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  • 1
    Electronic Resource
    Electronic Resource
    Experimental Results with a New Gold-Coated Multicellular Stent Design: Comparison with a Conventional Slotted Tube Stent in the Coronary Overstretch Model of the Pig (1999)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of interventional cardiology 12 (1999), S. 0 
    Details
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: Despite major progress in coronary stenting over the past decade, the problem of restenosis remains of concern. Recent developments to reduce the incidence of restenosis have focused on modifications in stent design. The aim of the present study was to examine the implant characteristics and vascular response of a new balloon-expandable gold-coated stent (16 longitudinal struts per cross section) with 8 cell multicellular geometry in comparison to a conventional gold-coated slotted tube stent (12 struts per cross section). Methods and Results: A total of 26 stents of new and conventional designs were implanted in 13 pigs using the coronary overstretch model. There were no differences in baseline angiographic and implant parameters. For the mean implant diameters of 2.39 ± 0.23 mm (multicellular design) and 2.40 ± 0.36 mm (conventional design), the metal surface of the stent accounted for a total vessel area of 25%± 1.9% and 30.7%± 1.5%, respectively (P 〈 0.05). Histologic follow-up at 28 days demonstrated a 35.5% reduction in the mean vascular injury score (0.69 ± 0.79) for the multicellular versus the conventional design (1.07 ± 0.49, P = 0.04) despite comparable vascular overstretch. This was accompanied by a significant reduction in the mean neointimal area (0.7 ± 0.6 vs 1.6 ±0.7 mm2, P 〈 0.01) and percent diameter stenosis (13.9 ± 14.7 vs 29.6 ± 17.0, P 〈0.05). Histologic data at 3 months revealed similar results with respect to mean vascular injury, neointimal thickness, and percent diameter stenosis. Conclusions: The more homogenous force distribution with the multicellular stent design results in less vessel injury and reduced restenosis compared to the conventional slotted tube design. Between 1 and 3 months there was no further increase in neointimal formation indicating that the multicellular design does not induce ongoing arterial injury that could promote late neointimal formation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-8183.1999.tb00231.x
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  • 2
    Electronic Resource
    Electronic Resource
    HYDROLOGY OF A DRAINED FORESTED POCOSIN WATERSHED (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the American Water Resources Association 33 (1997), S. 0 
    Details
    ISSN: 1752-1688
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Notes: : In order to assess the effects. of silvicultural and drainage practices on water quality it is necessary to understand their impacts on hydrology. The hydrology of a 340 ha artificially drained forested watershed in eastern North Carolina was studied for a five-year period (1988–92). Effects of soils, beds and changes in vegetation on water table depth, evapotranspiration (ET) and drainage outflows were analyzed. Total annual outflows from the watershed varied from 29 percent of the rainfall during the driest year (1990) when mostly mature trees were present to as much as 53 percent during a year of normal rainfall (1992) after about a third of the trees were harvested. Annual ET from the watershed, calculated as the difference between annual rainfall and outflow, varied from 76 percent of the calculated potential ET for a dry year to as much as 99 percent for a wet year. Average estimated ET was 58 percent of rainfall for the five-year period. Flow rates per unit area were consistently higher from a smaller harvested block (Block B - 82 ha) of the watershed than from the watershed as a whole. This is likely due to time lags, as drainage water flows through the ditch-canal network in the watershed, and to timber harvesting of the smaller gaged block.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1752-1688.1997.tb03530.x
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  • 3
    Electronic Resource
    Electronic Resource
    Genetic Diversity for RFLPs in European Maize Inbreds (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Plant breeding 111 (1993), S. 0 
    Details
