ISSN:
1572-8854
Source:
Springer Online Journal Archives 1860-2000
Topics:
Geosciences
,
Physics
Notes:
Abstract The title compound, l-(2,3-dideoxy-3-azido-β-D-erythro pentofuranos-1-yl)-5-chlorocytosine, crystallizes in the orthorhombic space groupP212121 witha=5.840(1),b=13.780(1),c=15.396(2)Å,Z=4. The structure was solved by direct methods and refined by full-matrix least-squares calculations to a finalR value of 0.033 for 1688 unique observed reflections. The N-glycosidic torsion angle χ has a value of −160.8(1)°, in the and range. The sugar pucker is 2 3 T withP=180(1)° andψ=34(1)°. The C4′–C5′ conformation is +sc with γ=50.8(2)°. The azido group is nonlinear and oriented trans to the C3′–C4′ bond. The molecular packing in the crystalline space is stabilized by N-H⋯N, N-H⋯O, O-H⋯O hydrogen bonds and C-H⋯O close contacts.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01159148
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