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  • 1995-1999  (3)
  • Endothelial cells  (2)
  • Intake of energy and nutrients  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Veränderungen der Energie- und Nährstoffaufnahme der Bevölkerung im ersten Jahr der deutschen Einheit — Ergebnisse einer Modellstudie in Potsdam (1996)
    Springer
    European journal of nutrition 35 (1996), S. 150-156 
    Details
    ISSN: 1436-6215
    Keywords: Energie- und Nährstoffaufnahme ; Trends ; Bedeutung einzelner Lebensmittel-gruppen ; Modellstudie ; neue Bundesländer ; Intake of energy and nutrients ; trends ; importance of several food groups ; model study ; new German States
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Summary A nutritional model study was carried out in Potsdam from December 1990 until December 1991 involving 222 persons at the beginning. Changes of the energy and nutrient intake were evaluated. The trends established in 1991 — demonstrated by means of two specific trend parameters — have been discussed with regard to the results of the nutritional situation in the former GDR. First signs for an improvement of nutritional situation were visible (e.g., increase of consumption of vitamin A, ascorbic acid and calcium as well as decrease of consumption of energy and cholesterol).
    Notes: Zusammenfassung Eine von Ende 1990 bis Ende 1991 in Potsdam durchgeführte Modellstudie an anfangs 222 Personen wurde unter dem Aspekt von Veränderungen der Energie- und Nährstoffaufnahme ausgewertet. Die für 1991 ermittelten Trends — dargestellt durch 2 spezifische Trendparameter — wurden unter Beachtung von Ergebnissen über die Ernährungssituation in der ehemaligen DDR diskutiert. Ansätze zu einer Verbesserung der Ernährungssituation wurden sichtbar (z.B. Verzehrszunahmen bei Vitamin A, Vitamin C und Calcium sowie -abnahmen bei Energie und Cholesterin).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01622863
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Functional serotonin 5-HT1D receptors and 5-HT1Db receptor mRNA expression in human umbilical vein endothelial cells (1995)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 352 (1995), S. 580-582 
    Details
    ISSN: 1432-1912
    Keywords: Key words 5-Hydroxytryptamine (5-HT ; serotonin) ; 5-HT1D receptors ; 5-HT1Dβ receptors ; Endothelial cells ; Cyclic AMP
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pharmacological evidence has suggested the presence of 5-hydroxytryptamine (5-HT, serotonin), 5-HT1D receptors on endothelial cells but these receptors have never been identified unambiguously on this type of cells. We now report that human umbilical vein endothelial cells (HUVEC) express 5-HT1D receptors coupled to inhibition of cyclic AMP formation. 5-HT and the 5-HT1D receptor agonists 5-carboxamidotryptamine (5-CT) and sumatriptan were approximately equipotent at inhibiting forskolin-stimulated cyclic AMP accumulation in HUVEC (mean pEC50 7.6–8.2, maximal effect 30% inhibition). The 5-HT1A receptor agonist, 8-OH-DPAT was clearly less potent (pEC50 6.2) and less efficacious. The selective 5-HT1D receptor antagonist, GR127935 (1 nM) markedly inhibited the effect of 5-HT (apparent pKB 10.8). Reverse transcription-polymerase chain reaction analysis showed the mRNA for 5-HT1Dβ receptors to be expressed in HUVEC. These results demonstrate the presence of functional 5-HT1D receptors and the expression of 5-HT1Dβ receptor mRNA in HUVEC. They support the involvement of 5-HT1Dβ receptors in endothelial-mediated responses to 5-HT.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00169394
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Functional serotonin 5-HT1D receptors and 5-HT1Dβ receptor mRNA expression in human umbilical vein endothelial cells (1995)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 352 (1995), S. 580-582 
    Details
    ISSN: 1432-1912
    Keywords: 5-Hydroxytryptamine (5-HT, serotonin) ; 5-HT1D receptors ; 5-HT1Dβ receptors ; Endothelial cells ; Cyclic AMP
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pharmacological evidence has suggested the presence of 5-hydroxytryptamine (5-HT, serotonin), 5-HT1D receptors on endothelial cells but these receptors have never been identified unamiguously on this type of cells. We now report that human umbilical vein endothelial cells (HUVEC) express 5-HT1D receptors coupled to inhibitiion of cyclic AMP formatin. 5-HT and the 5-HT1D receptor agaonists 5-carboxamidotryptamine (5-CT) and sumatriptan were approximately equipotent at inhibiting forskolin-stimulated cyclic AMP accumulation in HUVEC (mean pEC50 7.6–8.2, maximal effect 30% inhibition). The 5-HT1A receptor agonist, 8-OH-DPAT was clearly less potent (pEC50 6.2) and less efficacious. The selective 5-HT1D receptor antagonist, GR127935 (1 nM) markedly inhibited the effct pf 5-HT (apparent pKB 10.8). Reverse transcription-polymerase chain reaction analysis showed the mRNA for 5-HT1Dβ receptors to be expressed in HUVEC. These results demonstrate the presence of functional 5-HT1D receptors and the expression of 5-HT1Dβreceptor mRNA in HUVEC. They support he involvement of 5-HT1Dβ receptors in endothelial-mediated responses to 5-HT.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00169394
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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