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  • 1
    Electronic Resource
    Electronic Resource
    Antigen-induced tenosynovitis in hypersensitized rabbits: a model for rheumatoid tenosynovitis (1988)
    Springer
    Rheumatology international 8 (1988), S. 47-53 
    Details
    ISSN: 1437-160X
    Keywords: Rabbit ; Tenosynovitis ; Antigen ; Tendon ; Rheumatoid arthritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Rabbits were first immunized and later challenged with the same antigen (bovine serum albumin, or ferritin) by injection into the tibialis anterior tendon. Inflammatory changes of the tenosynovium and epitenon included infiltration by neutrophils (early) and mononuclear cells (later) over a 6-week course of tenosynovitis. A pattern of antigen entrapment in the tendon together with immunoglobulin was shown by use of radiolabelled antigen and immunochemical staining. Half-life of antigen in the tissues averaged 5 days over the 6-week period. Changes in the epitenon included cellular necrosis, appearance of phagocytic cells, and disruption of the collagen matrix. Tissues of control animals (challenged without prior immunization) showed minimal changes and significantly less retention of antigen (P〉0.005). The model is relevant to the mechanism of tendon damage associated with antigen-driven chronic inflammation, as may be the case in rheumatoid arthritis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00271834
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Changes in mean trabecular orientation in the medial condyle of the proximal tibia in osteoarthritis (1995)
    Springer
    Calcified tissue international 57 (1995), S. 69-73 
    Details
    ISSN: 1432-0827
    Keywords: Trabecular orientation ; Osteoarthritis ; Medial tibial condyle ; Subchondral sclerosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract In osteoarthritis of the knee, degenerative changes occur in the articular cartilage and underlying subchondral bone, particularly of the medial tibial condyle. Cancellous bone sclerosis that accompanies osteoarthritis is not only the result of an increase in bone volume fraction but also a change in trabecular structure. In a comparison with agematched controls (n=4), osteoarthritis (n=11) demonstrated a significant (P≤0.05) increase in bone volume fraction and trabecular thickness. Overal trabecular orientation in the osteoarthritic group was more vertical or perpendicular to the articular surface than the control group (P≤0.05) especially in the trabeculae of the cancellous bone layer closest to the articular surface. These alterations in trabecular bone structure could have significant consequences for the mechanical properties of osteoarthritic bone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00299000
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Ochronotic arthropathy: case report and review of the literature (1999)
    Springer
    International orthopaedics 23 (1999), S. 122-125 
    Details
    ISSN: 1432-5195
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé  L’ochronose est une manifestation musculo-squélettique de l’alkaptonurie dûe à un désordre métabolique qui accompagne diverses anomalies systemiques et associé au depôt de pigments acides homogénetiques dans les tissues congonctifs. Nous decrivons deux cas d’ arthopathie presentant des douleurs progressives et des symptômes de dégénerescence avancée de la region lombo-sacrée. Cet article inclut la bibliographie, les diagnostics differentiels et le traitement de cette maladie rare. La therapie classique est toujours d’ actualité, mais l’implantation de prothéses peut être offerte dans des cas d’ atteintes severes des articulations majeures.
    Notes: Abstract  Alkoptonuria is an inherited metabolic disorder which is associated with various systemic abnormalities and related to the deposition of homogentisic acid pigment in connective tissues. These pigmentary changes are termed ”ochronosis”. We describe two patients with ochronotic arthropathy who presented with progressive and advanced degenerative changes in the lumbo-sacral spine. The literature, differential diagnosis and management of this rare condition are reviewed in this article. Management is usually conservative, but replacement surgery may be offered for severely affected major joints.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002640050325
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  • 4
    Electronic Resource
    Electronic Resource
    Letters to the edior (1986)
    Hoboken, NJ [u.a.] : Wiley-Blackwell
    Journal of Orthopaedic Research 4 (1986), S. 129-131 
    Details
    ISSN: 0736-0266
    Keywords: Life and Medical Sciences
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jor.1100040117
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Descriptive anatomy of fibrocartilaginous menisci in the finger joints of the hand (1985)
    Hoboken, NJ [u.a.] : Wiley-Blackwell
    Journal of Orthopaedic Research 3 (1985), S. 484-491 
    Details
    ISSN: 0736-0266
    Keywords: Fibrocartilage ; Anatomy ; Digital joints ; Life and Medical Sciences
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Observations were made from the dissection of 156 digital joints (thumbs excluded). In all joints fibrocollagenous menisci projected into the articular cavity from a ring-like structure based on the joint capsule. These meniscal structures separated the articulating cartilage surfaces at the margins of the joint. Histological examination confirmed a fibrocartilaginous nature of the tissue which demonstrated positive staining for proteoglycans and collagen fibers. Although generally similar in form, these meniscal structures varied in extent when compared between joint groups. The greatest amount and articular contribution was noted in metacarpophalangeal joints with least being found distally.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jor.1100030411
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  • 6
    Electronic Resource
    Electronic Resource
    Standardized biomechanical measurement for varus-valgus stiffness and rotation in normal knees (1988)
    Hoboken, NJ [u.a.] : Wiley-Blackwell
    Journal of Orthopaedic Research 6 (1988), S. 863-870 
    Details
    ISSN: 0736-0266
    Keywords: Life and Medical Sciences
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Seventeen female and 24 male subjects had varus and valgus and apparent rotations measured using a standardized mechanical testing device that cyclically applied a 20-Nm moment in each direction. Five parameters-apparent varus rotation, apparent valgus rotation, apparent overall rotation, varus stiffness, and valgus stiffness showed intersubject variations approaching 40%. Right-left variations in the same subject averaged 12%, with no significant right-left differences overall. Female knees rotated 66% more than male knees and were 35% less stiff. The ratio of apparent valgus rotation to apparent varus rotation averaged 0.775, and the ratio of valgus stiffness to varus stiffness averaged 1.23 for all knees. Stiffness and rotation parameters were highly correlated for both genders in the valgus phase of testing. Results suggest that although magnitudes of measured parameters vary considerably from subject, common relationships between parameters from the same normal knee exist.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jor.1100060610
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    Paper (German National Licenses)
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