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  • 1995-1999  (3)
  • Apocrine secretion  (1)
  • Key words Cervical myelopathy  (1)
  • Key wordsPolygonum hydropiper  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Der Orthopäde 25 (1996), S. 496-504 
    ISSN: 1433-0431
    Keywords: Schlüsselwörter Zervikale Spondylose ; Myelopathie ; Pathoanatomie ; klinische Symptome ; Key words Cervical myelopathy ; Patho-anatomy ; Clinical symptoms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Clinical symptoms and patho-anatomic changes in cervical myelopathy due to spondylotic changes are described. The leading symptoms are numbness and clumsiness of upper and lower extremity, mostly combined with gait disturbances. Muscle wasting primarily on the upper extremity leads to the myelopathic hand. Cervical myelopathy can be classified into five main groups: 1. Spastic tetraparesis with numbness and hyperreflexivity of upper and lower extremity. The majority of patients present with the myelopathic hand. 2. Spastic paraparesis with lesion below C6. 3. Spastic tetraparesis, mild or moderate, with deltoid muscle paresis. 4. Amyotrophic myelopathic hand with mild long tract signs. 5. Central cord syndrome due to cervical spondylosis combined with trauma. From the therapeutic aspect, conservative treatment is often unsuccessful. It is important to relieve pressure on the myelon, and decompressive procedures, especially posterior laminoplasty techniques, are required. Earlier surgery provides better results.
    Notes: Zusammenfassung Das klinische Erscheinungsbild der zervikalen Spondylose mit Myelopathie wird dargestellt. Die achsennahen Symptome wie Zervikalgie sind auf die radiologisch feststellbaren Veränderungen zurückzuführen. Periphere Symptome wie Radikulopathien können hinzukommen, wenn die lateralen Anteile des Spinalkanals eingeengt werden. Die Deltoideusparese Grad ≤ 3 (MMT) ist die häufigste Symptomatik von klinischer Bedeutung, wenn nur ein einzelner Muskel betroffen ist, die von der zervikalspondolytischen Radikulopathie verursacht wird. Bei der zervikalen Myelopathie stehen aber nicht Schmerz, sondern Funktionsstörungen im Vordergrund. Taubheitsgefühle an oberen und unteren Extremitäten sowie Gangstörungen sind Frühzeichen. Muskelatrophien werden vor allem an der oberen Extremität beobachtet und führen häufig zur sog. myelopathischen Hand. Der zervikale Myelopathie läßt sich in verschiedene Formen unterteilen: 1. spastische Tetraparese mit Symptomen der oberen und unteren Extremität, 2. spastische Paraparese bei Kompressionen unterhalb C6, 3. spastische Tetraparese mit Parese des M. deltoideus, 4. atropische Form der myelopathischen Hand mit Beteiligung der langen Bahnen, 5. zentrales Rückenmarksyndrom bei zervikaler Spondylose und Traumaanamnese. Therapeutisch sind konservative Maßnahmen wenig erfolgversprechend, es empfiehlt sich dekompressive Chirurgie. Die Prognose ist um so besser, je früher die Dekompression erfolgt.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Plant cell reports 18 (1999), S. 759-763 
    ISSN: 1432-203X
    Keywords: Key wordsPolygonum hydropiper ; Flavanol ; Procyanidin ; Cell suspension culture
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Cultured Polygonum hydropiper cells maintained in Murashige and Skoog (MS) medium supplemented with 10–6 m 2,4-D, 10–6 m kinetin, 0.1% casamino acids and 3% sucrose were transferred to medium containing a higher concentration of calcium chloride (15 mm). The content of flavanols in the cells on the 6th day was approximately twice that of the control culture (31.9–60.7 mg/g dry wt). However, the contents of other secondary metabolites such as chlorogenic acid and gallic acid were not changed. The levels of flavanols in the culture medium remained unchanged throughout the 21-day culture period. Of the the inorganic components supplemented to the culture medium , only elevated levels of calcium chloride induced an increase in flavanol contents of the cells. The results indicated that the elevated concentration of calcium in the culture medium played an important role in activating the accumulation of flavanols.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 285 (1996), S. 501-507 
    ISSN: 1432-0878
    Keywords: Key words: Harderian gland ; Apocrine secretion ; Myoepithelial cell ; NaF+AlCl3 ; Carbachol ; Papaverine ; Rat (Sprague Dawley)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. Harderian glands of male albino rats were stimulated with secretagogues and examined by transmission and scanning electron microscopy for the purpose of studying the apocrine secretory mechanism. Rats in the control group were perfused with standard HEPES-buffered Ringer’s solution. Their glandular endpieces showed wide lumina that contained few secretory materials; spontaneous exocytosis was sometimes observed. However, there were no features suggestive of an apocrine secretory mechanism or myoepithelial cell contractions. After stimulation with NaF+AlCl3 or carbachol in HEPES-buffered Ringer’s solution, the rats shed ”bloody tears” and the glandular lumina were jammed with apical protrusions, cytoplasmic material and secretory products. The basal surface of the glandular cells showed bulging caused by myoepithelial cell contraction. Perfusion with HEPES-buffered Ringer’s solution containing papaverine inhibited secretagogue-induced myoepithelial cell contraction but not the enhanced secretory activities of the glandular cells. The present results demonstrate that the Harderian gland of the rat can release secretory material not only by exocytosis, but also by an apocrine mechanism under stimulating conditions, and that myoepithelial cell contraction may not be involved in causing apical protrusion in the glandular cells.
    Type of Medium: Electronic Resource
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