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  • 1995-1999  (2)
  • Chloride  (1)
  • Complement system  (1)
  • Capillary leak syndrome Critical illness Sepsis Blood volume determination Bioelectric impedance Osmotic pressure
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Material
Years
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Alteration of anion gap during almost total plasma replacement with synthetic colloids in piglets (1999)
    Springer
    Intensive care medicine 25 (1999), S. 1287-1290 
    Details
    ISSN: 1432-1238
    Keywords: Key words Hydroxyethyl starch ; Modified fluid gelatin ; Chloride ; Anion gap ; Acid base ; Saline
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In ten piglets (body weight 8.2–11.6 kg), acid base, electrolyte and anion gap changes were investigated during almost total plasma replacement with hydroxyethyl starch (HES) and modified fluid gelatin (GEL) in saline solution using a cell saver autotransfusion technique. During the study, there were only moderate acid base changes, but marked disturbances in anion balance. At study end, the mean chloride concentration was significantly higher (mmol/l: normal values 97–108, HES 116 ± 1.5, GEL 108 ± 1.1, p 〈 0.01) and the mean anion gap was significantly lower in the HES group in comparison to the GEL group (mmol/l: normal values 5–14, HES 3 ± 1.7, GEL 11.9 ± 0.9, p 〈 0.01). It is concluded that plasma replacement with electroneutral HES, but not with negatively charged GEL, can lower the anion gap irrespective of the underlying disease. This can be misleading when the anion gap is used for differential diagnosis of metabolic acidosis in patients after large volume infusion of synthetic colloids.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340051059
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Septic shock after liver transplantation for Caroli's disease: clinical improvement after treatment with C1-esterase inhibitor (1999)
    Springer
    Intensive care medicine 25 (1999), S. 1017-1020 
    Details
    ISSN: 1432-1238
    Keywords: Key words C1-esterase inhibitor ; Complement system ; Sepsis ; Liver transplantation ; Caroli's disease ; Colloid osmotic pressure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The extent of complement and contact activation is related to outcome in sepsis. A low functional index of their main blocker C1-esterase inhibitor (C1-INH) is considered as a relative deficiency of C1-INH and might contribute to the development of fatal complications in the intensive care unit. The first results of therapeutic intervention with C1-INH concentrate in septic shock are promising. We report on our experience of C1-INH concentrate administration in a young woman with Caroli's disease as ultimate rescue therapy for septic shock with capillary leakage syndrome after combined liver and kidney transplantation. No focus of infection was detectable and thus surgical intervention was not indicated. Antibiotic therapy at that time included vancomycin, tobramycin, meropenem and fluconazol. Hemodynamic stabilization occurred within hours after administration of C1-INH concentrate. Simultaneously a reduction in vasopressor medication was possible and negative fluid balance was achieved.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340051000
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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