Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    The inhibitory effect of X537A on vascular and intestinal smooth muscle contraction (1984)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 325 (1984), S. 80-84 
    Details
    ISSN: 1432-1912
    Keywords: X537A ; Smooth muscle contractions ; Rabbit aorta ; Guinea-pig Taenia coli ; Metabolic inhibition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary the effects of X537A (Lasalocid) on contractions induced in vascular and intestinal smooth muscles were examined. High K-induced sustained contractions were inhibited by X537A with an IC50 of 2.8·10−6 M in rabbit aorta and 8.8·10−8 M in guinea-pig Taenia coli. Changing the Ca concentration in the medium did not modify the effect of X537A. X537A also inhibited the noradrenaline-induced contraction in aorta (IC50=7.0·10−8 M). In a solution without added glucose, the inhibitory effect of X537A on the K-induced contraction in aorta was augmented (IC50=1.5·10−8 M). Under hypoxic conditions, the inhibitory effects of X537A on the noradrenaline-induced contractions in aorta and on the K-induced contraction in T. coli were decreased (IC50〉10−5 M and 3.2·10−6 M, respectively). X537A inhibited the K-induced increase in cellular 45Ca content in aorta measured by a modified lanthanum method. However, the IC50 for 45Ca uptake (6.6·10−7 M) was lower than that for K-induced contraction. In both tissues, X537A decreased the ATP content. Oxygen consumption of rat liver mitochondria was inhibited by X537A. From these results, it is concluded that the inhibitory effect of X537A on the noradrenaline-induced contraction in aorta and the K-induced contraction in T. coli, but not the K-induced contractions in aorta, may be due to the inhibition of aerobic metabolism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00507058
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    CPS GL 799 (1991)
    Springer
    Colloid & polymer science 269 (1991), S. 70-76 
    Details
    ISSN: 1435-1536
    Keywords: Illuminationeffect ; adsorption ; diffusion ; cellulosemembrane ; directdye
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The effect of illumination on transport of sulfonated bisazo direct dyes, CI Direct Yellow 12, and CI Direct Yellow 4, into a cellulose membrane has been studied at various temperatures. Transport of CI Direct Yellow 12, which exhibits photoinduced reversible trans-cis isomerism in aqueous solution into a cellulose membrane, was influenced by illumination. It is likely that the transport was influenced by transisomerization of the photoisomeric dye and the diffusivity was controlled by surface diffusion rather than by pore diffusion under both light and dark conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00654661
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...