ISSN:
1435-1463
Keywords:
3,4-Dihydroxyphenylserine
;
blood pressure
;
orthostatic hypotension
;
autonomic failure
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Treatment with L-threo-3,4-dihydroxyphenylserine (L-threo-dops), a synthetic precursor of norepinephrine, significantly increased upright blood pressure in patients with multiple system atrophy but had no effect on the upright blood pressure of patients with pure autonomic failure. These results suggest that the site of action of L-threo-dops is central and that its pressor effect requires intact peripheral sympathetic neurons.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02260889
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