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Digitale Medien

Elevated levels of soluble CD8 antigen in sera of patients with psoriasis — a possible sign of suppressor/cytotoxic T-cell activation (1990)

Kapp, A.

Springer

Archives of dermatological research 282 (1990), S. 6-7

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Details

ISSN: 1432-069X

Schlagwort(e): Psoriasis ; T-cell activation ; CD8 antigen ; Psoriatic arthritis ; Atopic dermatitis

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary Increased levels of the soluble CD8 antigen probably represent a sign of suppressor T-cell activity. The concentration of CD8 was measured in the sera of patients with psoriasis without psoriatic arthritis (n=25) and atopic dermatitis (n=26), exhibiting moderate to severe disease activity, in comparison with nonatopic healthy controls (n=31) using an ELISA technique. CD8 levels were found to be significantly elevated in psoriatic patients as compared with healthy controls (p≤0.002). Increase in CD8 may be due to suppressor T-cell activation in the skin of patients with psoriasis.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00505637

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