ISSN:
1573-1111
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract By using methyl orange as a competitive complexant, it was shown that solutions of poly(ethylene glycol), poly(propylene glycol) and poly(N-vinylpyrrolidone) equivalent to a concentration of 1.67 mM monomer are able to form soluble inclusion complexes with 0.20 mM solutions of α-, β- and γ-cyclodextrins. The complex formation is independent of polymer chain length. Poly(ethylene glycol) solutions complexed, on average with 40%, 45% and 75% of α-, β-, and γ-cyclodextrin, respectively. A poly(propylene glycol) solution complexed 55% α-cyclodextrin, 80% β-cyclodextrin and 90% γ-cyclodextrin. Poly(N-vinylpyrrolidone) solutions complexed on average with 90% of α-, β-, and γ-cyclodextrin.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01041543
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