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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Intensive care medicine 21 (1995), S. 475-481 
    ISSN: 1432-1238
    Keywords: Tracheostomy ; Methods ; ICU ; Postoperative complications ; Follow-up studies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective Percutaneous dilatational tracheostomy is increasingly practiced in intensive care units and has a low incidence of early complications. The late effects of this procedure are still poorly known and were the focus of this study. Design Prospective descriptive clinical study. Setting Interdisciplinary intensive care unit in a 300-bed teaching hospital. Patients A consecutive group of critically ill patients who underwent percutaneous tracheostomy between Nov. 90 and March 93, surviving at least 2 months after decannulation. Measurements and results There were 17 patients fulfilling the inclusion criteria and 16 of them were seen and examined. The follow-up protocol required a formal standar dized patient interview, a physical examination of the stoma site and a fiberoptic laryngotracheoscopy. Results of these sub-tests and overall outcome rating were standardized and expressed as good, moderate or poor. Subjective rating was good in all patients. All denied suffering from any side effects of their tracheostomy. Clinical examination revealed neither stridor nor hoarseness in any of the patients. Most of the scars were whitish and less than 1 cm in length, a few were sunken in, none had adhesions. In 15 patients the clinical result was good and in one, moderate (whitish, sunken-in scar, longer than 2 cm). Ten patients underwent tracheoscopy, while 6 did not. There were no signs of significant stenosis or tracheomalacia. In 8 patients with minor findings results were scored as good, while 2 were classified as moderate (combination of swelling and scar formation of a string-like membrane). The overall rating was good in 13 patients (81%) and moderate in 3 patients (19%). There were no poor outcomes. Conclusions Late outcome of percutaneous dilatational tracheostomy in critically ill patients is mostly good. Pending further studies, the use of this technique in intensive care units appears justified.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1238
    Keywords: Nitric oxide ; Monitoring ; Chemiluminescence assay ; Electrochemical assay
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Monitoring of nitric oxide (NO) and nitrogen dioxide (NO2) is a prerequisite for the clinical use of NO. Chemiluminescence, the reference method, cannot be used as a routine in clinical practice in view of its cost and other restraints. This study was performed to evaluate a device using an electrochemical method (Polytrons NO and NO2, Dräger®). Forty-nine simultaneous measurements of NO and various oxides of nitrogen (NOx) concentrations by the two apparatus were performed. NO measurements by means of these two methods are very well correlated (r=0.96;p〈10–5). The mean difference according to the method of Bland and Altman was 2.8±1.7 ppm, with the limits of agreement at −0.6 and +6.2 ppm (confidence interval of 95%). There was also a good correlation between measurements of NO2 obtained via Polytrons and NOx via chemiluminescence (r=0.84;p〈10−5). However, NO2 measurements obtained via Polytron may be insufficient to exclude potential toxicity of NO2 due to the inability to detect measurements in the ppbrange. This study demonstrates that devices designed for industrial purposes (Polytrons NO and NO2, Dräger®) can be used for clinical purposes.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 210 (1975), S. 151-159 
    ISSN: 1432-1459
    Keywords: F wave latency ; Diabetes ; Neuropathy in diabetes ; Polyneuropathy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 44 Gesunden und 30 unselektionierten Diabetikern wurde die Latenz der F-Welle in Abhängigkeit von der Armlänge bei Reizung des N. medianus untersucht und mit den Ergebnissen der konventionellen Nervenleitgeschwindigkeitsmessung verglichen. Die Latenz der F-Welle des N. medianus ist nur unter Berücksichtigung der Armlänge, zu der sie positiv korreliert ist, diagnostisch relevant. Die Messung der F-Wellen-Latenz erbrachte im Vergleich zur konventionellen NLG-Bestimmung eine klarere Trennung von Normalbereich und pathologischem Bereich. Dies ist darauf zurückzuführen, daß sich diskrete Leitverzögerungen über eine ca. 5–6fach längere Wegstrecke, wie dies bei der anti- und orthodromen Impulsleitung über motorische Nervenfasern für die F-Welle der Fall ist, deutlicher aufsummieren. — Die aus der F-Wellen-Latenz ermittelten Nervenleitgeschwindigkeiten zeigen eine 3–4fach geringere Streuung als die konventionellen Nervenleitgeschwindigkeiten. Die Methode der F-Wellen-Latenzbestimmung, die nur einen Reizort benötigt, erscheint daher geeignet, beginnende Stadien einer Leitverzögerung motorischer Nervenanteile früher und eindeutiger zu erfassen als die konventionelle NLG-Bestimmung.
