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  • 1
    ISSN: 1432-2161
    Schlagwort(e): Key words Osteonecrosis of the femoral head (ONFH) ; Magnetic resonance imaging (MRI) ; Gd-DTPA ; Fat suppression ; Radiological stage ; Bone marrow edema
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  Objective. To investigate the MR findings of necrotic lesions and the extralesional area of osteonecrosis of the femoral head (ONFH) for each of the radiological stages. Design and patients. Forty-nine hips in 29 patients (15 female, 14 male; mean age 38 years, range 17–59 years) were imaged using a 1.0-T superconducting magnet. T2-weighted spin echo pulse sequences (T2WI), spoiled gradient recalled echo pulse sequences (SPGR) and fat suppression SPGR (FS-SPGR), followed by Gd-DTPA enhanced fat suppression SPGR (Gd-FS-SPGR), were all obtained with the aid of a TORSO surface coil. Results and conclusions. While a normal fat intensity area with a low-intensity band on SPGR (band pattern) was seen in 16 of 16 stage 1 (100%), nine of 11 stage 2 (82%), four of 17 stage 3 (24%), and none of five stage 4 hips, all hips showed peripheral rim enhancement on Gd-FS-SPGR (100%). This enhancement band on Gd-FS-SPGR corresponded to histological findings of necrotic trabecular bone, repaired marrow, and fibrous reparative tissue. Bone marrow edema was also clearly demonstrated as a diffuse, high-intensity area outside this enhancement band on Gd-FS-SPGR in two stage 2 (18%), 12 stage 3 (71%), and one stage 4 hip (20%). In cases at stage 2 or more advanced stages with homogeneous or inhomogeneous low intensity on nonenhanced MRI, the reparative process both inside and outside the necrotic lesion, including bone marrow edema, was detected clearly on contrast- enhanced MRI.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    International orthopaedics 24 (2000), S. 92-96 
    ISSN: 1432-5195
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Résumé  Nous avons examiné la production de métalloprotéinases (MMP) par des fibroblastes dans 78 patients souffrant d’une ostéo-arthrite de la hanche. La production de MMP fut classée en 3 sous-sembles: 53 patients dans lequel seulement des MMP-2 furent détectées; 15 patients dans lequels des MMP-1, -2 et –3 étaient présentes; et 10 patients où des MMP-1, -2, -3 et aussi des MMP-9 furent détectées. Des différences importantes furent découvertes pour des paramètres cliniques et radiologiques parmi les sous-sembles. Il y’a une correlation positive entre la production de MMP-9 et une destruction rapide de la hanche.
    Notizen: Abstract  In 78 patients undergoing a total hip replacement we examined the production of matrix metalloproteinases (MMP) by the fibroblasts from the connective tissue of the acetabulum; we then correlated these findings with clinical and radiological characteristics of the same patients. In 53 patients only MMP-2 was produced; in 15 cases MMP-1, -2 and -3 were present; and in 10 cases not only MMP-1, -2, -3 but also MMP-9. Significant differences among the clinical and radiological parameters were found in the 3 subsets. A positive correlation between the production of MMP-9 and a rapid destruction of the hip joint was found.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    ISSN: 1435-604X
    Schlagwort(e): Keywords: Bactericidal effect; Crystal violet; Dental plaque; Photodynamic action; Photosensitiser; Yellow He-Ne laser
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin , Physik , Technik allgemein
    Notizen: Abstract . The purpose of this study was to evaluate the effect of yellow He-Ne laser irradiation in the presence of crystal violet (CV) solution on dental plaque formation in the human mouth. Four enamel specimens were fixed on a retainer, one of which was placed on both maxillary buccal sites of four subjects. The retainers were assigned randomly to 3- or 7-day experimental periods and the right or left buccal sites for the evaluation of plaque formation on the specimens. Then, the specimens were assigned randomly to four treatments as follows: A, laser irradiation; B, CV application; C, CV application and laser irradiation and D, no treatment (control). At three and seven days after the treatments, the inhibitory effects of plaque formation on the specimens were evaluated by measuring the thickness of the plaque on each section. Analysis of the plaque formation scores revealed that treatment C had a significantly greater inhibitory effect on plaque formation than treatment A, B and D after 3 days, however there were no significant differences among the plaque formation scores of the four treatment groups after 7 days. Analysis of the plaque thickness revealed that at both 3 and 7 days after treatment, the plaque layers after treatment C were significantly thinner than those after treatments A, B and D. These results indicated that yellow He-Ne laser irradiation in the presence of CV had an inhibitory effect of plaque formation in human mouth.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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