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  • 1
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract  It is generally accepted that early human prostate cancers reveal higher androgen dependency than do advanced ones. In the present study, we examined whether the animal model of prostate cancer has already lost androgen dependency at the early stages of carcinogenesis. At experimental week 46, androgen deprivation was induced in rats and the incidences of atypical hyperplasia and cancer were examined in the ventral, dorsolateral prostate, coagulating glands, and seminal vesicles. Androgen deprivation significantly lowered the incidence of atypical hyperplasia in all four organs. As for the incidence of cancer, no significant differences were observed in the coagulating glands and seminal vesicles. Regarding atypical hyperplasia, androgen deprivation significantly decreased the proliferative cell nuclear antigen labeling index in the coagulating gland and seminal vesicles. The presence of cancer was also decreased in the coagulating gland but not in the seminal vesicles. With control group specimens, more intense staining of androgen receptor was observed in atypical hyperplasias than in cancers. Compared with the atypical hyperplasias, the cancers revealed low androgen dependency at the early stages of carcinogenesis. The cancers in the seminal vesicles also revealed higher androgen independency than did those in the coagulating gland.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 86 (1999), S. 5726-5732 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Co-cluster-assembled films have been prepared using a size-controllable cluster beam deposition system, by which monodispersed Co clusters with a mean diameter, d=6–13 nm are available. Their morphology and magnetic properties have been studied by scanning electron microscopy (SEM), small-angle x-ray scattering (SAXS) and magnetization measurements. The SEM images show that the film has a porous structure consisting of fine grains without a columnar texture and its density is about 25% of the bulk Co. The SAXS measurements indicate that monodispersivity of the incident clusters is maintained through their assembling process only for d=13 nm. All the specimens exhibit ferromagnetic behavior at room temperature and the magnetic coercive field Hc rapidly increases with decreasing temperature: Hc=168 kA/m (2.1 kOe) at 5 K. Such an enhancement in Hc is ascribed to the exchange anisotropy which arises from the antiferromagnetic Co–oxide layers covering the Co clusters, and to the assemblies of single-domain ferromagnetic clusters with the structure modification and magnetic interaction among them. The monotonic increase in Hc at 300 K with increasing d is simply understood in terms of the single-domain particle theory. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 85 (1999), S. 4400-4402 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The relationship between the mean hyperfine field of the residual intergranular amorphous phase 〈Bhf〉 and the coercivity Hc in various nanocrystalline soft magnetic samples has been investigated in order to clarify the effect of the spontaneous magnetization in the grain boundary region on their magnetic softness. Nanocrystalline samples with various 〈Bhf〉 values were prepared by annealing an amorphous Fe91Zr7B2 precursor for periods of 60 s–108 ks, at temperatures of 823–973 K. Hc shows a clear tendency to decrease with increasing 〈Bhf〉 or decreasing volume fraction of the residual amorphous phase. These effects of the residual amorphous phase on Hc are well understood within the framework of our extended two-phase random anisotropy model where both the exchange stiffness constant and volume fraction of the grain boundary phase are relevant to the exchange correlation length. Our results indicate that the exchange stiffness constant of the intergranular region varies as the square of the spontaneous magnetization of the residual amorphous phase. A small exchange stiffness constant on the order of 10−13 J/m is predicted for the residual amorphous phase in the Fe–Zr–B alloy. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd.
