ISSN:
1432-1076
Keywords:
Key words Schimke immuno-osseous dysplasia
;
Spondylo-epiphyseal dysplasia
;
White-matter-lesions
;
Cerebrovascular complications
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Schimke immuno-osseous dysplasia is a multisystem disorder consisting of spondylo-epiphysial dysplasia, progressive renal insufficiency due to focal segmental glomerulosclerosis, and immunodeficiency. Cerebrovascular complications have only been described in five patients. Here we report a patient with prominent neurological symptoms most likely caused by transient ischaemic attacks. Conclusion Neurological symptoms consisted of re-peated brief spells of hemiparaesthesia, motoric aphasia and diplopia. MRI studies of the CNS revealed progressive white matter lesions. Morphological changes as well as neurological deficits are compatible with cerebral ischaemia.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004310050714
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