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  • 1
    Electronic Resource
    Electronic Resource
    Melanocytic lesions in lymph nodes associated with congenital naevus (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 23 (1993), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Two cases of melanocytic lesions in lymph node associated with congenital naevus are presented. The first was a 30-year-old man with a nodular melanoma arising in a small congenital naevus. The second was a 2-year-old male infant with a giant congenital naevus. In both cases, naevus cell aggregates were observed in the capsule, trabeculae, perisinusoidal areas and lymphatic vessels surrounding the nodes. In the first case, clusters of large atypical melanocytes were present amongst naevus cell aggregates in the perisinusoidal areas as well as in the lymphoid parenchyma. Between the naevus cells and large atypical melanocytes, transitional forms were observed which supports the idea that the presence of large atypical melanocytes is indicative of benign naevus cells. In the second case, marginal sinuses were packed with clusters of large melanin-rich cells. Immunohistochemically, these cells were S-100 protein negative, but ultrastructural studies proved them to be melanocytes. They were considered indicative of spread of benign naevus cells via lymphatic vessels. Arrested migration of naevus cells during embryogenesis and benign spread of naevus cells are possible explanations for the histogenesis of naevus cell aggregates in lymph nodes associated with congenital naevus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.1993.tb00493.x
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  • 2
    Electronic Resource
    Electronic Resource
    Differential expression of CR3, FcɛRll and FcγRlll on Polymorphonuclear leukocytes in gingival crevicular fluid (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 28 (1993), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Polymorphonuclear leukocytes (PMNLs) are the most numerous cell population among the cellular infiltrates in gingival crevicular fluid (GCF) and play important roles in the host-defensive system in the gingival crevices. We determined the percentage of neutrophils, cosinophils and basophils in total PMNLs by light microscopic observation using Randolph-methylene blue staining, then assessed flow cytometric differences in the expression of CR3, FcγRIII, FcɛRII. LFA-1α, and LFA-Iβ on PMNL in GCF and peripheral blood (PB) from 21 patients with adult periodontius (AP) and 13 healthy donors. Percentages of basophils and eosinophils were higher in GCF than in PB. In both AP patients and healthy subjects, expression of CR3 and FcɛRll was higher while FeγRIII was lower in GCF than in PB. The statistical analysis showed that the expressions of FcγRIII and FcɛRII on GCF PMNLs were lower in AP patients than in healthy subjects. Expressions of LFA-1α and β on GCF were similar to those on PB PMNLs. PB PMNLs stimulated in vitro with Porphyromonas gingivalts culture supernatant and fMLP displayed an expression pattern of CR3, FcγRIII and FcɛRII on GCF PMNLs. However, C5a and IL-I failed to induce changes in FcγRIII and FcɛRII. The results indicate that GCF neutrophils are activated, present enhanced adhesion and a decreased IgG-binding ability which would reflect that they are at the terminal stage of activation, and that GCF contains a larger eosinophil fraction than in PB. Moreover, these GCF eosinophils appear to be activated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1993.tb01080.x
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  • 3
    Electronic Resource
    Electronic Resource
    Duration patterns of percussion sound in healthy and periodontally affected teeth (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 17 (1990), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Ten periodontally affected subjects and 10 healthy subjects were selected in order to examine the duration patterns of percussion sounds in all upper teeth, excluding the 8′s.Probing depth, loss of attachment, tooth mobility by ‘Periotest’, bone loss and percussion sound duration via occlusal sound analyser were recorded during the pretreatment period.The following results were obtained from the study:〈list xml:id="l1" style="custom"〉(i)the normal duration of percussion sounds ranged from 4.40–5.33 ms;(ii)percussion sound values of periodontal patients were of longer duration than those of healthy subjects;(iii)a close correlation between duration and other individual parameters was found in all upper teeth, with the exception of molars.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2842.1990.tb01429.x
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  • 4
    Electronic Resource
    Electronic Resource
    A simple, rapid and simultaneous analysis of complex volatile hydrocarbon mixtures in blood using gas chromatography/mass spectrometry with a wide-bore capillary column (1990)
    Springer
    International journal of legal medicine 103 (1990), S. 567-572 
    Details
    ISSN: 1437-1596
    Keywords: Volatile hydrocarbons in the blood ; screening method ; flüchtige Kohlenwasserstoffe im Blut ; Screeningmethode
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Es wird über eine Screeningmethode zum Nachweis flüchtiger Kohlenwasserstoffe im Blut mittels Gaschromatographie/Massenspektrometrie berichtet, wobei wide-bore Kapillaren und die Headspace-technik eingesetzt wurden. Toluol-d8 und Indan dienten als interne Standards bei der quantitativen Analyse. Kohlenwasserstoffe mit Retentionsindizes zwischen 600 und 1200 konnten mit der Ionenchromatographie simultan und quantitativ noch in relativ geringen Konzentrationsbereichen bis 0.01 μg/ ml bestimmt werden. In der Praxis ist die Methode nützlich, wenn es in forensischen Fällen darum geht, komplexe Kohlenwasserstoffgemische (wie z. B. Petroleum) rasch zu analysieren.
