Resource
    Electronic Resource
    The 5′-proximal hairpin loop of lbi RNA is a key structural element in repression of d-galactan II biosynthesis in Klebsiella pneumoniae serotype O1 (2000)
    Oxford, UK : Blackwell Science Ltd
    Molecular microbiology 36 (2000), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The lbi (lipopolysaccharide biosynthesis interfering) RNA of phage Acm1, an untranslated RNA transcript of 97 nucleotides, previously shown to affect O-polysaccharide biosynthesis in various Escherichia coli strains, was found to downregulate the synthesis of the d-galactan II component of the O-specific polysaccharide in Klebsiella pneumoniae serotype O1. Enzymatic and Pb2+ probing experiments revealed that lbi RNA consists of two consecutive stem–loop structures, the 5′-proximal hairpin loop of 15 nucleotides being particularly accessible to single strand-specific probes. Based on the assumption that the 5′-proximal hairpin loop may be involved in an antisense interaction with cellular target RNAs, we randomly mutagenized one or two of its central nucleotides. Expression of mutated lbi RNA variants in K. pneumoniae serotype O1 relieved at least partly the repression of d-galactan II formation. In addition, a truncated version of lbi RNA lacking the 3′-proximal hairpin loop was almost as efficient as the wild-type RNA in downregulating d-galactan II synthesis. The results obtained indicate that the 5′-proximal hairpin loop of lbi RNA functions as a key structural element in the mechanism leading to the inhibition of d-galactan II biosynthesis in K. pneumoniae serotype O1.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2958.2000.01894.x
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  • 5
    Electronic Resource
    Electronic Resource
    Amalgam fillings and cognitive abilities in a representative sample of the elderly population (2000)
    Oxford, UK : Blackwell Publishing Ltd
    Gerodontology 17 (2000), S. 0 
    Details
    ISSN: 1741-2358
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objectives: The ongoing controversial discussion about a possible negative effect of amalgam fillings on the cognitive abilities and the pathogenesis dementia was the objective of the present study.Sample: A total of 300 patients aged from 70 to 103 years were selected from the multidisciplinary ‘Berlin Aging Study’ (Base). The sample was heterogeneous concerning lifestyle, education and social prestige. According to their dental state subjects were allocated into three groups: edentate ≥20 years (I) and residual teeth without (II) or with (III) amalgam restorations. All groups were matched for age and gender.Design: Dental examinations and various psychiatric as well as psychological assessments were carried out by professionals within the protocol of the BASE. Tests were chosen to reveal the presence and degree of dementia and assess cognitive abilities such as ‘perceptual speed’, ‘reasoning’, ‘memory’, ‘fluency’ and ‘knowledge’.Results: The present findings negate a correlation between the dental state and the pathogenesis of dementia and the physiological age-related decline in cognitive abilities. Thus the presence of amalgam fillings did neither correlate to a demented mental condition nor an impaired cognitive performance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1741-2358.2000.00039.x
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  • 6
    Electronic Resource
    Electronic Resource
    Obituary to Markus Koller Past-President of the European College of Gerodontology (2004)
    Oxford, UK : Blackwell Publishing Ltd
    Gerodontology 21 (2004), S. 0 
    Details
    ISSN: 1741-2358
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1741-2358.2004.00043.x
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  • 7
    Electronic Resource
    Electronic Resource
    Undergraduate teaching in gerodontology in Austria, Switzerland and Germany (2004)
    Oxford, UK : Blackwell Publishing Ltd
    Gerodontology 21 (2004), S. 0 
    Details
    ISSN: 1741-2358
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective:  To survey the present state of undergraduate teaching in the domain of gerodontology in Germany, Switzerland and Austria.Study participants:  All universities of Austria (A), Germany (D) and Switzerland (CH).Protocol:  A questionnaire on undergraduate teaching in gerodontology was mailed to all Deans (A: n = 3; CH: n = 4; D: n = 31) and all independent departments except paediatric dentistry and orthodontics (A: n = 11; CH: n = 15; D: n = 111).Results:  The questionnaires were completed and returned by 29 Deans (A: n = 2; CH: n = 4; D: n = 23) and 102 departments (A: n = 7; CH: n = 8; D: n = 87). In Austria, gerodontology is a very small component of the dental curriculum and the Deans did not want this to be increased. Most German universities claimed to teach some aspects of gerodontology to undergraduate students and 87.4% of the Deans voted for separate lectures in gerodontology. In Switzerland, gerodontology seems well established. The results of questionnaires from the independent departments revealed that in all three countries lectures were more prevalent (A: n = 0; CH: n = 4; D: n = 6) than practical training in nursing homes (A: n = 0; CH: n = 3; D: n = 6).Conclusion:  Considering the demographical shift which is leading to an increasing proportion of elderly in the population, the weighting of gerodontology in the undergraduate dental curriculum should be considered for revision in Austria and Germany.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1741-2358.2004.00031.x
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  • 8
    Electronic Resource
    Electronic Resource
    The uptake of dental services by elderly Germans (2001)
    Oxford, UK : Blackwell Publishing Ltd
    Gerodontology 18 (2001), S. 0 
    Details
    ISSN: 1741-2358
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective: The aim of the study was to assess the uptake of dental services by the old and very old population within the scope of the Berlin Aging Study (Berliner Altersstudie BASE).Design: A multi-disciplinary structured interview was performed on 928 subjects, aged from 70 to 103 years of whom 516 persons volunteered to take part in a 14-session intensive protocol. Six representative study groups were matched for age and gender. Subjects were asked to recall the timing of their most recent dental visit. Data were validated by sending for dental records and compared with all study participants from the multi-disciplinary intake assessment. Data were related to age group, dental state, dementia and education.Results: Reported last contact with dental services ranged from 2 weeks to 52 years (median 18 months) with a higher time lapse in the study groups aged 85 and older. Dentate subjects had seen their dentist more recently than edentate subjects. Higher education correlated with an increased dental utilisation. Subjective memory on the time lapse since the last dental appointment coincided in 13% of the subjects with available dental records (n=84), was misjudged between one and six months in 55%, and by more than six months in the remainder. Moderately or severely demented subjects who remembered their last dental appointment (n=48 of 70) showed no consistently different utilisation to healthy or mildly demented studs participants.Conclusion: Edentate old and very old subjects show the least frequent utilisation of dental services. Data on motivation and barriers to care are needed to develop strategies to improve the use of dental services and thus promote oral health in late life.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1741-2358.2001.00114.x
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  • 9
    Electronic Resource
    Electronic Resource
    Comparison of Residual Stress Depth Profiles in Welded Joints (2002)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 404-407 (Aug. 2002), p. 381-386 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/06/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.404-407.381.pdf
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  • 10
    Electronic Resource
    Electronic Resource
    Stable Parameter Range for 3C-SiC Sublimation Growth on Graphite (2004)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 457-460 (June 2004), p. 143-146 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/08/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.457-460.143.pdf
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