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  • 1
    ISSN: 1438-2199
    Keywords: Amino acids ; N-Acetylcysteine ; Cysteine ; Glutathione ; Diethyl maleate ; Perfused rat liver
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Effect ofN-acetyl-l-cysteine (NAC) administration on cysteine and glutathione (GSH) contents in rat liver and kidney was studied using intact and diethyl maleate (DEM)-treated rats and perfused rat liver. Cysteine contents increased rapidly, reaching peak at 10 min after intraperitoneal NAC administration. In liver mitochondria it increased slowly, reaching peak at 60 min. GSH content did not change significantly in these tissues. However, in liver and kidney depleted of GSH with DEM, NAC administration restored GSH contents in 60 and 120 min, respectively. Perfusion with 10 mM NAC resulted in 76% increase in liver cysteine content, but not in GSH content. Liver perfusion of DEM-injected rats with 10 mM NAC restored GSH content by 15%. Present findings indicate that NAC is an effective precursor of cysteine in the intact liver and kidney and in the perfused rat liver, and that NAC stimulated GSH synthesis in GSH-depleted tissues.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1572-9605
    Keywords: Critical current density ; Ag addition ; grain alignment ; flux pinning ; defect structure ; YBCO ; melt-texturing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
    Notes: Abstract Silver has been previously added to the melt-textured YBa2Cu3O7−x in order to increase the critical current density (J c ) of these materials. However, the effect of this addition on theJ c is presently unclear. The purpose of this study is to investigate the effect of silver on both critical current density and the microstructure of the melt-textured YBa2Cu3O7−x superconductors by means of X-ray diffraction, optical polarized microscopy, and transmission electron microscopy (TEM). TheJ c of the MTG YBCO/Ag samples is more than 104A/cm2 under the 5 kOe magnetic field. It has been shown that as the concentration of silver increases, the fraction of the 211 phase dispersed within the 123 matrix decreases. Therefore, theJ c slightly decreases. These results, together with the effect of the 211 phase, dislocations, and other structure defects on flux pinning, are described in this paper.
    Type of Medium: Electronic Resource
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