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Digitale Medien

Inhibitory effects of selenium, vitamin A and butylated hydroxytoluene on in vitro growth of human tongue cancer cells (1995)

Inoue, I. ; Yamamoto, Y. ; Takasaki, T. ; [weitere]

Springer

European archives of oto-rhino-laryngology and head & neck 252 (1995), S. 509-512

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ISSN: 1434-4726

Schlagwort(e): Selenium ; Vitamin A ; Butylated hydroxytoluene ; Chemoprevention ; Human tongue cancer cells in vitro

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract The effects of vitamin A, selenium and butylated hydroxytoluene (BHT) on the growth of a human tongue cancer cell line were examined in monolayer cell cultures. A colony-forming assay showed a 50% reduction in the survival rate of the cell line at a concentration of 2.6 μg/ml selenium, 60 I μg/ml vitamin A and/or 38 μg/ml BHT. Relatively low concentrations of selenium markedly inhibited glucose consumption. Flow cytometric analysis with both fluorescein-isothiocyanate-labelled bromodeoxyuridine monoclonal antibody and propidium iodide demonstrated an increase in S-phase fractions 1 day after the addition of selenium, increased GO/G1 phase fractions in the presence of vitamin A and increased G2M phase fractions when BHT was added. These results suggest that these compounds inhibit DNA synthesis of in vitro human tongue cancer cells by different mechanisms.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF02114762

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Digitale Medien

Quantum limit for the atom-light interferometer (1995)

Jacobson, J. ; Björk, G. ; Yamamoto, Y.

Springer

Applied physics 60 (1995), S. 187-191

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ISSN: 1432-0649

Schlagwort(e): 42.50.Dv ; 03.75.Dg ; 03.75.Fi

Quelle: Springer Online Journal Archives 1860-2000

Thema: Physik

Notizen: Abstract The standard quantum limit is calculated for the atom-light interferometer. It is shown that the smallest detectable phase is $$\delta \phi _{\min } = \frac{1}{2}[N_{atoms} + 4N_{photons} )/N_{atoms} N_{photons} ]^{1/2} .$$ Therefore, in practical experiments, the accuracy is limited by the square root of the number of atoms. We propose a novel correlated atom-photon state interferometer which makes a transition to the Heisenberg limit, δφmin ∝ 1/N atoms, as the atoms approach a Bose condensate. Such an interferometer may serve as a sensitive probe of the onset of Bose condensation. Finally, we point out that the correlated atom-photon state preparation scheme we propose may be used in a different way to approach the Heisenberg limit for non-Bose-condensed atoms.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01135861

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