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  • 1990-1994  (3)
  • 1925-1929
  • 25.70.Lm  (1)
  • 25.85.Ge  (1)
  • Biological behaviour  (1)
  • Flow cytometry  (1)
Material
Years
  • 1990-1994  (3)
  • 1925-1929
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 117 (1991), S. 568-574 
    ISSN: 1432-1335
    Keywords: Heterotransplantation ; Nude mice ; Osteosarcoma ; Squamous carcinoma ; Histological changes ; Biological behaviour
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fifteen xenograft tumour lines (4 osteosarcomas and 11 squamous carcinomas) were established on nude mice in numerous passages. Over a period of 4 years, samples were taken and studied systematically in more than 4000 histological slides. Of the tumour lines, 12 (4 osteosarcomas and 8 squamous carcinomas) showed remarkable dedifferentiation, but also redifferentiation towards a higher grade. There was a correlation between the rate of tumour takes in mice and poor prognosis in patients, but none between tumour doubling time and the phases of the cell cycle. Altogether, the results showed a great heterogeneity of human xenotransplants in terms of biological behaviour and morphological changes.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 116 (1990), S. 315-317 
    ISSN: 1432-1335
    Keywords: Multiclonal tumor ; Irradiation ; Flow cytometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary It was shown in the present study that irradiation of a multiclonal tumor may destroy near-diploid cell clones preferentially, while the stemline with high DNA content continues to grow after temporary arrest. This experimental observation confirms recent clinical studies.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1434-601X
    Keywords: 25.70.Lm ; 25.85.Ge
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Strongly damped collisions were studied in uranium induced reactions on110Pd and124Sn target nuclei near the barrier. The excitation-energy splitting was deduced from binary reaction yields and those in which the heavy fragment undergoes sequential fission. For systems with 87≦Z≦95 for the heavy fragment, the excitation energy is concentrated in the lighter nucleus, at best shared equally. The results indicate a non-equilibrated energy dissipation, and support nucleon exchange based on average single-particle strength functions as the underlying dissipation mechanism at the barrier.
    Type of Medium: Electronic Resource
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