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  • 1
    Electronic Resource
    Electronic Resource
    The importance of the histologic processing of pelvic lymph nodes in the treatment of cervical cancer (1993)
    238 Main Street, Cambridge, Massachusetts 02142, USA : Blackwell Scientific Publications
    International journal of gynecological cancer 3 (1993), S. 0 
    Details
    ISSN: 1525-1438
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Four hundred and twenty surgical specimens from patients undergoing radical abdominal hysterectomy and complete pelvic lymphadenectomy for stage Ib, IIa or IIb cervical cancer underwent meticulous histologic and morphometric study. Complete processing of the extirpated lymphatic fatty tissue led to reproducible findings including the number of removed nodes, the number and size of tumor deposits in the nodes, and the location of the latter in the pelvis. An average of 32 nodes was removed per patient regardless of clinical size, tumor size, or stage. Thirty one per cent of patients with stage Ib disease had positive nodes as did 45% of those with stage IIb disease. The number of node metastases increased proportionally with the size of the primary tumor. In stage Ib 30% of the node metastases were smaller than 2 mm in diameter as were 21% of those in stage IIb. The size of the metastases was directly proportional to the size of the primary tumor. In patients with small tumors 43% of the nodes were smaller than 2 mm, as compared with 15% of those in patients with large tumors. The 5-year survival rate of patients with negative nodes was 89.3%. Survival dropped to 69.8% and 37.9% in patients with 1 or ≥ 4 positive nodes, respectively. The 5-year survival rate of patients with node metastases smaller than 2 mm and larger than 20 mm was 70% and 39%, respectively. In patients with identical numbers of positive nodes, survival decreased with increasing tumor size. In patients with tumors of a given size, the number of node metastases was an additional prognostic factor. The number of lymph nodes removed in a given patient is an objective measure of the thoroughness of a lymphadenectomy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1525-1438.1993.03010012.x
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  • 2
    Electronic Resource
    Electronic Resource
    John Wesley's Views on Science and Christianity: An Examination of the Charge of Antiscience (1994)
    New York : Cambridge University Press
    Church history 63 (1994), S. 378-392 
    Details
    ISSN: 0009-6407
    Source: Cambridge Journals Digital Archives
    Topics: History , Theology and Religious Studies
    Notes: Traditional nineteenth-century views of the relationship between science and Christianity have seen the two in a mortal conflict from which science emerged victorious over an obscurantist theology which sought to dominate the thinking of the new scientific class. Andrew Dickson White's A History of the Warfare of Science with Theology in Christendom (1896) represented a high point in such battlefield historiography. Recent writers have found the relationship to be more complex and less militaristic as a result of examining more closely the context in which the alleged battles took place. This paper will examine the case of English evangelist John Wesley (1703–1791), long a scapegoat of the warfare model. Wesley was often tarred with antiintellectualism during his lifetime and, in the ensuing two centuries, this argument has focused on his attitudes toward natural science. The effect has been to cast a leading religious figure of eighteenth-century England in the antiscience mold.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.2307/3167535
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  • 3
    Electronic Resource
    Electronic Resource
    Polarographic Characteristics of Carbohydrates. The Aldose Oximes and Semicarbazones (1962)
    s.l. : American Chemical Society
    Analytical chemistry 34 (1962), S. 145-147 
    Details
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ac60181a044
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  • 4
    Electronic Resource
    Electronic Resource
    Orbitally forced cyclical changes in the quantity of calcareous and siliceous microfossils in an Upper Jurassic to Lower Cretaceous pelagic basin succession, Bakony Mountains, Hungary (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Sedimentology 41 (1994), S. 0 
    Details
    ISSN: 1365-3091
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Rhythmic changes were observed in the quantity of radiolarians and calpionellids preserved in an Upper Jurassic to Lower Cretaceous deep water succession in the Bakony Mountains of Hungary. Statistical analysis revealed that for short periods (order of 100 kyr) the correlation of the two planktonic groups is negative. Over longer time intervals definite trends are recognized, which can be explained by the combined effect of facies transition, evolution of the calpionellids and rhythmic environmental (climatic) changes. Spectral analysis and time span calculations indicate that orbital forcing in the Milankovitch frequency band influenced the observed changes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3091.1994.tb01415.x
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  • 5
    Electronic Resource
    Electronic Resource
    Sodium Naphthalenide–Alkyl Halide Chemiluminescence (1967)
    [s.l.] : Nature Publishing Group
    Nature 214 (1967), S. 1006-1006 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The reaction is initiated by rapidly injecting an approximately 1 molar solution of sodium naphthalenide in dimethoxyethane into an excess of halide in dimethoxy-ethane which is protected from oxygen and moisture by a serum cap. Mixing is facilitated by stirring with nitrogen. Light emission is ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2141006a0
