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  • 1
    Electronic Resource
    Electronic Resource
    Natural history of minute sessile colonic adenomas based on radiographic findings (1995)
    Springer
    Diseases of the colon & rectum 38 (1995), S. 268-272 
    Details
    ISSN: 1530-0358
    Keywords: Sessile adenoma ; Natural history ; Double-contrast barium enema ; Polypectomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: With the development of colonoscopy and double-contrast barium enema, detection of minute sessile coIonic adenomas has increased. We evaluated progression of these lesions radiologically and attempted to clarify the natural history. METHODS: A total of 125 minute sessile adenomas (≤5 mm in size) with histologic confirmation were examined by double-contrast barium enema at an interval of more than one year. The average follow-up period was 24 (range, 12–36; standard deviation, 9–4) months. To allow for differences in magnification, adenomas increasing in size by 2 mm or more were defined as growing, and the other lesions were defined as unchanged. RESULTS: Eighty-six adenomas showed no interval change in size. Four adenomas decreased 1 mm in size, and 27 adenomas increased 1 mm in size. The remaining eight adenomas (6 percent) increased by 2 or 3 mm in size. None of the adenomas showed any morphologic changes. There was also no difference in degree of histologic atypia between growing and unchanged adenomas. None of the adenomas developed into carcinomas during the follow-up period. CONCLUSIONS: These data show that most minute sessile adenomas remain unchanged in size and morphology over the long term. Accordingly, these adenomas probably should be followed up radiologically or endoscopically to avoid excessive polypectomy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02055600
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  • 2
    Electronic Resource
    Electronic Resource
    Inflammatory pseudotumor of the liver: Radiologic diagnosis (1996)
    Springer
    Journal of hepato-biliary-pancreatic surgery 3 (1996), S. 133-141 
    Details
    ISSN: 1436-0691
    Keywords: inflammatory pseudotumor ; liver ; computed tomography ; magnetic resonance imaging ; radiology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To determine the characteristic radiologic findings of inflammatory pseudotumor of the liver, various imagings of ten patients (11 lesions) with proven diagnoses of inflammatory pseudotumor were reviewed. Radiologic examinations, i.e., computed tomography (CT; 11 lesions), ultrasonography (11 lesions), magnetic resonance imaging (MRI; 6 lesions), angiography (10 lesions), CT during arterio-portography (CTAP; 3 lesions), and gallium-67 scans (9 lesions) were analyzed for their utility in diagnosis. No inflammatory pseudotumor showed a fibrous capsule around the lesion. Ten of the 11 lesions were poorly demarcated on most of the imagings, and all 11 lesions showed delayed and/or prolonged enhancement on CT or MRI. Arterio-portal shunting was observed in 4 lesions after contrast material administration on CT or angiography. Central lesions with suspiciously high fibrotic tissue content were demonstrated in 5 lesions on CT or MRI. Major vessels coursing in the lesions were demonstrated in 4 lesions by CT, MRI, and CTAP. Inflammatory pseudotumor of the liver should be included in the differential diagnosis in patients with hepatic masses, even if the patients are asymptomatic. If radiologic examinations suggest inflammatory pseudotumor, percutaneous biopsies should be performed so that unnecessary surgery can be avoided.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02350922
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  • 3
    Electronic Resource
    Electronic Resource
    Acute suppurative perithyroiditis: MR findings (1997)
    Springer
    Pediatric radiology 27 (1997), S. 353-355 
    Details
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report the MR findings in two cases of acute suppurative perithyroiditis. MR has the advantages over other imaging modalities of being able to distinguish areas of inflammation from adjacent normal tissue and of allowing imaging in planes which more accurately demonstrate the extent of the lesion. MR imaging is one of the most useful methods to evaluate this entity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002470050150
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  • 4
    Electronic Resource
    Electronic Resource
    Phase II study of a new combined primary chemotherapy regimen, intravenous methotrexate and vincristine and intraarterial Adriamycin and cisplatin, for locally advanced urinary bladder cancer: preliminary results (1995)
    Springer
    Cancer chemotherapy and pharmacology 35 (1995), S. 357-363 
    Details
    ISSN: 1432-0843
    Keywords: Key words Urinary bladder cancer ; Intraarterial infusion ; Cisplatin ; Adriamycin ; Angiotensin II ; Interventional procedures
