ISSN:
1573-8221
Keywords:
epilepsy
;
subarachnoid hemorrhage
;
brain vessels
;
reactivity
;
endothelin
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Examination of the reactivity exhibited by the basilar artery of the brain in Krushinsky-Molodkina rats before and after an induced epileptiform seizure accompanied by subarachnoid hemorrhages showed increased contractility of this artery in response to endothelin-1 and its reduced sensitivity to ATP 24 h after the seizure. Such changes in the reactivity of brain vessels may contribute to the development of vasospasm and secondary ischemia of the brain after an epileptic seizure.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02446613
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