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  • 1995-1999  (3)
  • Pelargonium xhortorum  (2)
  • Local recurrence  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Volume of resection in patients treated with breast conservation for ductal carcinoma in situ (1998)
    Springer
    Annals of surgical oncology 5 (1998), S. 757-763 
    Details
    ISSN: 1534-4681
    Keywords: Age ; Intraductal breast carcinoma ; Breast ductal carcinoma in situ ; Volume of resection ; Breast conservation ; Local recurrence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: The optimal treatment of ductal carcinoma in situ (DCIS) is one of the most controversial issues in the management of breast cancer. Identification of factors that affect the risk of local recurrence is very important as the incidence of DCIS increases and the use of breast conservation becomes more widespread. Because the extent of resection may affect the relapse rate, we hypothesized that larger volumes of resection (VR) may account for the lower local recurrence rates we have previously found in elderly patients. Methods: Between 1978 and 1990, 173 cases of histologically confirmed DCIS were treated at MSKCC with breast conservation therapy. Of these, complete VR data were available for 126 cases. The VRs thus obtained were divided into two groups, 〈60 cm3 and ⩾60 cm3, and were evaluated for correlating factors. The patients were divided into three groups by age at diagnosis: younger than 40 years, 40 to 69 years, and 70 years or older. Results: The eldest group had a significantly greater proportion of large VRs (30%) as compared to the middle group (11%) and the youngest group (9%) (P=.03, x2). Although not statistically significant, the large VR group had a lower 6-year actuarial local recurrence rate (5.6%) than did the small VR group (21.3%) (P=.16, log-rank test). This trend was observed even though adjuvant radiotherapy was used less often in patients who had large VRs. Conclusion: Breast conservation surgery for DCIS in elderly patients is more likely to employ a large VR. This may explain, at least in part, the observation that elderly patients have a lower local recurrence rate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02303488
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  • 2
    Electronic Resource
    Electronic Resource
    Tissue-Specific Fatty Acid Composition of Glandular Trichomes of Mite-Resistant and -Susceptible Pelargonium xhortorum (1999)
    Springer
    Journal of chemical ecology 25 (1999), S. 955-968 
    Details
    ISSN: 1573-1561
    Keywords: Fatty acids ; geraniums ; glandular trichomes ; glycolipids ; Pelargonium xhortorum ; phospholipids ; ω5-unsaturated fatty acids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Anacardic acids, alkyl phenolic acids excreted by tall glandular trichomes of the garden geranium, Pelargonium xhortorum, confer small-pest resistance. Up to 90% of the trichome exudate from mite-resistant P. xhortorum inbreds consists of an unusual anacardic acid with an unsaturated omega-5 (ω5) alkyl chain. As fatty acids are biochemical precursors to anacardic acids, we examined by GC the fatty acid composition of leaves, pedicels, petals, sepals, mature seeds, and glandular trichomes from pest-resistant and pest-susceptible Pelargonium inbred lines to determine the localization of ω5-fatty acids within plant tissues. The fatty acid composition of lipid classes (galactolipids, phospholipids, and neutral lipids) extracted from glandular trichomes from mite-resistant pedicels were also examined. ω5-Fatty acids (16:1Δ11 and 18:1Δ13) were found only in the glandular trichomes from pest-resistant geraniums (27.2% in trichomes of pedicels) and were localized predominantly in the phospho- and galactolipids (phosphatidylinositol, 25.9%; phosphatidylcholine, 18.2%; monogalactosyldiglyceride, 15.5%; and diglactosyldiglyceride, 14.0%).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1020865322035
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  • 3
    Electronic Resource
    Electronic Resource
    Development of a mite bioassay to evaluate plant resistance and its use in determining regeneration of spider mite resistance (1996)
    Springer
    Entomologia experimentalis et applicata 81 (1996), S. 301-305 
    Details
    ISSN: 1570-7458
    Keywords: Pelargonium xhortorum ; host-plant resistance ; geraniums ; anacardic acids ; bioassay ; regeneration ; Tetranychus urticae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The zonal geranium (Pelargonium xhortorum) possesses tall glandular trichomes that secrete anacardic acids, a viscous, sticky exudate which has been suggested as the primary mechanism in two-spotted spider mite (Tetranychus urticae Koch) resistance. A new bioassay was developed using small Plexiglas® cylinders as chambers for evaluating the resistance of geranium leaves to the two-spotted spider mite. This bioassay was easy to prepare, required only 24 hours to conduct, exhibited no problems with desiccation, condensation, or mite accountability, and yielded reproducible results. This bioassay was then used to study the regeneration of resistance of attached geranium leaves after they were made mite-susceptible by removing the excreted anacardic acids with water. Washed leaves regained full resistance after 14 days.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00187039
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    Paper (German National Licenses)
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