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  A phase II study of a new combination therapy was performed using intraarterial (i.a.) cisplatin and Adriamycin in combination with i.v. methotrexate and vincristine for 27 patients with invasive urinary bladder carcinoma of stages T2–3NOMO, and the therapeutic effects were assessed. Methotrexate (20 mg/ m2) was given i.v. on days 1,15, and 22, and vincristine (0.7 mg/m2) was injected i.v. on day 2 before i.a. infusion therapy and on days 15 and 22. The i.a. chemotherapy was performed after both superior gluteal arteries had been embolized using 3- or 5-mm stainless-steel coils. A mixture of cisplatin (50– 70 mg/m2) and Adriamycin (20 mg/m2) was infused i.a. via both internal iliac arteries over a period of 20–30 min. Angiotensin II (mean dose, 21 μg) was simultaneously infused i.a. in 15 of 27 patients. In 24 of the 27 patients, at least 2 cycles of full-dose chemotherapy were completed. The dose was decreased in the remaining 3 patients because of their poor health status and advanced age. Among the 27 patients, 9 and 14 had complete (CR) and partial responses (PR), respectively; 3 manifested no change (NC), and 1 had progressive disease (PD). The objective response rate (CR+PR) was 85.2%. Among the 27 patients staged T2–3 NOMO, 6 (CR, 1; PR, 5) underwent total cystectomies and 18 (CR, 8; PR, 8; NC, 2) had transurethral resection of a bladder tumor (TUR-Bt) or partial resections following chemotherapy. The remaining 3 diminished-dose patients had no surgery. Of the 27 patients, 22 were alive after a median follow-up period of 21+ (range, 7–48+) months. No significant side effect was observed except for lower extremity paresthesias in 5 patients (18.5%). These results point to the effectiveness of this therapy and to the possibility of urinary bladder preservation in patients with invasive, advanced urinary bladder cancers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002800050247
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  • 5
    Electronic Resource
    Electronic Resource
    Coil Embolization of Arterioportal Fistula That Developed After Partial Gastrectomy (1999)
    Springer
    CardioVascular & interventional radiology 22 (1999), S. 328-330 
    Details
    ISSN: 1432-086X
    Keywords: Key words: Extrahepatic arterioportal fistula—Gastrectomy—Embolization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 51-year-old man suffered from bleeding esophageal varices. He had undergone partial gastrectomy for gastric cancer 1 year before. An extrahepatic arterioportal fistula and resultant portal hypertension were found. We successfully performed transarterial embolization of the fistula using stainless steel coils. Portal hypertension improved dramatically. RID="" ID="" 〈E5〉Correspondence to:〈/E5〉 K. Ishigami, M.D.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00012247
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  • 6
    Electronic Resource
    Electronic Resource
    Cerebellar vascular response to acetazolamide in crossed cerebellar diaschisis: a comparison of99mTc-HMPAO single-photon emission tomography with15O-H2O positron emission tomography (1996)
    Springer
    European journal of nuclear medicine 23 (1996), S. 683-689 
    Details
    ISSN: 1619-7089
    Keywords: Crossed cerebellar diaschisis ; Acetazolamide ; Technetium-99m hexamethylpropylene amine oxime ; Cerebral blood flow ; Emission computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Various observations on the cerebellar vasoreactivity in crossed cerebellar diaschisis (CCD) have previously been reported. The purpose of this study is to clarify the difference between oxygen-15 H2O positon emission tomographic (PET) and technetium-99m hexamethylpropylene amine oxime (HMPAO) single-photon emission tomograph (SPET) findings in CCD and to evaluate the effect of the absolute values of the cerebellar blood flow as measured by15O-H2O PET on the99mTc-HMPAO SPET findings. The subjects comprised 15 patients with a supratentorial infarct and CCD. The cerebellar blood flow increased by about 40% at 5 and 20 min after acetazolamide i.v. on both the CCD and the non-CCD side, as measured by 150-1120 PET. The percentage differences in cerebellar blood flow between the CCD and the non-CCD side were −22.3%±5.7% in the resting state, −19.6%±6.4% at 5 min after acetazolamide i.v. and 21.5%±6.7% at 20 min after acetazolamide i.v., as measured by15O-H2O PET, while they were −10.6%±5.5% in the resting state and −5.6%±5.1% at 5 min after acetazolamide i.v., as measured by99mTc-HMPAO SPET. After Lassen's linearization correction, the latter two measurements were −16.2%±7.7% and −9.6%±8.9%, respectively. The effect of acetazolamide did not differ between the CCD and the non-CCD side in15O–H2O PET, while a greater response on the CCD side was observed in99mTc-HMPAO SPET, even after Lassen's linearization correction. It is concluded that acetazolamide HMPAO SPET may overestimate the cerebellar vascular response on the CCD side (or underestimate it on the non-CCD side).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00834531
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  • 7
    Electronic Resource
    Electronic Resource
    A comparative study of thallium-201 SPET, carbon-11 methionine PET and fluorine-18 fluorodeoxyglucose PET for the differentiation of astrocytic tumours (1998)
    Springer
    European journal of nuclear medicine 25 (1998), S. 1261-1269 
    Details
    ISSN: 1619-7089
