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  • 1
    Electronic Resource
    Electronic Resource
    Plasma evolution from laser-driven gold disks. I. Experiments and results (1990)
    New York, NY : American Institute of Physics (AIP)
    Physics of Fluids 2 (1990), S. 2437-2447 
    Details
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Gold disk targets were irradiated with green (λ=0.53 μm) laser light at intensities between 0.5 and 5×1014 W/cm2 using shaped laser pulses. Plasma conditions near and below critical density (nc(approximately-equal-to)4×1021/cm3) were determined from three diagnostics. Streaked one-dimensional images of the M-band emission (2–3.5 keV) along the laser axis yield the peak emission trajectory. Temporally and spatially averaged measurements of the hard x-ray spectrum (4–25 keV) were used to determine the average coronal electron temperature. Holographic interferometry was used to determine the electron density profiles and scale lengths along the laser axis. The peak emission trajectory, electron temperature, and scale lengths are all in good agreement with simulations, but the magnitudes of the electron density profiles are not, as discussed in an accompanying paper [Phys. Fluids B 2, 2448 (1990)].
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.859509
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  • 2
    Electronic Resource
    Electronic Resource
    Interferenzmikroskopische Untersuchungen an Medulloblastom- und Glioblastomzellen (1968)
    Springer
    Cellular and molecular life sciences 24 (1968), S. 1232-1233 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The dry mass per unit area (g/µ2) for nucleus and cytoplasma was determinated by interference microscope from 1043 glioblastoma cells of 5 various glioblastomas and from 439 medulloblastoma cells of 4 various medulloblastomas. The values obtained from the glioblastoma cells are significantly higher than the values of medulloblastoma cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02146640
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  • 3
    Electronic Resource
    Electronic Resource
    Thrombocytopenia induced by erucic acid therapy in patients with X-linked adrenoleukodystrophy (1993)
    Springer
    Journal of molecular medicine 71 (1993), S. 802-805 
    Details
    ISSN: 1432-1440
    Keywords: Adrenoleukodystrophy ; Adrenomyeloneuropathy ; Thrombocytopenia ; Erucic acid ; Therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Five patients with various clinical and genetic phenotypes of adrenoleukodystrophy were treated with a diet enriched with glycerol trioleate and glycerol trierucate (GTE). In all patients platelet counts decreased upon the administration of GTE, but no bleeding symptoms occurred in any of the patients, and bleeding time remained normal. Pseudothrombocytopenia was excluded in all patients. Thrombocytopenia was marked (84000–37000/mm) in three of the patients but was fully reversible after discontinuation of GTE. Mean platelet volumes were abnormally increased in all patients. When GTE was again administered by stepwise increasing the daily dose, platelet counts showed a clearly dose-dependent decrease. Bone marrow biopsies revealed no evidence of reduced megakaryocytopoiesis. The data indicate that in patients with adrenoleukodystrophy treated with GTE platelet counts should be closely monitored because thrombocytopenia may limit the maximal daily intake of GTE.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00190322
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  • 4
    Electronic Resource
    Electronic Resource
    Proteinuria after renal transplantation: Diagnosis with highly sensitive silver stain in sodium dodecylsulphate-polyacrylamide gradient gel electrophoresis (1991)
    Springer
    Journal of molecular medicine 69 (1991), S. 847-852 
    Details
    ISSN: 1432-1440
    Keywords: Renal transplantation ; Electrophoresis ; Silver stain ; Coomassie stain ; Rejection ; Proteinuria ; Cyclosporine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sodium dodecylsulphate-polyacrylamide gel electrophoresis (SDS-PAGE) of urinary proteins is becoming increasingly significant in monitoring renal allograft recipients. After conventional Coomassie Blue staining, changes in renal proteinuric patterns during acute renal transplant rejection could not be seen in many cases. Discrimination between rejection and nephrotoxic side effects of cyclosporine overdosage was also not possible. We therefore examined the possible advantages of a highly sensitive silver staining technique in this study. A total of 734 urine samples obtained from 38 patients after allogenic kidney transplantation were examined by SDS-PAGE with consecutive Coomassie Blue and silver staining. Twenty-two histologically proven rejections and 20 cyclosporine overdosage episodes were diagnosed in these patients within a time period of up to 524 days after transplantation. No changes in proteinuric patterns were seen in 9 of 22 patients after Coomassie stain during rejection, and only 12 cases showed a rise of glomerular protein bands, whereas silver stain revealed an increase in 19 of 22 cases. Discrimination between cyclosporine overdosage and rejection was possible with a probability ofp〈0.001 after silver stain when using the changes in the number of glomerular protein bands as a criterion. These findings suggest that application of a highly sensitive silver stain instead of the conventional Coomassie stain after SDS-PAGE reflects considerable progress in monitoring renal allograft recipients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01649458
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  • 5
    Electronic Resource
    Electronic Resource