    Notes: Summary A screening method for detecting volatile hydrocarbons in blood has been developed using gas chromatography/mass spectrometry with a wide-bore capillary column and a headspace method. Toluene-d8 and indan were used as the internal standards for quantitative analysis. Hydrocarbons with retention indices from 600 to 1200 were simultaneously and quantitatively detected in relatively low concentrations (0.01 μg/m1) in reconstructed ion chromatography. This method could prove useful in forensic cases in which urgent examination of complex hydrocarbon mixtures, e.g. petroleum components, is required.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00202716
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  • 5
    Electronic Resource
    Electronic Resource
    A simple, rapid and simultaneous analysis of complex volatile hydrocarbon mixtures in blood using gas chromatography/mass spectrometry with a wide-bore capillary column (1990)
    Springer
    International journal of legal medicine 103 (1990), S. 567-572 
    Details
    ISSN: 1437-1596
    Keywords: Volatile hydrocarbons in the blood ; screening method ; flüchtige Kohlenwasserstoffe im Blut ; Screeningmethode
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Es wird über eine Screeningmethode zum Nachweis flüchtiger Kohlenwasserstoffe im Blut mittels Gaschromatographie/Massen-spektrometrie berichtet, wobei wide-bore Kapillaren und die Headspace-technik eingesetzt wurden. Toluol-d8 und Indan dienten als interne Standards bei der quantitativen Analyse. Kohlenwasserstoffe mit Retentionsindi-zes zwischen 600 und 1200 konnten mit der Ionenchromatographie simultan und quantitativ noch in relativ geringen Konzentrationsbereichen bis 0.01 μg/ ml bestimmt werden. In der Praxis ist die Methode nützlich, wenn es in forensischen Fällen darum geht, komplexe Kohlenwasserstoffgemische (wie z.B. Petroleum) rasch zu analysieren.
    Notes: Summary A screening method for detecting volatile hydrocarbons in blood has been developed using gas chromatography/mass spectrometry with a wide-bore capillary column and a headspace method. Toluene-d8 and indan were used as the internal standards for quantitative analysis. Hydrocarbons with retention indices from 600 to 1200 were simultaneously and quantitatively detected in relatively low concentrations (0.01 μg/ml) in reconstructed ion chromatography. This method could prove useful in forensic cases in which urgent examination of complex hydrocarbon mixtures, e.g. petroleum components, is required.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01261420
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  • 6
    Electronic Resource
    Electronic Resource
    Postmortem changes in hapten-specific IgE antibody responses in mice (1991)
    Springer
    International journal of legal medicine 104 (1991), S. 133-135 
    Details
    ISSN: 1437-1596
    Keywords: Post-mortem change ; Immunoglobulin E ; Passive cutaneous anaphylaxis ; Viscera ; Mouse ; Postmortale Veränderungen ; Immunoglobulin E ; Passive kutane Anaphylaxie ; Organe ; Maus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Die Untersuchung wurde durchgeführt, um mit Hilfe des passiven kutanen Anaphylaxie-Tests bei Ratten die postmortale Stabilität des haptenspezifischen Immunoglobulins E von Mäusen zu überprüfen. In-vitro IgE-Antikörper-Antworten waren — unter Raumtemperatur-Bedingungen — 3 Tage unverändert. Selbst in Fällen, wo Blut vom Kadaver nicht gewonnen werden konnte, war es möglich, die hapten-spezifische IgE-Antikörper-Antwort bis zu 3 Tagen nach dem Tode zu bestimmen, indem der Überstand von Organ-Homogenaten verwendet wurde.