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Restriction fragment length polymorphisms (RFLPs) have been proposed for predicting the yield potential of different types of cross. Their has been evaluated in 15 flint and 12 dent inbreds from the European maize (Zea mays L.) germplasm as well as in 68 F1 crosses (21 flint × flint, 14 dent × dent, and 33 flint × dent) produced between them. The materials were evaluated for F1 performance and midparent heterosis of grain yield, dry matter content (DMC) and plant height in two environments in Germany. Genetic distances (GDs) between parental lines, calculated from RFLP data of 194 clone-enzyme combinations, showed greater means for flint × dent (0.67) than dent × dent (0.62) and flint × flint (0.55) crosses. Cluster analysis based on GDs resulted in a clear separation of flint and dent lines and agreed well with pedigree information. For the complete set of 64 crosses analyzed (excluding 4 crosses between closely related lines) correlations of GD with F1 performance and heterosis were significant for all traits except F1 performance of DMC. When separate calculations were performed for individual subjets of crosses, correlations of GD with Fl performance and heterosis were significantly positive (0.48 ≤ r ≤ 0.80) for all traits in the flint × flint crosses, but not significant for the subsets of flint × dent and dent × dent crosses. Our results confirm those of previous investigations in that the predictive value of RFLP data is restricted to crosses between lines from the same heterotic group, and cannot be applied to crosses between lines from genetically divergent heterotic groups.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0523.1993.tb00632.x
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  • 4
    Electronic Resource
    Electronic Resource
    A DNA Probe for Rapid Screening of Sugar Beet (Beta vulgaris L.) Carrying Extra Chromosomes from Wild Beets of the Procumbentes Section (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Plant breeding 107 (1991), S. 0 
    Details
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Genes from wild species of the Procumbentes section can be transferred to sugar beet chromosomes via translocations. Since large translocations, including for example a gene for nematode resistance, generally result in meiotic disturbances, there is a need to select new diploid resistant beets from progenies of monosomic wild beet addition lines. A dispersed repetitive DNA probe, which is closely correlated with the resistance gene and hybridizes exclusively with wild beet DNA, appears to be highly superior to selection based on isozyme markers. Characteristic ‘fingerprints’ on the available monosomic addition lines reveal the existence of at last 5 different chromosomes in the wild species each housing a gene for nematode resistance. This probe can be used advantageously to identify individuals carrying the intact or fragmented wild beet chromosomes, or even various amounts of translocated chromatin. Strategies are discussed for the identification of new translocation types using straightforward squash dot or Southern hybridization techniques in combination with the wild beet DNA probe.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0523.1991.tb00550.x
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  • 5
    Electronic Resource
    Electronic Resource
    Development of RFLP Markers for Barley (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Plant breeding 107 (1991), S. 0 
    Details
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: A PstI-based genomic library from barley DNA was screened for RFLPs in the three relatively-distant cultivars ‘Alexis’ (2-row spring type), ‘Igri’ (2-row winter type) and ‘Mammut’ (6-row winter type), digested with BamHI, EcoRI and HindIII. 50 % of the 108 DNA fragments studied represented single-copy sequences, 29 % low-copy and 21 % repetitive sequences. The DNA probes were assigned to discrete barley chromosomes with the aid of wheat/barley addition lines. 80 % of the single- and low-copy sequences hybridized with both barley and wheat DNA, whereas most repetitive sequences gave signals only with barley DNA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0523.1991.tb00530.x
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  • 6
    Electronic Resource
    Electronic Resource
    X-Linked Dilated Cardiomyopathy (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 752 (1995), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1995.tb17457.x
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  • 7
    Electronic Resource
    Electronic Resource
    New measurements of appearance potentials and optical absorption of Na2F and Na3O (1997)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 106 (1997), S. 3865-3869 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Oxides and fluorides of sodium clusters were produced by reacting a beam of metal clusters with N2O or SF6 in the region between nozzle and skimmer. The threshold for single photon ionization was measured by using a pulsed, frequency doubled visible dye laser or a UV dye laser and detecting ions with a quadrupole mass spectrometer. Resonant two-photon ionization was employed to record optical spectra. Comparisons with previous measurements and theoretical predictions are discussed. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.473107
