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  • 1
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Design details and initial results are presented for a low-temperature scanning tunneling microscope specifically intended for measurements of ballistic-carrier transmittance through heterostructures. The basic design is of the Besocke type, modified for ballistic electron emission microscopy and spectroscopy (BEEM). This instrument is the first to acquire BEEM spectra below 77 K. Salient features are (1) operation in a liquid-helium storage Dewar to below 6 K, (2) a lateral positioning range of 5 mm at low temperature, and (3) lateral drift rate less than 0.2 nm/h at the lowest temperatures. For BEEM spectroscopy, the microscope's high positional stability allows extended signal-averaging at a single location on the sample. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Teaching statistics 10 (1988), S. 0 
    ISSN: 1467-9639
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mathematics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Fatigue & fracture of engineering materials & structures 11 (1988), S. 0 
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract— A comparison was made at room temperature of the fatigue sequence in Monel K 500 (N05500), both between the different states of solution heat treated, aged, and overaged, and with nickel that had been studied previously. The test mode was reversed bending and monitoring was by Nomarski interference contrast microscopy, in conjunction with sequential microhardness measurements. It was found that variations in Monel between the heat treated states were minor in comparison to differences with nickel. In Monel, the fatigue resistance was relatively poor because of ready intergranular, as well as transgranular, cracking. To achieve a significant life, the stress level had to be kept well below the yield strength, low enough to delay the onset of visible slip, for cracking would follow promptly. This meant that, in contrast to nickel, stress levels high enough to invoke strain hardening and obvious secondary slip led to exceedingly short lives. Also, inclusions mattered, slip occurring preferentially in their vicinity.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Macmillan Magazines Ltd.
    Nature 392 (1998), S. 558-559 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Termite nests provide a controlled environment and physical defence for the colonies of insects they house. Another important factor involved in colony defence may be volatile chemicals present in the nest: we have found the hydrocarbon naphthalene in extracts of the nest material produced by ...
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1041
    Keywords: Key words Hypoxaemia ; Pharmacokinetics ; Pharmacodynamics; frusemide ; paracetamol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objective: The influence of hypoxaemia on the disposition of two common drugs has been examined in ten adults with stable chronic respiratory failure. Methods: There were two experimental periods in this cross-over study: during these periods supplemental oxygen was either withheld or administered to impose clinical hypoxaemia or maintain normoxaemia, respectively. Each participant received either oral (40 mg) or intravenous (20 mg) frusemide combined with oral paracetamol (500 mg) on consecutive days of the two experimental periods. Results: The total (bound plus unbound) plasma clearance of frusemide during hypoxaemia (arterial oxygen tension, PaO2 ≤ 50 Torr) was not significantly different from the value during normoxaemia (PaO2 ≥ 60 Torr) [76.9 and 62.4 ml ⋅ min−1]. The volume of distribution was not affected by acute hypoxaemia (121 ml ⋅ kg−1 without and 109 ml ⋅ kg−1 with oxygen; P 〉 0.05). Renal and non-renal clearances of frusemide were similar during the period of hypoxaemia (31 and 38 ml ⋅ min−1, respectively) compared to respective values during supplemental oxygen delivery (29 and 32 ml ⋅ min−1). The absolute bioavailability of frusemide during hypoxaemia (0.62) was not different to that obtained during normoxaemia (0.56). The combined sodium and potassium excretion rate (expressed as a function of the frusemide excretion rate) was not altered by changing the oxygen tension. The pharmacokinetics of paracetamol were unaffected by hypoxaemia.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1573-2932
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract The concentrations of methylmercury (MeHg) in 124 samples of muscle taken from nine species of common sharks of varying sizes and locations along the Florida coast were determined. Muscle MeHg levels averaged 0.88 μg/g (wet sample basis) and ranged from 0.06 to 2.87 μg/g, with 33.1% of the samples exceeding the U.S. Food and Drug Administration's 1 μg/g action level. Differences were found in MeHg concentration by species but not by sex. A positive correlation between MeHg levels and shark size was found such that most sharks larger than approximately 200 cm total length contained MeHg concentrations exceeding the 1 μg/g action level. Fetal sharks contained consistently lower MeHg levels than their mothers. Sharks collected off southern regions of the state contained significantly higher MeHg concentrations than those off the northeast coast. The human health concerns for consumers of Florida shark meat are discussed in relation to these findings.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1617-4623