    Cauda equina syndrome with multiple lumbar diverticula complicating long-standing ankylosing spondylitis (1994)
    Springer
    Journal of molecular medicine 72 (1994), S. 1056-1059 
    Details
    ISSN: 1432-1440
    Keywords: Ankylosing spondylitis ; Bechterew's disease ; Cauda equina syndrome ; Lumbar diverticula
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A patient with cauda equina syndrome complicating long-standing inactive ankylosing spondylitis is described. The first neurological symptoms started 15 years after the onset of ankylosing spondylitis. Over a follow-up period of 12 years the cauda equina syndrome showed a slowly progressive but disabling course leading to sensory disturbances in the lumbar and sacral dermatomes, weakness and wasting of the muscles innervated by these nerve roots, sphincter disturbances, and impotence. Magnetic resonance imaging, computed tomography, and lumbar myelography showed enlargement of the dural sac with multiple lubar diverticula eroding the lumbosacral vertebrae. The pathophysiology of the cauda equina syndrome in ankylosing spondylits is unclear. Surgical treatment seems justified only in patients with a short history of neurological symptoms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00577755
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  • 6
    Electronic Resource
    Electronic Resource
    Ventricular fibrillation related to coronary spasm in patients without significant coronary or other structural heart disease (1994)
    Springer
    Journal of molecular medicine 72 (1994), S. 307-312 
    Details
    ISSN: 1432-1440
    Keywords: Ventricular fibrillation ; Coronary spasm ; Silent ischemia ; Implantable defibrillator
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We present three patients without significant coronary or other structural heart disease who were resuscitated after ventricular fibrillation attributed to coronary spasm. Angina pectoris was present in two of the cases and silent myocardial ischemia in the third. All patients were given calcium antagonists at discharge. A defibrillator was also implanted in the patient with silent myocardial ischemia because further episodes of ischemia would probably have occurred without premonitory symptoms. Coronary spasm might be a mechanism of ventricular fibrillation in patients without significant structural heart disease. Diagnostic tests should therefore be performed to confirm or exclude coronary spasm in such cases. The implantation of an automatic defibrillator seems justified in selected patients with documented coronary spasm, silent myocardial ischemia, and associated sustained ventricular tachyarrhythmia, although prospective studies are not yet available.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00180046
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  • 7
    Electronic Resource
    Electronic Resource
    Unterschiedlicher Mitoseablauf bei neuroektodermalen und mesodermalen Tumoren (1967)
    Springer
    Naturwissenschaften 54 (1967), S. 620-620 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00591434
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  • 8
    Electronic Resource
    Electronic Resource
    Interferenzmikroskopische Untersuchungen an Medulloblastomen und Sarkomen (1968)
    Springer
    Naturwissenschaften 55 (1968), S. 448-449 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00602675
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  • 9
    Electronic Resource
    Electronic Resource
    Myotonic dystrophy and limb girdle muscular dystrophy in one family (1994)
    Springer
    Journal of molecular medicine 72 (1994), S. 409-413 
    Details
    ISSN: 1432-1440
    Keywords: Myotonic dystrophy ; Limb girdle muscular dystrophy ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A family is reported in which a 29-year-old woman showed the clinical features of myotonic dystrophy while her 26-year-old brother presented with the clinical picture of limb girdle syndrome. In the affected female, direct genetic testing for the specific myotonic dystrophy mutation on chromosome 19 revealed abnormal expansion of a repeat unit containing the three nucleotides cytosine, thymine, and guanine (CTG) — typical for myotonic dystrophy — while her diseased brother displayed two normal alleles. This supports the hypothesis of the extremely rare occurrence of two clinically and genetically different myopathies in one family. Genetic analysis of six other family members showed that the father of the diseased siblings as well as all of his three brothers and sisters had a pathological CTG repeat expansion, and that the other two family members tested had a normal allelic pattern. The number of CTG repeats in the diseased women was approximately tenfold higher than in her asymptomatic relatives who revealed an abnormal allelic pattern. The increase in CTG repeats with transmission to a subsequent generation in this family was paralleled by a dramatic increase in the severity of myotonic dystrophy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00252840
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  • 10
    Electronic Resource
    Electronic Resource
    Dysplastic gangliocytoma of cerebellum in a newborn (1992)
    Springer
    Pediatric radiology 22 (1992), S. 131-133 
    Details
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A cerebellar lesion was detected by ultrasonography (US) in a symptomatic newborn. Magnetic Resonance Imaging (MRI) demonstrated this lesion as a gyriform structure. Therefore a rare dysplastic gangliocytoma was suspected, which was compatible with histopathology. Immunohistochemical studies (monoclonal antibody Ki-67) showed signs of progression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02011314
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