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  • 6
    Electronic Resource
    Electronic Resource
    A model for the role of HLA-DQ molecules in the pathogenesis of juvenile chronic arthritis (1991)
    Springer
    Rheumatology international 11 (1991), S. 191-197 
    Details
    ISSN: 1437-160X
    Keywords: Juvenile chronic arthritis ; MHC-class II association ; HLA-DQ molecules ; Restriction fragment length polymorphism ; Arthritogenic peptide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Restriction fragment length polymorphism (RFLP) typing of MHC-class II loci DRB, DQA1, DQB1, DQA2 and DPB1 was performed in 94 patients with seronegative juvenile chronic arthritis (JCA) and 184 random controls. Analysis of allele frequencies and MHC-class II 4-loci haplotypes indicate: (1) Susceptibility to JCA is more strongly associated with the HLA-DQ subregion than with the HLA-DR subregion, especially in early onset pauciarticular JCA (EOPA-JCA). (2) Haplotype and sequence analysis show two independent MHC-class II associations for susceptibility to EOPA-JCA, one located in DQA1, the other in DPB1. (3) Two RFLP defined patterns of the DQA1 locus, DQA1.5 (DQA1*0501) and DQA1.8 (DQA1*0401, *0601) are strongly associated with the disease. (4) Analysis of amino-acid (AA) sequences coded in exon 2 of DQA1 reveals an AA sequence of six AAs common to all three associated DQA1 alleles. This suggests a model that includes a functional role for HLA-DQ molecules in the pathogenesis of JCA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00332561
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  • 7
    Electronic Resource
    Electronic Resource
    Optisches Pumpen mit Mischlicht bei einer stoßinduzierten teilweisen Vermischung angeregterP-Zustände (1968)
    Springer
    The European physical journal 212 (1968), S. 315-329 
    Details
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The dependence of ground state spin polarization 〈S z〉 on the degree of collisionally induced excited state mixing has been calculated and discussed using the following mixtures of pumping light:σ + D 1 andσ − D 1 σ + D 2 andσ − D 2 as well asσ + D 2 andσ + D 1. The calculations in this first part have been performed on nuclear spin zero “one-electron” atoms using different mixing modells. Possibilities to determineP 1/2- andP 3/2-excited state mixing cross sections from easily detectable values par example the pass-through-zero of 〈S z〉 and to get informations on the validity of mixing modells are described. Category: atomic physics, optical pumping.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01380108
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  • 8
    Electronic Resource
    Electronic Resource
    Zur Polymerisation der Germaniumsäure, 1. Mitt. Bestimmung der mittleren Ladungszahlen und mittleren Polymerisationsgrade auf Grund potentiometrischer Titrationen (1964)
    Springer
    Monatshefte für Chemie 95 (1964), S. 1141-1165 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Zusammenfassung Das Polymerisationsverhalten von Germaniumsäure in wäßr. Lösung wird mit Hilfe potentiometrischer Titrationen untersucht. Hierzu werden Germaniumsäure-Lösungen verschiedener Konzentration (0,00159 bis 0,02388m) bei 25° C und konstanter Ionenstärke (0,5m resp. 1,0m-NaClO4) titriert, wobei innerhalb einer Titration die Ge-Konzentration konstant gehalten wird. Ein geeignetes Meß- und Auswerteverfahren erlaubt, aus den Potentialwerten Wasserstoffionen-Konzentrationen zu berechnen. Auf Grund der Meßdaten werden die Anzahl der je Ge-Atom gebundenen OH-Gruppen sowie mittlere Polymerisationsgrade bestimmt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00904708
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  • 9
    Electronic Resource
    Electronic Resource
    Zur Polymerisation der Germaniumsäure, 2. Mitt. Ermittlung der Komplexzusammensetzungen und Berechnung der zugehörigen Stabilitätskonstanten auf Grund graphischer Ausgleichsverfahren (1964)
    Springer
    Monatshefte für Chemie 95 (1964), S. 1166-1172 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Auf Grund der in der 1. Mitt. erhaltenen Meßdaten werden mit Hilfe graphischer Ausgleichsverfahren Näherungswerte für die Stabilitätskonstanten ermittelt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00904709
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  • 10
    Electronic Resource
    Electronic Resource
    Class I associations and frequencies of class II HLA-DRB alleles by RFLP analysis in children with rheumatoid-factor-negative juvenile chronic arthritis (1993)
    Springer
    Rheumatology international 13 (1993), S. 83-88 
    Details
    ISSN: 1437-160X
    Keywords: Juvenile chronic arthritis ; Early onset ; Juvenile rheumatoid arthritis ; HLA-DRB alleles
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A total of 94 patients with juvenile chronic arthritis (JCA) was tested for HLA class I by serology and for class II by RFLP typing. Early onset JCA (EOPA) is associated with HLA-A2, DR5 and DR8 in both males and females. The combination (joint occurrence) of these JCA associated alleles (A2, DR5, DR8) is frequently seen in patients with chronic iridocyclitis. Late onset pauciarticular disease has an increased frequency of HLA-B27, especially in males. Our data confirm that polyarticular JCA with early childhood onset (≤4 years) is associated with DR5 and DR8 and has a different immunogenetic background from polyarticular JCA with later childhood (〉4 years) onset (associated with DR4).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307739
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