    Notes: Summary This Study was carried out to examine the post-mortem stability of hapten-specific immunoglobulin E (IgE) antibody in mice by the passive cutaneous anaphylaxis test in rats. In vitro IgE antibody responses in blood were stable for 3 days at room temperature. Even in cases when blood could not be obtained from the caver it was possible to measure the hapten-specific IgE antibody response up to 3 days after death using the supernatant of the visceral homogenates.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01369716
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  • 7
    Electronic Resource
    Electronic Resource
    A reinvestigation of the role of the grey crescent in axis formation in Xenopus laevis (1981)
    [s.l.] : Nature Publishing Group
    Nature 292 (1981), S. 511-516 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Gravitationally induced displacements of the contents of the frog egg can predictably determine the orientation of the subsequent dorsal–ventral axis of the embryo, regardless of the original position of sperm entry or of the grey crescent. In certain conditions, these displacements in the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/292511a0
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  • 8
    Electronic Resource
    Electronic Resource
    Infantile spasms: Etiological factors, clinical aspects, and long term prognosis in 200 cases (1981)
    Springer
    European journal of pediatrics 135 (1981), S. 239-244 
    Details
    ISSN: 1432-1076
    Keywords: Infantile spasms ; Etiological factors ; Clinical aspects ; Long term prognosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The etiological factors, clinical aspects and long term prognosis were studied in 200 patients with infantile spasms. Forty-eight (24.0%) died and the rest were aged 6 years or more at the time of final follow-up. In 73 (36.5%) the etiology was prenatal, in 44 (22.0%) perinatal, and in 17 (8.5%) postnatal: 18 cases (9.0%) were cryptogenic. The remaining 48 (24.0%) patients were doubtful cases. The mortality of the pre-and perinatal cases at 35.6% and 34.1% respectively was significantly higher than that in the other etiologic groups (P〈0.001). With regard to the onset of spasms, these were very carly in the pre-and perinatal groups, whereas in the postnatal group the onset was late. The onset in the doubtful and cryptogenic groups was in between. Some 44.4% of the cryptogenic cases showed normal mental and physical development after the age of 6 years, whereas less than 10% of the prenatal and perinatal group did so. Almost all of the doubtful cases became mentally subnormal. The incidence of a family history of epilepsy or other convulsive disorders in the first, second and third degree relatives was highest in the cryptogenic cases (40.0%), and lowest in the perinatal cases (9.3%) (P〈0.01). The incidence of laughing attacks was highest in the postnatal cases (42.9%), against no such attacks in cryptogenic cases (P〈0.01). The attacks seemed to be linked with organic brain lesions. Among various factors related to the etiology of infantile spasms, genetic propensity seemed especially important in cryptogenic cases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442097
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  • 9
    Electronic Resource
    Electronic Resource
    A model of the mechanisms of long-term potentiation in the hippocampus (1990)
    Springer
    Biological cybernetics 64 (1990), S. 33-39 
    Details
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Notes: Abstract Long-Term Potentiation (LTP) in the hippocampus has been considered to be a phenomenon closely related to learning and memory in the brain. In this paper, an integrated model of LTP is constructed based on hypotheses about both the mechanism of LTP induction and that of LTP maintenance, that is, the NMDA-receptor channel, protein phosphorylation and protein turnover. The validity of the model is discussed based on the results of computer simulations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00203628
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  • 10
    Electronic Resource
    Electronic Resource
    The value of EEG and cerebral evoked potentials in the assessment of neonatal intracranial hemorrhage (1981)
    Springer
    European journal of pediatrics 137 (1981), S. 177-184 
    Details
    ISSN: 1432-1076
    Keywords: EEG ; Evoked potentials ; Newborn ; Intracranial hemorrhage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The EEG, visual and auditory evoked potentials (VEP, AEP) were evaluated in 16 full-term newborn infants who had intracranial hemorrhage documented by computerized tomography (CT). Three of them had supratentorial, three, supra- and infratentorial hemorrhage, while the other ten had infra- or peri-tentorial bleeding. Three died during the neonatal period. Eight of the 13 surviving infants were neurologically normal and five were abnormal at the time of the follow-up. Those who had normal or mildly abnormal background EEGs all developed normally, while those whose neonatal EEG was severely abnormal subsequently developed neurological sequelae irrespective of the extent of intracranial hemorrhage. The EEG, VEP or AEP is of little value in the diagnosis of intracranial bleeding but the EEG is valuable in assessing the degree of associated parenchymatous damage and is of great prognostic significance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00441313
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