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  • 1995-1999  (4)
  • Axonal dystrophy  (2)
  • Dynamic light scattering  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Calcitonin gene-related peptide- and substance P-immunoreactive axons in the nucleus gracilis of the rat with special reference to axonal dystrophy: light and electron microscopic observations (1995)
    Springer
    Acta neuropathologica 90 (1995), S. 347-355 
    Details
    ISSN: 1432-0533
    Keywords: Key words Nucleus gracilis ; Axonal dystrophy ; Calcitonin gene-related peptide ; Substance P ; Immunoelectron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Calcitonin gene-related peptide (CGRP) and substance P (SP)-immunoreactive (IR) axons in the nucleus gracilis of normal rats (1–15 months of age) were studied by light and electron microscopy. Besides many CGRP-IR and SP-IR varicosities with normal appearance, we found a few swollen (nearly round or oval) varicosities with either CGRP or SP immunoreactivity. Swollen CGRP-IR varicosities were more frequently seen than SP-IR ones, appearing from 3 months of age and increasing in number and size (up to approximately 25 μm in diameter) with advancing age. At the electron microscopic (EM) level, CGRP-IR and SP-IR swollen varicosities showed dystrophic changes, i.e., many membranous dense bodies, and proliferation of microtubules and neurofilaments. CGRP-IR or SP-IR dystrophic axons also contained many mitochondria and sometimes made synaptic contacts with nonreactive dendrites (occasionally with non-IR axons). These findings suggest that the dystrophic CGRP and SP axonal profiles represent a functionally distinct subpopulation of axonal dystrophy in the nucleus gracilis and use CGRP or SP as a neuroactive substance. Using a double-immunostaining method, many of normal CGRP-IR axons were identified to be SP-IR. However, no single dystrophic varicosity was found to contain both CGRP and SP immunoreactivities. These findings suggest that CGRP and SP afferents are independently affected and progress to dystrophic changes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00315008
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Calcitonin gene-related peptide- and substance P-immunoreactive axons in the nucleus gracilis of the rat with special reference to axonal dystrophy: light and electron microscopic observations (1995)
    Springer
    Acta neuropathologica 90 (1995), S. 347-355 
    Details
    ISSN: 1432-0533
    Keywords: Nucleus gracilis ; Axonal dystrophy ; Calcitonin gene-related peptide ; Substance P ; Immunoelectron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Calcitonin gene-related peptide (CGRP) and substance P (SP)-immunoreactive (IR) axons in the nucleus gracilis of normal rats (1–15 months of age) were studied by light and electron microscopy. Besides many CGRP-IR and SP-IR varicosities with normal appearance, we found a few swollen (nearly round or oval) varicosities with either CGRP or SP immunoreactivity. Swollen CGRP-IR varicosities were more frequently seen than SP-IR ones, appearing from 3 months of age and increasing in number and size (up to approximately 25 μm in diameter) with advancing age. At the electron microscopic (EM) level, CGRP-IR and SP-IR swollen varicosities showed dystrophic changes, i.e., many membranous dense bodies, and proliferation of microtubules and neurofilaments. CGRP-IR or SP-IR dystrophic axons also contained many mitochondria and sometimes made synaptic contacts with nonreactive dendrites (occasionally with non-IR axons). These findings suggest that the dystrophic CGRP and SP axonal profiles represent a functionally distinct subpopulation of axonal dystrophy in the nucleus gracilis and use CGRP or SP as a neuroactive substance. Using a double-immunostaining method, many of normal CGRP-IR axons were identified to be SP-IR. However, no single dystrophic varicosity was found to contain both CGRP and SP immunoreactivities. These findings suggest that CGRP and SP afferents are independently affected and progress to dystrophic changes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00315008
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Kinetic study of the formation reaction of colloidal silica spheres in microgravity using aircraft (1999)
    Springer
    Colloid & polymer science 277 (1999), S. 474-478 
    Details
    ISSN: 1435-1536
    Keywords: Key words Reaction kinetics in microgravity ; Colloidal silica spheres ; Polymerization ; Transmitted-light intensity ; Dynamic light scattering
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Polymerization reactions of colloidal silica spheres via the hydrolysis and dehydration processes of tetraethyl orthosilicate with ammonia and a tiny amount of water in ethyl alcohol have been studied in microgravity by the parabolic flights of a MU-300 rear-jet aircraft. Induction periods and polymerization rates are determined by fast-scanning transmitted-light-intensity measurements and the fast-scanning dynamic light-scattering method. Direct observation of the reaction mixtures is also made with a charge-coupled device video camera. Reproducible and reliable data are obtained in microgravity compared with those in gravity. Increases in the induction times and decreases in the polymerization rates are observed in microgravity compared with those in gravity. One of the main reasons for these observations is the fact that the translational Brownian movement of the reactants and/or product spheres is free from downward translational movement in microgravity. Very weak convection of the reaction suspensions in microgravity is another important factor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003960050411
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Kinetic study of the formation reaction of colloidal silica spheres by transmitted-light-intensity and dynamic light-scattering measurements (1999)
    Springer
    Colloid & polymer science 277 (1999), S. 483-487 
    Details
    ISSN: 1435-1536
    Keywords: Key words Colloidal silica formation ; Kinetics of polymerization ; Transmitted-light intensity ; Dynamic light scattering
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Kinetic analyses of the formation reaction of colloidal silica spheres which are synthesized from ethyl silicate (EtSi), ammonia and a trace of water in ethanol are made by the transmitted-light-intensity and dynamic light-scattering methods. Sphere size versus time profiles from the two methods agree well especially at the beginning of the reaction. The polymerization starts after a certain induction time (t i) ranging from several tens of seconds to several minutes. t i increases as the concentrations of NH3, EtSi and/or H2O decrease. The apparent rates of the reaction, v ′ are estimated from the reciprocal periods between the intersections of the linear line with the initial and final horizontal lines in the cube root of the absorbance versus time plots. Log v ′ increases linearly with slopes of 1, 2 and 0.5 as the logarithms of the concentrations of EtSi, NH3 and/or H2O increase, respectively. These results are consistent with the assumption proposed earlier that the polymerization mechanism of the formation of the small preliminary particles is followed by their coalescence to form large silica spheres.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003960050413
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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