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  • 1995-1999  (3)
  • Chemistry  (2)
  • Living donor
  • Multicatalytic proteinase
  • Proteasome
  • 1
    Electronic Resource
    Electronic Resource
    One-way donor-recipient HLA-matching as a risk factor for graft-versus-host disease in living-related liver transplantation (1998)
    Springer
    Transplant international 11 (1998), S. S383 
    Details
    ISSN: 1432-2277
    Keywords: Key words One-way matching ; Human leukocyte antigen ; Graft-versus-host disease ; Living donor ; Liver transplantation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Although one-way matching between an HLA-homozygous donor and a haploidentical recipient is a recognized risk factor in transfusion-associated graft-versus-host disease (GVHD), its impact in living-related liver transplantation (LRLT) has so far not been investigated. We present a case of fatal acute GVHD in our LRLT program that was attributed to one-way HLA matching between donor and recipient. Although the disappearance of donor cells in peripheral blood was suggested by genetic analysis, severe septicemia led to a fatal outcome. We further reviewed 280 LRLT cases and correlated one-way HLA matching with outcome. A total of 8 out of 280 donors (2.9 %) and 11 out of 278 recipients (4.0 %) were completely HLA homozygous in our LRLT program. Complete one-way HLA matching linked to GVHD was observed in four cases, including the present case. Although other contributing factors also need to be clarified, one-way HLA matching is a definite risk factor for GVHD in LRLT. We advocate caution before proceeding with one-way HLA donor-recipient combinations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001470050503
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Host-guest chemistry. The structure and proton disorder of the three-component crystal formed by 3(5)-methyl-4-nitropyrazole, (R, R)-(-)-trans-4,5-bis (hydroxydiphenylmethyl)-2,2-dimethyl-1,3-dioxolane and toluene (1996)
    Chichester : Wiley-Blackwell
    Journal of Physical Organic Chemistry 9 (1996), S. 611-618 
    Details
    ISSN: 0894-3230
    Keywords: Chemistry ; Theoretical, Physical and Computational Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The crystal structure at 200 K of the complex formed by the optically active host (R,R)-(-)-trans-4,5-bis(hydroxydiphenylmethyl)-2,2-dimethyl-1,3-dioxolane (2) and 4-nitro-5-methylpyrazole (1b) and toluene as guests was determined by x-ray analysis. Although only the NH protons corresponding to tautomer 1b were found in the structure, some anomalies in the bond angles involving the nitrogen atoms of the pyrazole ring suggested the presence of about 25% of a structure containing the 3-methyl-4-nitropyrazole tautomer (1a). This hypothesis was confirmed by 13C cross polarization magic angle spinning NMR spectroscopy.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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    Paper (German National Licenses)
  • 3
    Electronic Resource
    Electronic Resource
    Surface molecular motion in thin films of poly(styrene-block-methyl methacrylate) diblock copolymer (1995)
    Weinheim : Wiley-Blackwell
    Acta Polymerica 46 (1995), S. 476-482 
    Details
    ISSN: 0323-7648
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Thin films of poly(styrene-block-methyl methacrylate) diblock copolymer [P(St-b-MMA)] with thickness ca. 50 nm were prepared by a dip-coating method. The surface Tg for the P(St-b-MMA) thin film was evaluated on the basis of the temperature-dependent X-ray photoelectron spectroscopic (TDXPS) measurement. The temperature at which the surface composition started to change was defined as the glass transition temperature, Tg, at the surface region. It was revealed that the surface Tg for P(St-b-MMA) was much lower than that for its bulk sample. Also, the depth dependence of Tg for P(St-b-MMA) was investigated on the basis of the combination of TDXPS and the angular-dependent XPS (ADXPS) method. Tg for P(St-b-MMA) decreased with a decrease in distance from the outermost surface. The molecular weight dependence of the surface Tg for P(St-b-MMA) was more pronounced than that in the bulk sample, and that was expressed as a function of M-(0.45±0.02)n.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/actp.1995.010460612
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    Paper (German National Licenses)
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