ISSN:
1432-1920
Keywords:
Brain tumours
;
Ultrasonography
;
Computed tomography
;
Stereotactic biopsy
;
Transcranial colour-coded real time sonography
;
Glloma
;
Central nervous system
;
Duplex sonography
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Transcranial colour-coded real-time sonography (TCCS) was carried out in 25 patients with brain tumours to determine whether this noninvasive method provides additional information about the extent of solid tumour, its differentiation from oedema, and its tissue components. All 25 patients had serial computed tomography (CT)-guided stereotactic biopsies. Comparison of ultrasound, CT and histological findings revealed that the vast majority of contrast enhancing areas on CT were hyperechogenic (32/33; 97%) and contained tumour tissue (29/32; 91%). Hyperechogenic areas always represented solid tumour (23/23 patients), even when CT showed low density non-enhancing lesions. In lestons hypoechogenic on TCCS and low density on CT, histology consistently revealed necrotic tumour (7/7). Biopsies obtained from parenchyma with normal echogenicity revealed tumour in only 3 of 16 speciemens. Despite the high specificity of TCCS in the differentiation of tumour components, its sensitivity to tumour was inferior to that of CT (24/25; 96%). TCCS thus allows noninvasive preoperative identification of tumour tissue and its extent setting.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00600414
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