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  • 11
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 12
    ISSN: 1432-1238
    Keywords: Subcutaneous oxygens tension ; Transcutaneous oxygen tension ; Tissue perfusion ; PEEP ; Cardiac output ; Oxygen delivery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective To compare subcutaneous (PscO2) and transcutaneous (PtcO2) oxygen tension measurements in relation to hemodynamic variables at different levels of PEEP, and to evaluate the usefulness of these measurements as monitors of peripheral tissue perfusion. Design Prospective trial. Setting Intensive care unit in a university hospital. Patients Seven patients with gastric cancer who where undergoing total gastrectomy. Interventions Silicone catheter was placed in the upper arm and transcutaneous oxygen monitor was placed on the upper part of the chest. A pulmonary artery catheter was placed in the right pulmonary artery. Measurements and results PscO2 and PtcO2 together with hemodynamic variables were measured at different levels of PEEP. Progressive increase of PEEP reduced cardiac index (CI) (p〈0.05) with a concomitant decrease of PscO2 (p〈0.05) and oxygen delivery (DO2) (p〈0.05). Changes in PtcO2 parallelled changes in arterial oxygen tension (PaO2), but no correlation was found between PtcO2, CI and DO2. Conclusion PscO2 is a sensitive indicator of subcutaneous tissue perfusion, which can be used to identify the PEEP level, with optimum peripheral perfusion. PscO2 seems to be a more reliable indicafor of tissue perfusion than PtcO2.
    Type of Medium: Electronic Resource
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  • 13
    Electronic Resource
    Electronic Resource
    Springer
    Combinatorica 12 (1992), S. 27-37 
    ISSN: 1439-6912
    Keywords: 52 A 25 ; 90 C 10
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract We give an upper bound on the number of vertices ofP I , the integer hull of a polyhedronP, in terms of the dimensionn of the space, the numberm of inequalities required to describeP, and the size ϕ of these inequalities. For fixedn the bound isO(m n ϕ n− ). We also describe an algorithm which determines the number of integer points in a polyhedron to within a multiplicative factor of 1+ε in time polynomial inm, ϕ and 1/ε when the dimensionn is fixed.
    Type of Medium: Electronic Resource
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  • 14
    Electronic Resource
    Electronic Resource
    Springer
    Molecular biology reports 10 (1985), S. 153-158 
    ISSN: 1573-4978
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Complexes of histone H1 from sea urchin sperm (H1S) and calf thymus (H1T) with superhelical DNA I and relaxed circular DNA II have been analyzed by analytical sedimentation. Similar to H1T, the highly basic and relatively arginine-rich histone H1S preferentially interacts with DNA I compared to DNA II under competition conditions. However, H1S induces a stronger aggregation of bothforms of DNA than H1T. Below 0.05 M NaCl, the soluble complexes formed by both histones have similar properties, but aggregation proceeds in a different manner: H1S induces a stronger aggregation of DNA II as compared to DNA I, whereas H1T fails to aggregate DNA I. The results are explained on the basis of differences in amino acid sequence and structure of the two histones and related to the special chromatin condensing ability of histone H1S.
    Type of Medium: Electronic Resource
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  • 15
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Low-temperature scanning electron microscopy has been performed for imaging the spatial distribution of the critical current densityj c(x,y) and of the critical temperatureT c(x,y) in polycrystalline superconducting YBaCuO films. Strongly inhomogeneous behavior has been observed, and the spatial resolution limit has been found to be 1–2 μm. The local temperature increment in the specimen film caused by the electron beam scanning has been demonstrated experimentally as the underlying mechanism of the imaging principle, and the beam-induced thermal perturbation of the high-T c film/substrate configuration is discussed in detail. The radiation hardness of the sample films against the electron beam irradiation in our imaging experiments has been evaluated. No radiation damage could be detected up to the maximum applied dose of well above 1020 electrons/cm2 for a typical beam energy of 26 keV.
    Type of Medium: Electronic Resource
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  • 16
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 28 (1993), S. 321-329 
    ISSN: 1434-6079
    Keywords: 36.40. + d ; 32.80.Wr ; 33.80.Gj
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Na clusters bound to mica surfaces have been irradiated with pulsed and cw visible laser light. Kinetic energy and angular distributions of the Na atoms desorbing from the clusters have been determined using cw two-photon laser-induced fluorescence detection. In addition the dependence of the desorption rate on laser power, wavelength and polarization has been measured. The most probable kinetic energyE kin of the photodesorbed atoms at the surface temperatureT S =300 K was found to beE kin=18±5 meV, independent of laser irradiance (3 µJ/cm2...20 mJ/cm2) and wavelength (450 nm, 505 nm, 658 nm). With increasing orientation angle between detection axis and surface normal (0°≦Θ≦90°)E kin was observed to decrease slightly, while it was nearly independent of surface temperature betweenT S =30 K andT S =300 K. Also, with increasing radius of the Na clusters the desorbing Na atoms slowed down. The angular distribution of the Na atoms was of cos2-type with respect to the surface normal. These observations suggest that laser-induced desorption of Na from Na clusters bound to mica surfaces involves an initial rate-limiting step of direct surface plasmon excitation followed by a final step of delayed thermal desorption.
