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  • 1995-1999  (3)
  • 5HT2 receptor  (1)
  • Chaetomorpha  (1)
  • Dynamic control  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Effects of antidepressants and antipsychotics on the 5HT2 receptor-mediated signal transducing system in human platelets (1995)
    Springer
    Psychopharmacology 121 (1995), S. 428-432 
    Details
    ISSN: 1432-2072
    Keywords: 5HT2 receptor ; 3H-Ketanserin binding ; Ca2+ ; Platelet shape change ; 3H-Paroxetine binding
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The IC50 values of the antidepressants amoxapine, mianserin, desipramine, clomipramine and imipramine, and the antipsychotics spiroperidol, chlorpromazine, levomepromazine and haloperidol for3H-ketanserin binding, 5HT-induced intracellular Ca2+ increase, 5HT-induced shape change and3H-paroxetine binding in human plateletes were measured and the correlations of each parameter were examined. Results were as follows. Both the antidepressants and the antipsychotics had inhibitory effects on3H-ketanserin binding, 5HT-induced intracellular Ca2+ increase and 5HT-induced shape change and there were significant positive correlations between the IC50 values of these three parameters. On the other hand, there were no significant correlations between the IC50 values in3H-paroxetine binding and those in the other three parameters. These results suggest that3H-ketanserin binding, 5HT-induced intracellular Ca2+ increase and 5HT-induced shape change are useful and reliable tools for the assessment of the effects of the antidepressants and the antipsychotics on the 5HT2 receptor-mediated signal transducing system in human platelets.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02246490
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Assembly of cortical microtubules during cold treatment of the coenocytic green alga, Chaetomorpha moniligera (1995)
    Springer
    Planta 196 (1995), S. 190-192 
    Details
    ISSN: 1432-2048
    Keywords: Chaetomorpha ; Cold treatment ; Cortical microtubule ; Immunofluorescence ; Microtubule assembly
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The effects of cold treatment on the cortical microtubules (MTs) of Chaetomorpha moniligera Kjellman were investigated by immunofluorescence microscopy. Cortical MTs in Chaetomorpha thallus are arranged longitudinally. In this study, 70–75% of MTs disassembled within 4 h on ice while the others remained stable under these conditions. Reticulate background immunofluorescence, assumed to indicate the presence of a tubulin monomer, was distributed about the stable MTs. Immunofluorescence was prominent in only 50% of the cells. Tubulin polymerization was noted where the background and MT immunofluorescence was strong. New MTs grew transversely as single strings or clusters from the sides of MTs after cold treatment for 4 h and elongated with time to take on a reticulate form at 24 h. The significance of this tubulin polymerization under cold treatment is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00193233
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Dynamic control of redundant manipulators using the artificial potential field approach with time scaling (1999)
    Springer
    Artificial life and robotics 3 (1999), S. 79-85 
    Details
    ISSN: 1614-7456
    Keywords: Artificial potential field approach ; Dynamic control ; Redundant manipulator ; time-base generator ; Time-scale transformation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract This paper proposes a new method for the dynamic control of redundant manipulators via the artificial potential field approach. In the artificial potential field approach, the goal is represented by an artificial attractive potential field and the obstacles by corresponding repulsive field, so that the trajectory to the target can be associated with the unique flow-line of the gradient field through the initial position and can be generated via a flow-line tracking process. This approach is suitable for real-time motion planning because of its simplicity and smaller computational time than other methods based on global information about the task space. However, little attention has been paid to the control of the dynamic behavior of the trajectories generated. The proposed method is based on the artificial potential field approach with a combination of a time-scale transformation and a time-base generator which works as a time-scale compressor and can control the dynamic behavior of the robot without any change in the form of the designed controller itself. It can also be applied to the dynamic motion planning problem of redundant manipulators. The effectiveness of the proposed method is verified by computer simulations for a three-joint planar manipulator.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02481251
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    Paper (German National Licenses)
    Fulltext
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