    Keywords: Key words: Brain tumours ; Thallium chloride ; Carbon-11 methionine ; Fluorine-18 fluorodeoxyglucose ; Single-photon emission tomography ; Positron emission tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Thallium-201, carbon-11 methionine (MET) and fluorine-18 fluorodeoxyglucose (FDG) have all been used to assess brain tumours. The aim of this study was to determine which of these tracers are of use for evaluating the histological grade and the extent of astrocytoma. 201Tl single-photon emission tomography (SPET), MET positron emission tomography (PET) and FDG PET were all performed in 23 patients (13 men, 10 women) with newly diagnosed astrocytic tumours [seven with astrocytoma (grade II), ten with anaplastic astrocytoma (grade III) and six with glioblastoma (grade IV)]. The 201Tl uptake of the tumours was evaluated by a lesion-to-normal region count ratio. Both MET and FDG uptake of the tumours was evaluated by a semiquantitative analysis using the standardized uptake value. 201Tl uptake was found to increase in rank order with histological grade and was significantly different among the three groups (grade II: 1.51±0.36; grade III: 2.58±1.50; grade IV: 7.65±3.84). MET uptake in grade II (1.49±0.44) was also significantly lower than that in both grade III (3.29±1.44) and grade IV (3.20±0.92). FDG uptake was not significantly different among the three groups (grade II: 2.90±0.45; grade III: 3.86±1.56; grade IV: 3.57±0.83). No significant correlation was observed between 201Tl uptake and either MET uptake or FDG uptake. In most patients, the extent of the increased MET uptake was the largest while that of the increased FDG uptake was the smallest. In patients with positive 201Tl uptake, the extent of the 201Tl uptake was equal to or smaller than that of gadolinium enhancement. For evaluation of histological grade of astrocytic tumours. 201Tl is therefore considered to be useful though the 201Tl uptake in some grade III astrocytomas was not different from that in grade II astrocytomas. MET was found to be highly useful for detecting astrocytomas, for differentiating between benign and malignant astrocytomas, and for evaluating the extent of astrocytomas; however, it was not sufficiently useful permit evaluation of the histological grade. FDG was not found to be useful either for evaluating the histological grade or for differentiating between benign and malignant astrocytomas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002590050294
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  • 8
    Electronic Resource
    Electronic Resource
    The usefulness of FDG positron emission tomography for the detection of mediastinal lymph node metastases in patients with non-small cell lung cancer: a comparative study with X-ray computed tomography (1996)
    Springer
    European journal of nuclear medicine 23 (1996), S. 741-747 
    Details
    ISSN: 1619-7089
    Keywords: Lung cancer ; Mediastinal lymph node ; Fluorine-18-fluoro-2-deoxy-d-glucose ; Positron emission tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We evaluated the usefulness of fluorine-18-fluoro-2-deoxy-d-glucose positron emission tomography (FDG PET) in the detection of mediastinal lymph node metastases in patients with non-small cell lung cancer and then compared the findings with the results of X-ray CT by region based on the histological diagnoses. We examined 29 patients with non-small cell lung cancer. One hundred and thirty-two mediastinal lymph nodes were surgically removed and the histological diagnoses were confirmed. FDG PET images, including 146 mediastinal regions, were visually analysed and the mediastinal lymph nodes were scored as positive when the FDG uptake was higher than that in the other mediastinal structures. On the X-ray CT scans, any mediastinal lymph nodes with a diameter of 10 mm or larger were scored as positive. All three examinations were successfully performed on 71 regions. For FDG PET, we found a sensitivity of 76%, a specificity of 98% and an accuracy of 93%. On the other hand, for X-ray CT a sensitivity of 65%, a specificity of 87% and an accuracy of 82% were observed. A significant difference was observed in respect of both specificity and accuracy (P〈0.05). Based on the above findings, FDG PET is suggested to be superior to X-ray CT when used for the detection of mediastinal lymph node metastases in patients with non-small cell lung cancer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00843701
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  • 9
    Electronic Resource
    Electronic Resource
    Human middle latency auditory evoked magnetic fields (1996)
    Springer
    Brain topography 8 (1996), S. 291-296 
    Details
    ISSN: 1573-6792
    Keywords: Middle latency auditory evoked magnetic fields ; MLR ; AEFs ; MEG ; Human brain ; SQUID
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The magnetic equivalents of SN10, Po, Na, Pa, Nb and Pb (SN10m, Pom, Nam, Pam, Nbm and Pbm) in short and middle latency auditory evoked potentials were measured with a 7-channel DC superconducting quantum interference device (SQUID). The sources of Pom, Nam, Pam, Nbm and Pbm responses were estimated to be located in the auditory cortex, while the source of SN10m was considered to be in a deeper part of the brain. In addition, the source of Pam was estimated to be in the vicinity of the moving N100m source. The source of Pbm was considered to be in a separate area, anterior to the source of Pam and N100m, which suggested that the source of Pam was located in the primary auditory cortex, while the source of Pbm was located in the secondary auditory cortex. The source of N100m was considered to spread from the primary auditory cortex to the secondary auditory cortex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01184787
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