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  • 1990-1994  (2)
  • 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide  (1)
  • Aligator plate  (1)
Material
Years
  • 1990-1994  (2)
Year
Keywords
  • 1
    ISSN: 1434-0879
    Keywords: Chemosensitivity test ; Collagen gel matrix ; 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide ; Human transitional cell carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An organ culture system using collagen gel matrix (CGM) was modified and established successfully as a rapid and convenient method for determination of anti-cancer drug sensitivities. The cell viability of a tumor fragment was measured by the reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) to a colored formazan product, which allowed for quantitative and simple analysis. The sensitivities of KK-47 bladder tumor from nude mice to various anti-cancer drugs tested corresponded closely to those determined in the originial CGM assay system using tritiated thymidine, which has a high clinical correlation. Our modified method can be used as a practical and highly reproducible chemosensitivity test in vitro.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0932
    Keywords: Rachis cervical ; Arthrodèse postérieure ; Instrumentation ; Arthrodèse par plaques ; Plaques “Alligator” ; Instabilité cervicale ; Cervical spine ; Posterior fusion ; Instrumentation ; Posterior fixation ; Plate fixation ; Aligator plate ; Cervical instability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary We have designed a new type of clamping plate called the “Alligator plate” for posterior cervical spinal fixation and used it in some cases with cervical instability. Seventeen patients with cervical instability treated by posterior cervical fixation using Alligator plate were clinically evaluated. As a control group, 21 patients treated by a wire fixation method (cerclage) were also evaluated. Clinical results were evaluated radiographically on dynamic flexion-extension lateral radiographs with confirmation of the fusion mass on oblique-view radiographs. The results of Alligator plate fixation were excellent in 15 patients, good in one and poor in one. The results of wire fixation were excellent in 15 patients, good in three, fair in one and poor in two. A safe and simple alternative instrumentation, the Alligator plate has sufficient stability to be useful for treating instability of the lower cervical spine.
    Notes: Résumé Nous avons créé un nouveau type de plaque à machoire appelée plaque “Alligator” destinée à l'arthrodèse postérieure du rachis cervical et nous l'avons appliquée à quelques cas d'unstabilité cervicale. L'évaluation clinique a porté sur 17 cas présentant une instabilité cervicale traitée par arthrodèse postérieure à l'aide de plaques “Alligator”. L'évaluation a aussi porté sur un groupe témoin comportant 21 cas traités par la méthode du cerclage. Les résultats cliniques ont été évalués radiologiquement d'après les clichés dynamiques de profil en flexion-extension, et confirmation de la fusion osseuse sur les radios de profil. Les résultats obtenus dans le groupe traité par les plaques “Alligator” ont été excellents chez 15 patients, bons chez l'un et mauvais chez un autre. Les résultats obtenus avec le cerclage ont été excellents chez 15 patients, bons chez trois, passables chez un et mauvais chez deux. La plaque “Alligator” représente une alternative intéressante en matière d'implants cervicaux; elle est d'une stabilité suffisante et peut se montrer de ce fait utile dans le traitement de l'instabilité du rachis cervical inférieur.
    Type of Medium: Electronic Resource
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