    Notes: Summary The N. medianus was stimulated electrically in 44 healthy persons and in 30 unselected diabetics. Latencies of the F wave were measured, corrected for different lengths of the upper extremity, and used for computation of nerve conduction velocity. In comparison with conventional motor nerve conduction velocities the F wave latencies showed a more pronounced difference between the normal and the pathological (diabetic) range. The F wave nerve conduction velocities also varied less than conventional nerve conduction velocities. The explanation for this might be that the F wave recordings are the result of a full anti- and orthodromic impulse propagation which travels 5 to 6 times further than the impulse measured with conventional nerve conduction velocity methods. Therefore small delays of nerve conduction will be amplified and can be better recognized by F wave latency measurements. The present findings suggest that F wave latencies may be more sensitive than conventional nerve conduction velocities in evaluating mild cases and in identifying the initial phases of neuropathies.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European archives of psychiatry and clinical neuroscience 227 (1979), S. 207-212 
    ISSN: 1433-8491
    Keywords: Schizophrenia ; Hemodialysis ; β-Endorphin ; Schizophrenie ; Haemodialyse ; β-Endorphin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 3 Patienten mit chronischer Schizophrenie wurden Therapieversuche mit Haemodialyse durchgeführt. Es handelte sich um Schwerkranke, die seit über 10 Jahren dauerhospitalisiert waren und auf konventionelle somalische Behandlungen nicht angesprochen hatten. Die psychopathologische Beurteilung erfolgte unter Verwendung der IMPS-BPRS- und NOSIE-Skala. Nach einer Serie von 12 (in einem Fall 11) Haemodialysen konnte in keinem der Fälle eine deutliche Besserung nachgewiesen werden; in zwei von ihnen kam es hingegen zu einer Verschlechterung. Dieser Befund ist im Widerspruch zu den positiven Resultaten von Wagemaker und Cade. Für eine endgültige Beurteilung sind allerdings noch weitere Studien erforderlich.
    Notes: Summary Therapeutic trials with hemodialysis have been performed in three cases of chronic schizophrenia. The severely ill patients had been hospitalized for more than ten years and had not responded to different types of conventional somatic treatment. Psychopathology was evaluated by use of the IMPS, BPRS, and NOSIE scales. No improvement could be observed as a consequence of 12 (11 in one case) hemodialysis treatments. Rather, some deterioration occurred in two of the patients. This result is not in accord with the markedly positive findings of Wagemaker and Cade (1977). However, further studies appear necessary to render final conclusions.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European archives of psychiatry and clinical neuroscience 224 (1977), S. 141-149 
    ISSN: 1433-8491
    Keywords: Space perception ; Information theory ; Sensory information transfer ; Vestibular apparatus ; Wahrnehmung im Raum ; Informationstheorie ; Informationsübertragung ; Vestibularapparat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 1. Die Wahrnehmung der Lage im Raum bei seitlicher Kippung wurde bei 8 Versuchspersonen mit der Methode der „absoluten Schätzung“ informationstheoretisch untersucht. Eine erste Analyse zeigte, daß jeder Versuchsperson mindestens 1000 Reize verabreicht werden mußten, um bei 36 Reizkategorien zu statistisch gesicherten Werten zu gelangen. 2. Da dies zu lange Versuchsdauern zur Folge hat, wurden normierte Teilversuche zusammengefaßt. Zu kleine Reizzahlen ergeben aus statistischen Gründen zu hohe Informationsübertragung. Die statistisch gesicherte Informationsübertragung bei seitlicher Kippung beträgt im Durchschnitt 3,0 bit/Reiz. 3. Die Untersuchung der Informationsübertragung in verschiedenen Bereichen der Reiz-Antwort-Beziehung (Teiltransinformation) zeigt, daß nur im Bereich der Vertikalen mit Kopf nach oben mehr Information übertragen wird als in allen anderen Bereichen; dies steht im Gegensatz zur visuellen Wahrnehmung der Orientierung von Linien. 