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  • 1990-1994  (2)
  • 1985-1989  (1)
  • 25.70.-z  (1)
  • Chemistry  (1)
  • side-effects  (1)
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  • 1990-1994  (2)
  • 1985-1989  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 28 (1985), S. 135-138 
    ISSN: 1432-1041
    Keywords: hypertension ; cadralazine ; vasodilators ; chlorthalidone ; atenolol ; side-effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The antihypertensive efficacy of a new long-lasting vasodilator, cadralazine, and the diuretic chlorthalidone have been compared in hypertensive patients receiving concurrent treatment with atenolol. After a 4-week run-in period with atenolol alone 100 mg/day, two groups of 10 patients whose diastolic blood pressure exceeded 100 mm Hg were given for a period of 65 days either cadralazine 15 mg/day or chlorthalidone 25 mg/day, according to a randomized, double-blind, between-patients design. Compared to atenolol alone, both cadralazine and chlorthalidone induced a statistically and clinically significant decrease in blood pressure. The antihypertensive effect did not differ significantly between groups. Good compensation of the atenolol-induced decrease in heart rate was obtained with cadralazine, whereas during atenolol + chlorthalidone treatment at times the standing heart rate was significantly lower than during treatment with atenolol + cadralazine. Side-effects, many of which were already present during atenolol treatment, occurred with a similar frequency in both groups. It is concluded that atenolol + cadralazine and atenolol + chlorthalidone are equally well tolerated, acceptable and effective in the treatment of hypertension, but that further studies are warranted to explore the potential haemodynamic advantages of the cadralazine + atenolol combination.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-601X
    Keywords: 25.70.-z
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The28Si+64Ni reaction at 163.8 MeV incident energy is studied by measuring in coincidenceγ-rays and charged particles identified from Z=2 to Z=16. The transition from quasi-elastic to more damped reactions is observed when the difference between the detected charge and the projectile one is increased. The strong influence of the particle decay on the measuredγ-ray multiplicity is evidenced with the help of the statistical model computer code CASCADE. Dissipative events are well described in the rolling limit with excitation energy equally shared between the fragments. The overall agreement is lost for the fragments with the projectile charge which show a small value of theγ-multiplicity even for dissipative events. This is probably connected with the previously observed non statistical behavior of gamma rays emitted in coincidence with projectile-like fragments. In the alpha-spectrum measured in coincidence with gamma-rays, the deexcitation of fused systems is clearly separated from in flight emission of deep inelastic fragments. The low measured gamma-ray multiplicity for fusion events is qualitatively explained taking into account the effect of alpha-emission in the statistical decay.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Acta Polymerica 43 (1992), S. 327-330 
    ISSN: 0323-7648
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: Die physikalischen Eigenschaften von Polymercompositen, die durch Mischung des kristallinen, bioabbaubaren und bioverträglichen Polymers Poly-D( - )(3-hydroxybutyrat) (PHB) mit nichtkristallinem, ataktischen Poly(epichlorhydrin) (PECH) erhalten wurden, werden untersucht. Die durch Eindampfen von Lösungen hergestellten PHB/PECH-Mischungen wurden mit Hilfe von thermomechanischen, röntgenographischen und viskolastischen Messungen sowie durch ihr Festigkeits- und Dehnungsverhalten charakterisiert. Aus den Ergebnissen wurde geschlossen, daß die kristallinen Bereiche des PHB die Rolle von Vernetzungen spielen, während das zwischen den kristallinen Bereichen befindliche amorphe PECH als Weichmacher wirkt. Ein einfacher dynamischer Verlustmodul, der der Glasübergangstemperatur entspricht, weist auf die Mischbarkeit des kristallinen PHB mit dem amorphen PECH hin.
    Notes: Physical properties of a new polymer blend obtained by mixing poly-D( - )(3-hydroxybutyrate) (PHB), a crystalline polymer with interesting properties of biodegradability and biocompatibility, with uncrystallizable atactic poly(epichlorohydrin) (PECH) were studied. PHB/PECH blends, obtained by casting solution, were analysed by thermomechanical and X-ray analysis, viscoelastic measurements, and on the basis of strength and elongation measurements. It was concluded that the crystalline region of PHB plays an important role of crosslinks, and amorphous PECH filled between the crystalline regions plays a role of plasticizer. A single dynamic loss modulus, corresponding to the glass transition temperature, implies the miscibility between crystalline PHB and amorphous PECH.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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