    Type of Medium: Electronic Resource
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  • 17
    ISSN: 1437-3262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Abstract Manganese nodules from the Kane Gap (a deep sea channel connecting the Sierra Leone and Gambia Basins off West Africa) were investigated chemically and dated by10Be along cross-sections. Comparing the nodule structure with the stratigraphy of the related sediments, the following conclusions are drawn concerning the sedimentation processes during the last 4 to 6×106 years: The growth of the nodules started about 4 to 4.5 Ma before present during or near to the end of a period of erosion on a fossil-free, probably Miocene sediment. During the first phase of only a few hundred thousandyears, the nodules grew very quickly (7 to 〉18 mm/Ma). Fe-rich hydrogenetic material formed the internal sections of the nodules during this time. Slowing down of the bottom currents, resulting in deposition of thin sediment covers for short intervals, caused the character of the nodules to change to a more diagenetic composition. The growth rates were reduced to about 1 to 2 mm/Ma. The time of slowing is roughly 3 to 4 Ma BP. Probable uncertainties of the dating and growth rates resulting from supposed changes of the10Be supply to the nodules due to variations of the near bottom environment are discussed.
    Abstract: Résumé Le «Kana Gap» est un chenal sous-marin qui relie les bassins de Sierra Leone et de Gambie, au large de l'Afrique occidentale. Des nodules de manganèse, recueillis le long de profils transversaux dans ce chenal, ont fait l'objet d'une étude chimique et d'une détermination d'âge10Be. La comparaison entre la structure des nodules et la stratigraphie des sédiments sous-jacents permet de tirer les conclusions suivantes relatives au processus sédimentaire au cours des 4 à 6 derniers Ma. La croissance des nodules a commencé il y a environ 4 à 4,5 Ma pendant ou juste après un épisode d'érosion sous-marine sur des sédiments non fossilifères, probablement miocènes. Au cours d'une première phase d'une durée de quelques centaines de milliers d'années, la croissance a été très rapide (7 à 〉 18 mm par Ma) avec formation de la partie centrale du nodule, constituée de matière hydrogénée riche en Fe. Ensuite, après ralentissement des courants de fond et dépôt probable d'une mince couche de sédiment, le caractère des nodules a évolué vers une composition plus diagénétique, avec réduction du taux de croissance à 1 à 2 mm par Ma. Le moment de ce changement de régime doit se situer entre 3 et 4 Ma. Des changements dans les conditions de milieu sur le fond de la mer pourraient avoir provoqué une variation de la quantité de10Be apportée aux nodules, d'où résulterait une incertitude sur l'estimation des âges et du taux de croissance; cette question est discutée par les auteurs.
    Notes: Zusammenfassung An Manganknollen aus der Kane-Lücke, dem Verbindungskanal zwischen Sierra Leone Becken und Gambia Becken (vor W-Afrika) wurden entlang Querprofilen durch mehrere Knollen chemische Untersuchungen und10Be Altersbestimmungen durchgeführt. Durch Vergleich des Aufbaus der Knollen mit der Stratigraphie des unterlagernden Sediments werden Rückschlüsse auf Veränderungen des Sedimentationsgeschehens während der letzten 4–6×106 Jahre gezogen. Hiernach begann das Wachstum der Knollen vor maximal 4.5×106 Jahren während oder gegen Ende einer Erosionsphase auf fossilfreiem, vermutlich miozänem Sediment. Während der ersten Phase wuchsen die Knollen über wenige 100000 Jahre sehr schnell (7 bis〉18 mm/106 Jahre). Hierbei schied sich Fe-reiche Knollensubstanz hydrogener Zusammensetzung ab. Nach Verringerung der Strömung und vermutlich zeitweiser Bildung von dünnen Sedimentschleiern änderte sich der Charakter der Knollen zu mehr diagnetischer Zusammensetzung bei wesentlich reduziertem Wachstum (ca. 1 bis 2 mm/106 Jahre). Der Zeitpunkt der Umstellung ist nur sehr grob zu ermitteln, er dürfte etwa zwischen 3 und 4×106 Jahren vor heute liegen. Eventuelle Unsicherheiten bei der Datierung und den Wachstumsraten, die möglicherweise aus milieubedingten Änderungen in der10Be Versorgung der Knollen resultieren, werden diskutiert.
    Type of Medium: Electronic Resource
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  • 18
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 328 (1986), S. 545-545 
    ISSN: 0021-8383
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 19
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 329 (1987), S. 433-438 
    ISSN: 0021-8383
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Synthesis and Polymerization of Unsaturated BenzaldazinesThe preparation of methacrylic and acrylic acid derivatives of isomeric hydroxybenzaldazines and their characterization by u.v.-, i.r.-, 1H and 13C n.m.r. spectroscopy are described. By radical polymerization and copolymerisation with styrene and methyl methacrylate, respectively, crosslinked polymers showing ultraviolet-absorbing properties are obtained.
    Additional Material: 5 Tab.
    Type of Medium: Electronic Resource
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  • 20
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The binding of iodinated basic fibroblast growth factor (bFGF) to low-density heparan sulfate proteoglycan purified from the Engelbreth Holm Swarm (EHS) sarcoma was investigated using different techniques. The tumor clearly contained bFGF, the level being comparable to that found in other tissues such as human or bovine brain. 125I bFGF strongly bound to the basement membrane-like matrix of EHS frozen sections as revealed by autoradiography. Iodinated bFGF bound to purified heparan sulfate proteoglycan but not to laminin or collagen type IV, three components isolated from the same tumor. In contrast, acidic fibroblast growth factor (aFGF) displayed negligible binding to heparan sulfate proteoglycan. Binding of bFGF to frozen sections and to purified proteoglycan could be strongly inhibited by heparin and was displaced by an excess of unlabeled factor and completely suppressed after heparitinase and heparinase treatments. Binding was a function of the salt concentration and was abolished at 0.6 M NaCl. Scatchard analysis indicated the affinity site had a Kd of about 30 nM, a value 10-15 higher than that recently reported by Moscatelli (J. Cell. Physiol., 131:123-130, 1987) in the case of the low-affinity binding sites present on the surface of baby hamster kidney (BHK) cells.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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