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  • 1990-1994  (4)
  • Aspergillus versicolor  (2)
  • Flow cytometry  (1)
  • Nasal resistance  (1)
  • Transitional cell cancer  (1)
  • (Bacillus)
Source
Material
Years
  • 1990-1994  (4)
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Granulomatous lesions in the lung induced by inhalation of mold spores (1994)
    Springer
    Virchows Archiv 424 (1994), S. 661-668 
    Details
    ISSN: 1432-2307
    Keywords: Lung granuloma ; Bronchus-associated lymphoid tissue ; Mold inhalation ; Aspergillus versicolor ; Germ-free rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The health hazards associated with grain dust exposure have been recognized as a cause of lung diseases. In the present study, we used germ-free rats exposed to Aspergillus versicolor to elucidate the mechanism for the lung damage induced by grain dust exposure. One month after exposure to the mold, remarkable proliferation of bronchus-associated lymphoid tissues with germinal centres was induced by aspiration of mold spores. After 1 month, alveolar macrophages increased, becoming foamy macrophages by ingestion and digestion of mold spores. They expressed interleukin (IL)-1, Ia antigens and intercellular adhesion molecule-1 intensely and occasionally bound lymphocytes. Numerous lymphocytes infiltrated the granulomatous lesions which consisted of accumulated foamy macrophages and some T lymphocytes which carried IL-2 receptor. Granulomatous lesions were identified in the entire lung, especially around bronchioles. They extended from alveolar ducts to alveolar spaces for 6 months after exposure to the mold. The macrophage appears to be a key effector cell in granulomatous reactions to inhaled molds.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00195782
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Granulomatous lesions in the lung induced by inhalation of mold spores (1994)
    Springer
    Virchows Archiv 424 (1994), S. 661-668 
    Details
    ISSN: 1432-2307
    Keywords: Lung granuloma ; Bronchus-associated lymphoid tissue ; Mold inhalation ; Aspergillus versicolor ; Germ-free rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The health hazards associated with grain dust exposure have been recognized as a cause of lung diseases. In the present study, we used germ-free rats exposed toAspergillus versicolor to elucidate the mechanism for the lung damage induced by grain dust exposure. One month after exposure to the mold, remarkable proliferation of bronchus-associated lymphoid tissues with germinal centres was induced by aspiration of mold spores. After 1 month, alveolar macrophages increased, becoming foamy macrophages by ingestion and digestion of mold spores. They expressed interleukin (IL)-1, Ia antigens and intercellular adhesion molecule-1 intensely and occasionally bound lymphocytes. Numerous lymphocytes infiltrated the granulomatous lesions which consisted of accumulated foamy macrophages and some T lymphocytes which carried IL-2 receptor. Granulomatous lesions were identified in the entire lung, especially around bronchioles. They extended from alveolar ducts to alveolar spaces for 6 months after exposure to the mold. The macrophage appears to be a key effector cell in granulomatous reactions to inhaled molds.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01069748
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Flow cytometric evaluation of Thomsen-Friedenreich antigen on transitional cell cancer using monoclonal antibody (1990)
    Springer
    Urological research 18 (1990), S. 107-111 
    Details
    ISSN: 1434-0879
    Keywords: Transitional cell cancer ; Flow cytometry ; T antigen ; Monoclonal antibody
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 31 transitional cell cancer (TCC) tissues and 5 normal bladder muscosae (NBM), we compared the results of flow cytometry (FCM) and immunohistochemical examination in evaluating the expression of Thomsen-Friedenreich antigen (T-Ag) using a monoclonal antibody. On immunohistochemical examination, 14 (45%) cancer tissues showed T-Ag, while 7 (23%) cancer tissues and all NBM showed only cryptic T-Ag, which was detected only after neurminidase treatment. Ten (32%) high grade cancer tissues showed neither T-Ag nor cryptic T-Ag. On FCM the T-Ag positive cells (TPC) and the T-Ag positive cells after neuraminidase treatment (nTPC) were counted in fresh cell suspensions. FCM was more sensitive than immunohistochemical study in detecting T-Ag. Additionally, FCM revealed that some tumors had both T-Ag and cryptic T-Ag at the same time. The ratio of nTPC to TPC was well correlated with the stage or grade of the tumor and may be a more reliable marker of TCC than the expression of T-Ag assessed by immunohistochemical techniques.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00302469
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    A comparison of current expressions of nasal patency (1993)
    Springer
    European archives of oto-rhino-laryngology and head & neck 250 (1993), S. 249-252 
    Details
    ISSN: 1434-4726
    Keywords: Nasal resistance ; Rhinomanometry ; Nasal patency
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Rhinomanometry is well established as a useful clinical method for objective assessment of nasal patency, although several expressions of nasal patency have been reported and universal standardization has not been achieved. In this communication, nasal resistances were calculated from the equation R = ΔP/V (R; resistance; ΔP; transnasal differential pressure; V; nasal airflow) at ΔP 100 Pa and at peak flow. Time-averaged nasal resistances and integrated nasal patencies were measured in 350 adult patients by Rhinorheograph MPR-1100 and processed by a NI-101 computer program. The values from the equation R = ΔP/V at ΔP 100 Pa were slightly lower than those from the same equation at peak flow or those from the time-averaging method. Correlations between the values of nasal resistance at peak flow and the time averaging method were very close to the line of identity. No significant correlations were demonstrated between integrated nasal patency and the values from the other three expressions. The differences of the results from these expression are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00171535
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    Paper (German National Licenses)
    Fulltext
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