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  • 1
    ISSN: 1476-5535
    Keywords: Antifungal ; Sch 40873 ; Candida albicans ; Mycelial
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Sch 40873, a novel antifungal compound isolated from the fermentation broth of anActinomadura spp. was discovered in an assay designed to detect compounds with preferential activity against the invasive mycelial form ofCandida albicans. The geometric mean MIC of Sch 40873 against sevenCandida spp. in Sabouraud dextrose broth (yeast phase) was ≥58 μg/ml and in Eagles minimum essential medium (mycelial phase) was 〈0.03 μg/ml. Sch 40873 demonstrated slight in vivo topical activity in a hamster vaginal model.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Colloid & polymer science 265 (1987), S. 592-596 
    ISSN: 1435-1536
    Keywords: Morphology ; crystallization ; singlecrystal ; trans-1 ; 4-polyisoprene
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The film formation method has been successfully used to grow single crystals and other complex morphological features of low melting form (LMF) and high melting form (HMF) of trans-1,4-polyisoprene (TPIP). Below 40 °C dilute amyl acetate solution gave hexagonal shaped LMF crystals. Thick and elongated hexagonal shaped morphology was shown by HMF crystals at temperatures above 40 °C. Straight faces and sharp corners of the single crystals, and also of complex crystals, acquired round shapes when highly polydispersed TPIP was used for crystallization.
    Type of Medium: Electronic Resource
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