4. Die Reiz-Antwort-Beziehung zeigt eine leichte Abweichung von der Linearität: Auslenkungen aus der vertikalen Stellung mit Kopf nach unten werden bis zu einem Auslenkungswinkel von etwa 70° nach jeder Seite unterschätzt; Auslenkungen aus der vertikalen Stellung mit Kopf nach oben werden zunächst bis zu einem Auslenkungswinkel von 10° nach jeder Seite unterschätzt, dann aber bis zu einem Winkel von 70° nach jeder Seite überschätzt.
    Notes: Summary (1) With eight human subjects, the perception of position in space during lateral tilt was studied by a method of absolute judgement. A preliminary analysis showed that each subject required 1000 stimuli, with 36 stimulus categories, to attain statistical significance. (2) Since it would be hard to experiment with such long durations, normalized experiments were pooled. The average information transfer was 3.0 bit/stimulus. (3) A closer look at the information transmission in various portions of the stimulus-response relationship (partial information transfer) revealed that near the vertical, with the head uppermost, there is more information transmission than in all other positions. This is in contrast to the visual perception of line orientation. (4) The stimulus-response relationship shows a small nonlinearity. Deviations of the body position from the vertical, with the head down, are underestimated up to 70° away from the vertical; deviations from the vertical with the head uppermost are underestimated up to 10° away from the vertical but overestimated up to 70°.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Agroforestry systems 47 (1999), S. 123-138 
    ISSN: 1572-9680
    Keywords: Canavalia ensiformis ; Crotalaria orchroleuca ; Dolichos lablab ; farmer participatory research ; Mucuna pruriens ; soil fertility management
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Researchers worked with farmers in eastern Uganda to develop alternatives for soil management using crotalaria (Crotalaria ochroleuca), mucuna (Mucuna pruriens var. utilis), lablab (Dolichos lablab), and canavalia (Canavalia ensiformis) as green manures in short-term fallows. The participatory research was part of a community-based approach for systems improvement. Grain yields of maize (Zea mays) and bean (Phaseolus vulgaris) following one season of crotalaria fallow were 41% and 43%, respectively, more than following a two-season weedy fallow. Grain yields of maize following a one-season fallow with mucuna and lablab were 60% and 50% higher, respectively, as compared with maize following maize. Maize and bean yield were more, although effects were small, during the second and third subsequent seasons, indicating probable residual effects of the green manures. Mucuna and lablab were successfully produced by intersowing into maize at three weeks after sowing maize, although the yields of the associated maize crop were reduced by 24% to 28%. Farmers estimated the labor requirements for mucuna and lablab to be less than for crotalaria. Farmers independently experimented on how these species can be integrated into banana (Musa spp.), coffee (Coffea robusta), sweet potato (Ipomoea batatas), and cassava (Manihot esculenta) production systems. Farmers reported that the beneficial effects of the green manures included higher food-crop yields; weed suppression; improved soil fertility, soil moisture, and soil tilth; and erosion control. Mucuna and lablab were preferred because of reduced labor requirements and increased net benefits compared with continuous cropping. Farmer participation in the green manure research resulted in efficient generation and adaptation of green manure technology now being promoted in eastern and central Uganda.
    Type of Medium: Electronic Resource
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