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  • 8
    Electronic Resource
    Electronic Resource
    An Extended Linkage Map of Sugar Beet (Beta vulgaris L.) Including Nine Putative Lethal Genes and the Restorer Gene X (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Plant breeding 111 (1993), S. 0 
    Details
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: An extended genetic map of sugar beet (Beta vulgaris L.) is presented encompassing 177 segregating markers (2 morphological traits, 7 isozymes, and 168 RFLP markers) on 9 linkage groups. The linkage map comprises 1057.3 cM equivalent to an average genetic spacing of 6.0 cM/marker. The length of individual linkage groups varies between 80.7 (group VIII) and 167.4 cM (group VIII). The number of markers per linkage group ranges between 13 and 24. No indication of duplicate regions was found, confirming the true diploid nature of B. vulgaris. Twenty-six markers (15 %) deviated significantly (a = 0.01) from the expected segregation ratio. This distorted segregation was probably caused by linkage with lethal genes. Four such genes (designated Let Ib, Let 5b, Let 6b, Let 8) could be located at discrete positions due to their absolute linkage to skewed RFLP markers. The restorer gene X has been located terminally on linkage group ÜI, 9.6 cM distant from RFLP marker pKP1238.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0523.1993.tb00641.x
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  • 9
    Electronic Resource
    Electronic Resource
    Identification of gene products of the P1 operon of Mycoplasma pneumoniae (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 5 (1991), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Gene P1 of Mycoplasma pneumoniae, which codes for a major adhesin, is flanked by two sequences with open reading frames designated QRF4 and QRF6 (Inamine et al., 1988b). In order to identify proteins translated from these ORFs, gene fusions between the N-terminus of the RNA replicase of the Escherichia coli bacteriophage MS2 and selected regions of ORF4 and ORF6 were constructed. The corresponding fusion proteins synthesized in Escherichia coli were used to immunize mice. Antisera directed against ORF4-related sequences did not recognize M. pneumoniae antigens in Western blot analysis, but antisera directed against ORF-6-derived fusion proteins reacted with two M. pneumoniae proteins of 40kDa and 90kDa. In addition, some of the antisera also recognized proteins that formed in a sodium dodecyl sulphate/polyacrylamide gel a protein ladder between 115 and 145 kDa.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1991.tb02110.x
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  • 10
    Electronic Resource
    Electronic Resource
    Initial Experience with a New Balloon-Guided Single Lead Catheter for Internal Cardioversion of Atrial Fibrillation and Dual Chamber Pacing (1999)
    Oxford, UK : Blackwell Publishing Ltd
    Pacing and clinical electrophysiology 22 (1999), S. 0 
    Details
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: Based on the observation that internal cardioversion (IntCV) of atrial fibrillation is effective with electrodes in the right atrium and pulmonary artery, a new balloon-guided catheter and external defibrillation device with optional dual chamber pacing was evaluated. Methods: IntCV was attempted in 27 patients (age: 57 ± 10 years, duration: 14 ± 18 months, left atrial diameter 56 ± 8 mm) using a new defibrillation device (Alert, EP MedSystems, Inc., NJ, USA) that allows the delivery of biphasic shocks (0.5–15 J, variable tilt), atrial and ventricular pacing, and online signal recording. Pacing and defibrillation shocks were applied via a 7.5 Fr balloon-guided catheter (EP MedSystems, Inc.). Pacing, sensing, and triggering were established through the proximal atrial array and an electrode ring between both defibrillation arrays and a single ventricular electrode ring. Catheters were inserted from the antecubital vein. Results: In 25 of 27 patients sinus rhythm was restored with a mean energy of 6.7 ± 4.5 J. In five patients, atrial postshock pacing was required for bradycardia and atrial premature beats. The mean fluoroscopy time was 2.0 ± 1.3 minutes. Conclusion: The high success rate, ease of application, and backup dual chamber pacing suggest that this system is an alternative to established methods of cardioversion. In certain indications, such as failure of prior external cardioversion and situations in which a standard pulmonary balloon catheter is needed, this system would be advantageous.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-8159.1999.tb00338.x
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