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  • 1990-1994  (2)
  • 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide  (1)
  • Adult  (1)
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Years
  • 1990-1994  (2)
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Comparative study of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and tritiated thymidine in a chemosensitivity test using collagen gel matrix (1993)
    Springer
    Urological research 21 (1993), S. 83-88 
    Details
    ISSN: 1434-0879
    Keywords: Chemosensitivity test ; Collagen gel matrix ; 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide ; Human transitional cell carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An organ culture system using collagen gel matrix (CGM) was modified and established successfully as a rapid and convenient method for determination of anti-cancer drug sensitivities. The cell viability of a tumor fragment was measured by the reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) to a colored formazan product, which allowed for quantitative and simple analysis. The sensitivities of KK-47 bladder tumor from nude mice to various anti-cancer drugs tested corresponded closely to those determined in the originial CGM assay system using tritiated thymidine, which has a high clinical correlation. Our modified method can be used as a practical and highly reproducible chemosensitivity test in vitro.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01788824
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Immunohistopathology of variations of human olfactory mucosa (1991)
    Springer
    European archives of oto-rhino-laryngology and head & neck 248 (1991), S. 370-375 
    Details
    ISSN: 1434-4726
    Keywords: Human olfactory mucosa ; Fetus ; Adult ; Degeneration ; Immunohistopathology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The characteristics of the human olfactory mucosa were studied immunohistologically. Regular, tonal distribution of the supporting cells, multilayered olfactory receptor cells and basal cells was commonly found in the olfactory mucosa of the human fetus. In contrast, most of the olfactory mucosa in the adult varied to some extent. In the relatively thick, slightly degenerated olfactory mucosa, olfactory marker protein positive receptor cells were arranged irregularly. The most common evidence for variation was the decrease or disappearance of the olfactory receptor cells. Serous-type lactorferrin-containing glandular acini were characteristically found beneath degenerated epithelium. Islands of respiratory epithelium were also seen. The ductules of the Bowman's glands were distended and the openings of these ductules were wide. There was invagination or epithelial cell processes into the glandular lumina. These findings suggest that the epithelial cells of Bowman's glands play an important role in the regeneration of the human olfactory mucosa.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00169031
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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