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  • 1990-1994  (5)
  • 1960-1964  (1)
  • Life and Medical Sciences  (3)
  • gemmules  (3)
  • 1
    ISSN: 1573-5117
    Keywords: gemmules ; desiccation ; low temperature ; Porifera and Anheteromeyenia ryderi
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Gemmules of Anheteromeyenia ryderi survived 24 h exposure to air temperatures as low as −20 °C under laboratory conditions. Drying the gemmules of A. ryderi at 5 °C under laboratory conditions resulted in a reduced viability and a slower germination rate following rehydration compared with undried control gemmules. Only 25% of the gemmules germinated after drying for one month. Up to 25% of the gemmules of A. ryderi that were tested survived aerial exposure from early November to early April when a pond in Connecticut inhabited by this sponge was drained. During this period air temperatures dropped to as low as −16 °C. Continued aerial exposure of the gemmules during the summer resulted in nearly complete gemmule mortality.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 218 (1991), S. 107-112 
    ISSN: 1573-5117
    Keywords: gemmules ; cold tolerance ; sponge ; Spongilla lacustris
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Most green gemmules of Spongilla lacustris survived enclosure in ice at −20 °C for up to 30 days; however, their rate of germination at 20 °C was less rapid than that of control gemmules. The length of time spent at low temperature had little effect on gemmule survival. In contrast, repeated cooling to −20 °C and warming to 4 °C led to a progressive decline in gemmule viability. These results indicate that cold injury occurs primarily during transitions between high and low temperatures.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 242 (1992), S. 33-39 
    ISSN: 1573-5117
    Keywords: gemmules ; salinity tolerance ; dormancy ; Porifera and Eunapius fragilis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Gemmules of the freshwater sponge, Eunapius fragilis (Leidy), survived exposure to 30 ppt natural sea water at 20 °C for up to 27 days and to 37 ppt Instant Ocean sea water for up to at least 9 days. This high salinity tolerance may have made possible the dispersal of the sponge on the hulls of ocean-going ships that frequented freshwater ports. The gemmules also survived 9-day exposures to 5% NaCl, 20% NaCl and some artificial sea waters containing only a few of the major ions. All of these solutions inhibited germination of the gemmules during the period of exposure, and treatment with 30 ppt natural sea water, 37 ppt Instant Ocean sea water, 20% NaCl and a solution containing Na+, Cl− and SO inf4 sup2− had a persisting inhibitory effect on gemmule germination after the gemmules were returned to pond water at 20 °C. Many of the gemmules that did not germinate under favorable conditions following treatment could be stimulated to germinate after they were chilled at 4 °C for 4 or more months. Such gemmule inhibition mimics natural diapause which also is broken by exposure to low temperature.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 142 (1962), S. 531-535 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 50 (1992), S. 120-127 
    ISSN: 0730-2312
    Keywords: intravesical therapy ; superficial bladder cancer ; transitional cell carcinoma ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Approximately 70% of all bladder cancers are superficial at the time of presentation. Superfecial bladder cancer includes tumors confined to the urothelium (clinical stage Ta) or lamina propria (stage T1) and flat carcinoma is situ (stage Tis). Because the biological behavior of bladder neoplasms is variable, several important prognostic factros must be addressed. Multivariate analyses have shown that factors predictive of tumor recurrence and tumor progression include multifocal tumors, high grade tumors. T1 tumors and positive urinary cytology after transurethral resection (TUR). The patient with superficial bladder cancer should be monitored via endoscopy supplemented by urinary cytology, using either voided or bladder irrigation specimens and urinalysis. Frequent intravenous urography is not required, even in high grade tumors, as long as the clinical and pathologic studies remain negative and the patient is asymptomatic.The “gold standard” of treatment for superficial is TUR of the entire tumor. Despite TUR, new tumors will occur in approximately 50% of all patients; those at highest risk for tumor recurrence and progression require adjuvant intravesical therapy after TUR. A variety of drugs are used as intravesical therapy, including thiotepa, mitomycin C, doxorubicin hydrochloride, Bacillus Calmette-Guerin (BCG), epirubicin, and interferon. Although associated with the most toxicity, BCG appears to be the most effecacious agent in increasing the time to recurrence and progression and in reducing the recurrence rate. © 1992 Wiley-Liss, Inc.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 144 (1990), S. 77-83 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The expression of the early genes JE and KC has been examined in Balb/c 3T3 cells treated with bacterial lipopolysaccharide (LPS). Previous studies showed that JE and KC mRNAs are induced in murine peritoneal macrophages treated with LPS, suggesting a role for these genes in inflammatory responses. Consistent with this possibility are recently published cDNA sequences which document that both genes are members of a superfamily of inflammation- and/or growth-related cytokines. In the present study, we provide evidence that the mRNAs for JE and KC are specifically induced by LPS treatment of Balb/c 3T3 cells. The LPS-stimulated expression of JE and KC was dose dependent, and exhibited a transient time course; message levels were maximal between 2 and 4 hr and declined by 8 hr. The LPS-augmented accumulation of JE and KC occurred even in the presence of cyclohexamide, which additionally had a superinducing effect on the expression of both genes. Cyclohexamide alone, in the absence of LPS, also induced JE and KC mRNA accumulation. LPS-stimulated JE and KC mRNA expression was dependent upon the stimulation of transcription as determined by nuclear “run-on” studies. Comparative analyses indicated that, under the conditions employed, LPS was a somewhat less effective stimulant of JE expression than PDGF or EGF, and was more effective than PDGF and equivalent to EGF in its ability to augment KC accumulation. Unlike PDGF and EGF, LPS did not stimulate DNA synthesis by Balb/c 3T3 cells at any time over the 72 hr period examined. The ability of the inflammatory, non-mitogenic stimulus LPS to selectively induce JE and KC mRNA expression by fibroblasts may reflect their participation in inflammation and wound healing as secretory cells.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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