    Journal of metamorphic geology 16 (1998), S. 0 
    ISSN: 1525-1314
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: CHIME (chemical Th–U-total Pb isochron method) monazite ages were determined for gneisses and granitoids from the eastern and western parts of the Ryoke belt separated by about 500 km. The monazite ages for the gneisses are concentrated between 102 and 98 Ma, and are interpreted as the time of monazite formation under lower amphibolite facies conditions. The peak metamorphism seems to be contemporaneous with the emplacement of the geologically oldest plutons that are dated at c. 95 Ma in both the eastern and western parts. In the eastern part plutonism continued from c. 95 Ma to c. 68 Ma at intervals of 2–10 Ma, whereas in the western part it ceased at c. 85 Ma. The CHIME monazite ages agree well with the relative age of granitoids derived from intrusive relationships of granitoids in both parts. These lines of evidence are incompatible with a current view that the plutonometamorphism in the Ryoke belt becomes younger towards the east. The CHIME monazite ages, coupled with available data on the depth at which the Ryoke metamorphism took place and the emplacement of individual plutons, show that the western part was eroded more rapidly (about 1.5 mm year−1) than the eastern part (about 0.8 mm year−1) over the time span from 91 to 85 Ma. The denudation rates agree well with those in active orogenic belts like the Alps and Himalayas.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 79 (1996), S. 6270-6272 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have investigated the local structural anisotropy of Tb/Fe multilayers using linear polarized synchrotron radiation. X-ray absorption measurements were performed at Fe K edge (7.1 keV) using normal and glancing angle incident photon. From the Fe extended x-ray absorption fine structure (EXAFS), the local structural anisotropy was found for all multilayers as a slight difference of oscillation amplitude between the two incident directions. From the Fourier transformed EXAFS spectra, it is found that the local structural anisotropy shows the maximum at bilayer period of about 1 nm, where perpendicular magnetic anisotropy also shows the maximum value in various rare-earth/transition metal multilayers. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The structure, soft magnetic properties, magnetostriction, grain size and volume fraction of the residual amorphous phase have been studied for an amorphous Fe91Zr7B2 alloy annealed for periods of 60 s–1080 ks, at temperatures of 823–973 K. The highest permeability (at 1 kHz and 0.4 A/m) 31,000 and smallest coercivity 4.2 A/m are obtained for the sample annealed at 923 K for 60 s, where a small grain size (≈12 nm) and about 35% of the residual amorphous phase are measured. The coercivity of the nanocrystalline alloy varies as the 3rd power of the grain size, corresponding to the case where the magnetically coupled region has a dimensionality between two and three. This slightly low dimensionality is presumed to be due to the alignment of the magnetization in the sample plane. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 73 (1998), S. 2917-2919 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: High-quality GaAs epilayers with dislocation densities of 1.2×106 cm−2 on (100)Si substrates have been obtained by insertion of an InGaAs strained interlayer combined with thermal cycle annealing instead of strained layer superlattices. All the layers were grown by low-pressure metalorganic vapor phase epitaxy. The threading dislocation density near the surface of 4 μm thick GaAs was measured by plan-view transmission electron microscopy. The threading dislocation density was found to be very sensitive to the In composition of the interlayer and the specifics of thermal cycle annealing. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 73 (1998), S. 1460-1462 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We report emission from individual quantum dots excited by tunneling current injection using a scanning tunneling microscope (STM). By scanning the STM tip above the self-assembled InAs quantum dots, a spatially resolved scanning tunneling luminescence (STL) image was measured, which contained a fluorescent circular region with a diameter of 50 nm originating from a single InAs quantum dot. It was found that the spatial resolution of the STL system was about 40 nm, which is mainly due to lateral diffusion of holes injected into a GaAs capping layer grown at low temperature (480 °C). We also obtained STL spectra with a sharp single luminescent peak from a single InAs quantum dot. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 67 (1995), S. 1369-1371 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The nanostructural formation kinetics in a soft magnetic Fe80Nb6B14 alloy have been investigated by means of differential scanning calorimetry, thermogravimetric analysis and transmission electron microscopy. Unlike nanocrystalline Fe–Zr–B soft magnetic alloys, where the nanocrystallite formation is governed mostly by a nucleation and growth mechanism, the nanostructural formation mechanism in the Fe–Nb–B alloy shows a change in the fraction transformed range 0.1–0.2. The first- and second-stage nanostructural formation processes have been described by the nucleation and growth and grain-growth models, respectively. This two-stage nature in the nanostructural formation kinetics can be attributed to a high population density of the primary bcc nuclei. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 66 (1995), S. 385-387 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Experiments to generate a thin composite Fe-Ag film employing a sputter-gas-aggregation process are described. The magnetic properties are studied at low temperatures. In addition, the morphology is determined by high-resolution transmission electron microscopy and the structure by using x-ray diffraction and XAFS. Small clusters of about 11 A(ring) in diameter are highly dispersed in an Ag matrix. They show the characteristics of interacting superparamagnets. © 1995 American Institute of Physics.
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