    Keywords: Key wordsColletotrichum trifolii ; Growth polarity ; Ras ; Signal transduction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Ras is a low-molecular-weight guanine nucleotide (GDP/GTP)-binding protein that transduces signals for growth and differentiation in eukaryotes. In mammals, the importance of Ras in regulating growth is underscored by the observation that activating mutations in ras genes are found in many animal tumors. Colletotrichum trifolii is a filamentous fungal pathogen of alfalfa which causes anthracnose disease. To investigate signaling pathways that regulate growth and development in this fungus, a gene encoding a Ras homolog (CT-Ras) was cloned from C. trifolii. CT-Ras exhibited extensive amino acid similarity to Ras proteins from higher and lower eukaryotes. A single amino acid change resulting in mutationally activated CT-Ras induced cellular transformation of mouse (NIH 3T3) fibroblasts and tumor formation in nu/nu mice. In Colletotrichum, mutationally activated CT-Ras induced abnormal hyphal proliferation and defects in polarized growth, and significantly reduced differentiation in a nutrient-dependent manner. These results show that C. trifolii Ras is a functional growth regulator in both mammals and fungi, and demonstrate that proper regulation of Ras is required for normal fungal growth and development.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of atmospheric chemistry 8 (1989), S. 277-298 
    ISSN: 1573-0662
    Keywords: Acetone ; propane ; model ; measurement ; season ; source ; hydrocarbons ; PAN
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Geosciences
    Notes: Abstract We present 1-D eddy diffusion model calculations of the distributions of propane and acetone in the atmosphere for continental conditions. The magnitude of the surface seasonal variation in propane mixing ratios that we obtain is in general agreement with measurements at the surface and in the free troposphere. A comparison of the absolute values of the model with propane measurements suggests that a larger surface flux than we have used may be more appropriate for continental conditions. The acetone model results for summer conditions that we obtain are also in reasonable accord with measurements. However, we find serious disagreement between the model winter profiles of acetone and the measurements at the tropopause and in the lower stratosphere. The measured values are lower than the model values at 45° N by a factor of 7–30. In addition, it is also surprising that, given the relatively long lifetime of acetone, free tropospheric values of acetone more representative of surface values have not been measured. The results simulating the decay of elevated levels of propane in the upper troposphere caused by rapid convective transport of boundary layer air indicate that propane will be primarily dispersed by transport rather than destroyed photochemically. Thus, the impact on acetone and PAN is minimal.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Antonie van Leeuwenhoek 55 (1989), S. 99-107 
    ISSN: 1572-9699
    Keywords: vanadate ; S. cerevisiae ; respiration ; mitochondria
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Growth of Saccharomyces cerevisiae on non-fermentable medium was more sensitive to inhibition by vanadate than growth of fermentable medium. The frequency of petite mutants increased in cultures grown for 18 hours in fermentable medium containing vanadate. However, oxygen uptake markedly increased in yeast cultures grown in the presence of vanadate, a similar effect being produced by phosphate. It was also found that oligomycin toxicity was relieved by vanadate. These results suggest that vanadate may interact with the mitochondria of S. cerevisiae.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 27 (1987), S. 781-787 
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The relationships between equilibrium melting temperatures (Tm*) and crystalline morphology of poly[3,3bis(ethoxymethyl)oxetane], (polyBEMO), poly[3,3-bis (azidomethyl)oxetane], (polyBAMO), and poly(ethylene oxide), (PEO), were characterized. The Hoffman-Weeks extrapolation procedure led to Tm* values of 92, 102, and 69°C for these three polymers, respectively. The gross morphologies of polyBEMO, polyBAMO, and PEO were studied as a function of melt-liquid temperature (Ti) and isothermal crystallization temperature (Tc) by visible light microscopy. Spherulitic morphologies were observed for polyBEMO, polyBAMO, and PEO when Ti was above Tm*, while nonspherulitic (hedritic) morphologies were observed at Tls below Tm*. Mixed morphologies were observed when Tl was approximately equal to Tm*.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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